Evaluating the Safety of Retroviral Vectors Based on Insertional Oncogene Activation and Blocked Differentiation in Cultured Thymocytes

por Zhou, Sheng, Fatima, Soghra, Ma, Zhijun, Wang, Yong-Dong, Lu, Taihe, Janke, Laura J, Du, Yang, Sorrentino, Brian P
Publicado 2016

Fenofibrate reduces osteonecrosis without affecting antileukemic efficacy in dexamethasone-treated mice

por Finch, Emily R., Payton, Monique A., Jenkins, David A., Cai, Xiangjun, Li, Lie, Karol, Seth E., Relling, Mary V., Janke, Laura J.
Publicado 2020

Asparaginase Potentiates Glucocorticoid-Induced Osteonecrosis in a Mouse Model

por Liu, Chengcheng, Janke, Laura J., Kawedia, Jitesh D., Ramsey, Laura B., Cai, Xiangjun, Mattano, Leonard A., Boyd, Kelli L., Funk, Amy J., Relling, Mary V.
Publicado 2016

A genetic mouse model with postnatal Nf1 and p53 loss recapitulates the histology and transcriptome of human malignant peripheral nerve sheath tumor

por Inoue, Akira, Janke, Laura J, Gudenas, Brian L, Jin, Hongjian, Fan, Yiping, Paré, Joshua, Clay, Michael R, Northcott, Paul A, Hirbe, Angela C, Cao, Xinwei
Publicado 2021

Asparaginase combined with discontinuous dexamethasone improves antileukemic efficacy without increasing osteonecrosis in preclinical models

por Karol, Seth E., Janke, Laura J., Panetta, John C., Ramsey, Laura B., Cai, Xiangjun, Payton, Monique A., Jenkins, David A., Evans, William E., Relling, Mary V.
Publicado 2019

Msh2 deficiency leads to dysmyelination of the corpus callosum, impaired locomotion, and altered sensory function in mice

por Diouf, Barthelemy, Devaraju, Prakash, Janke, Laura J., Fan, Yiping, Frase, Sharon, Eddins, Donnie, Peters, Jennifer L., Kim, Jieun, Pei, Deqing, Cheng, Cheng, Zakharenko, Stanislav S., Evans, William E.
Publicado 2016

G3BP2-KIT drives leukemia amenable to kinase inhibition in Ph-like ALL

por Iacobucci, Ilaria, Fukano, Reiji, D. Friske, Jake, Qu, Chunxu, Janke, Laura J., Zhao, Yaqi, Baviskar, Pradyuamna, A. Backhaus, Emily, Chockley, Peter, Seth, Aman, Laird, A. Douglas, Advani, Anjali S., Mullighan, Charles G.
Publicado 2022

3’ UTR-truncated HMGA2 overexpression induces non-malignant in vivo expansion of hematopoietic stem cells in non-human primates

por Bonner, Melissa A., Morales-Hernández, Antonio, Zhou, Sheng, Ma, Zhijun, Condori, Jose, Wang, Yong-Dong, Fatima, Soghra, Palmer, Lance E., Janke, Laura J., Fowler, Stephanie, Sorrentino, Brian P., McKinney-Freeman, Shannon
Publicado 2021

Antileukemic Efficacy of Continuous vs Discontinuous Dexamethasone in Murine Models of Acute Lymphoblastic Leukemia

por Ramsey, Laura B., Janke, Laura J., Payton, Monique A., Cai, Xiangjun, Paugh, Steven W., Karol, Seth E., Kamdem, Landry Kamdem, Cheng, Cheng, Williams, Richard T., Jeha, Sima, Pui, Ching-Hon, Evans, William E., Relling, Mary V.
Publicado 2015

Mutant Samd9l expression impairs hematopoiesis and induces bone marrow failure in mice

por Abdelhamed, Sherif, Thomas, Melvin E., Westover, Tamara, Umeda, Masayuki, Xiong, Emily, Rolle, Chandra, Walsh, Michael P., Wu, Huiyun, Schwartz, Jason R., Valentine, Virginia, Valentine, Marcus, Pounds, Stanley, Ma, Jing, Janke, Laura J., Klco, Jeffery M.
Publicado 2022

Integrative network analysis reveals USP7 haploinsufficiency inhibits E-protein activity in pediatric T-lineage acute lymphoblastic leukemia (T-ALL)

por Shaw, Timothy I., Dong, Li, Tian, Liqing, Qian, Chenxi, Liu, Yu, Ju, Bensheng, High, Anthony, Kavdia, Kanisha, Pagala, Vishwajeeth R., Shaner, Bridget, Pei, Deqing, Easton, John, Janke, Laura J., Porter, Shaina N., Ma, Xiaotu, Cheng, Cheng, Pruett-Miller, Shondra M., Choi, John, Yu, Jiyang, Peng, Junmin, Gu, Wei, Look, A. Thomas, Downing, James R., Zhang, Jinghui
Publicado 2021

Identification of small molecules that mitigate vincristine‐induced neurotoxicity while sensitizing leukemia cells to vincristine

por Diouf, Barthelemy, Wing, Claudia, Panetta, John C., Eddins, Donnie, Lin, Wenwei, Yang, Wenjian, Fan, Yiping, Pei, Deqing, Cheng, Cheng, Delaney, Shannon M., Zhang, Wei, Bonten, Erik J., Crews, Kristine R., Paugh, Steven W., Li, Lie, Freeman, Burgess B., Autry, Robert J., Beard, Jordan A., Ferguson, Daniel C., Janke, Laura J., Ness, Kirsten K., Chen, Taosheng, Zakharenko, Stanislav S., Jeha, Sima, Pui, Ching‐Hon, Relling, Mary V., Eileen Dolan, M., Evans, William E.
Publicado 2021

CCL22 mutations drive natural killer cell lymphoproliferative disease by deregulating microenvironmental crosstalk

por Baer, Constance, Kimura, Shunsuke, Rana, Mitra S., Kleist, Andrew B., Flerlage, Tim, Feith, David J., Chockley, Peter, Walter, Wencke, Meggendorfer, Manja, Olson, Thomas L., Cheon, HeeJin, Olson, Kristine C., Ratan, Aakrosh, Mueller, Martha-Lena, Foran, James M., Janke, Laura J., Qu, Chunxu, Porter, Shaina N., Pruett-Miller, Shondra M., Kalathur, Ravi C., Haferlach, Claudia, Kern, Wolfgang, Paietta, Elisabeth, Thomas, Paul G., Babu, M. Madan, Loughran, Thomas P., Iacobucci, Ilaria, Haferlach, Torsten, Mullighan, Charles G
Publicado 2022