Characterization of Stem-like Circulating Tumor Cells in Pancreatic Cancer

por Zhu, Lei, Hissa, Barbara, Győrffy, Balázs, Jann, Johann-Christoph, Yang, Cui, Reissfelder, Christoph, Schölch, Sebastian
Publicado 2020

Deep sequencing of bone marrow microenvironments of patients with del(5q) myelodysplastic syndrome reveals imprints of antigenic selection as well as generation of novel T-cell clu...

por Mährle, Thorben, Akyüz, Nuray, Fuchs, Pim, Bonzanni, Nicola, Simnica, Donjete, Germing, Ulrich, Asemissen, Anne Marie, Jann, Johann Christoph, Nolte, Florian, Hofmann, Wolf-Karsten, Nowak, Daniel, Binder, Mascha
Publicado 2019

Bone marrow derived stromal cells from myelodysplastic syndromes are altered but not clonally mutated in vivo

por Jann, Johann-Christoph, Mossner, Maximilian, Riabov, Vladimir, Altrock, Eva, Schmitt, Nanni, Flach, Johanna, Xu, Qingyu, Nowak, Verena, Obländer, Julia, Palme, Iris, Weimer, Nadine, Streuer, Alexander, Jawhar, Ahmed, Darwich, Ali, Jawhar, Mohammad, Metzgeroth, Georgia, Nolte, Florian, Hofmann, Wolf-Karsten, Nowak, Daniel
Publicado 2021

Replication stress signaling is a therapeutic target in myelodysplastic syndromes with splicing factor mutations

por Flach, Johanna, Jann, Johann-Christoph, Knaflic, Antje, Riabov, Vladimir, Streuer, Alexander, Altrock, Eva, Xu, Qingyu, Schmitt, Nanni, Obländer, Julia, Nowak, Verena, Danner, Justine, Mehralivand, Arwin, Hofmann, Franziska, Palme, Iris, Jawhar, Ahmed, Wuchter, Patrick, Metzgeroth, Georgia, Nolte, Florian, Hofmann, Wolf-Karsten, Nowak, Daniel
Publicado 2020

Significant improvement of bone marrow-derived MSC expansion from MDS patients by defined xeno-free medium

por Altrock, Eva, Sens-Albert, Carla, Hofmann, Franziska, Riabov, Vladimir, Schmitt, Nanni, Xu, Qingyu, Jann, Johann-Christoph, Rapp, Felicitas, Steiner, Laurenz, Streuer, Alexander, Nowak, Verena, Obländer, Julia, Weimer, Nadine, Palme, Iris, Göl, Melda, Darwich, Ali, Wuchter, Patrick, Metzgeroth, Georgia, Jawhar, Mohamad, Hofmann, Wolf-Karsten, Nowak, Daniel
Publicado 2023

Accurate quantification of chromosomal lesions via short tandem repeat analysis using minimal amounts of DNA

por Jann, Johann-Christoph, Nowak, Daniel, Nolte, Florian, Fey, Stephanie, Nowak, Verena, Obländer, Julia, Pressler, Jovita, Palme, Iris, Xanthopoulos, Christina, Fabarius, Alice, Platzbecker, Uwe, Giagounidis, Aristoteles, Götze, Katharina, Letsch, Anne, Haase, Detlef, Schlenk, Richard, Bug, Gesine, Lübbert, Michael, Ganser, Arnold, Germing, Ulrich, Haferlach, Claudia, Hofmann, Wolf-Karsten, Mossner, Maximilian
Publicado 2017

Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics

por Velten, Lars, Story, Benjamin A., Hernández-Malmierca, Pablo, Raffel, Simon, Leonce, Daniel R., Milbank, Jennifer, Paulsen, Malte, Demir, Aykut, Szu-Tu, Chelsea, Frömel, Robert, Lutz, Christoph, Nowak, Daniel, Jann, Johann-Christoph, Pabst, Caroline, Boch, Tobias, Hofmann, Wolf-Karsten, Müller-Tidow, Carsten, Trumpp, Andreas, Haas, Simon, Steinmetz, Lars M.
Publicado 2021

Functional analysis of structural variants in single cells using Strand-seq

por Jeong, Hyobin, Grimes, Karen, Rauwolf, Kerstin K., Bruch, Peter-Martin, Rausch, Tobias, Hasenfeld, Patrick, Benito, Eva, Roider, Tobias, Sabarinathan, Radhakrishnan, Porubsky, David, Herbst, Sophie A., Erarslan-Uysal, Büşra, Jann, Johann-Christoph, Marschall, Tobias, Nowak, Daniel, Bourquin, Jean-Pierre, Kulozik, Andreas E., Dietrich, Sascha, Bornhauser, Beat, Sanders, Ashley D., Korbel, Jan O.
Publicado 2022

Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states

por Triana, Sergio, Vonficht, Dominik, Jopp-Saile, Lea, Raffel, Simon, Lutz, Raphael, Leonce, Daniel, Antes, Magdalena, Hernández-Malmierca, Pablo, Ordoñez-Rueda, Diana, Ramasz, Beáta, Boch, Tobias, Jann, Johann-Christoph, Nowak, Daniel, Hofmann, Wolf-Karsten, Müller-Tidow, Carsten, Hübschmann, Daniel, Alexandrov, Theodore, Benes, Vladimir, Trumpp, Andreas, Paulsen, Malte, Velten, Lars, Haas, Simon
Publicado 2021

Genome-wide DNA methylation analysis pre- and post-lenalidomide treatment in patients with myelodysplastic syndrome with isolated deletion (5q)

por Hecht, Anna, Meyer, Julia A., Jann, Johann-Christoph, Sockel, Katja, Giagounidis, Aristoteles, Götze, Katharina S., Letsch, Anne, Haase, Detlef, Schlenk, Richard F., Haferlach, Torsten, Schafhausen, Philippe, Bug, Gesine, Lübbert, Michael, Thol, Felicitas, Büsche, Guntram, Schuler, Esther, Nowak, Verena, Obländer, Julia, Fey, Stephanie, Müller, Nadine, Metzgeroth, Georgia, Hofmann, Wolf-Karsten, Germing, Ulrich, Nolte, Florian, Reinwald, Mark, Nowak, Daniel
Publicado 2021

Preclinical evaluation of eltrombopag in a PDX model of myelodysplastic syndromes

por Schmitt, Nanni, Jann, Johann-Christoph, Altrock, Eva, Flach, Johanna, Danner, Justine, Uhlig, Stefanie, Streuer, Alexander, Knaflic, Antje, Riabov, Vladimir, Xu, Qingyu, Mehralivand, Arwin, Palme, Iris, Nowak, Verena, Obländer, Julia, Weimer, Nadine, Haselmann, Verena, Jawhar, Ahmed, Darwich, Ali, Weis, Cleo-Aron, Marx, Alexander, Steiner, Laurenz, Jawhar, Mohamad, Metzgeroth, Georgia, Boch, Tobias, Nolte, Florian, Hofmann, Wolf-Karsten, Nowak, Daniel
Publicado 2021

Inhibition of lysyl oxidases synergizes with 5-azacytidine to restore erythropoiesis in myelodysplastic and myeloid malignancies

por Xu, Qingyu, Streuer, Alexander, Jann, Johann-Christoph, Altrock, Eva, Schmitt, Nanni, Flach, Johanna, Sens-Albert, Carla, Rapp, Felicitas, Wolf, Julia, Nowak, Verena, Weimer, Nadine, Obländer, Julia, Palme, Iris, Kuzina, Mariia, Jawhar, Ahmed, Darwich, Ali, Weis, Cleo-Aron, Marx, Alexander, Wuchter, Patrick, Costina, Victor, Jäger, Evelyn, Sperk, Elena, Neumaier, Michael, Fabarius, Alice, Metzgeroth, Georgia, Nolte, Florian, Steiner, Laurenz, Levkin, Pavel A., Jawhar, Mohamad, Hofmann, Wolf-Karsten, Riabov, Vladimir, Nowak, Daniel
Publicado 2023