Characterization of human Fc alpha receptor transgenic mice: comparison of CD89 expression and antibody-dependent tumor killing between mouse strains

por Stip, Marjolein C., Jansen, J. H. Marco, Nederend, Maaike, Tsioumpekou, Maria, Evers, Mitchell, Olofsen, Patricia A., Meyer-Wentrup, Friederike, Leusen, Jeanette H. W.
Publicado 2023

Effective, Long-Term, Neutrophil Depletion Using a Murinized Anti-Ly-6G 1A8 Antibody

por Olofsen, Patricia A., Stip, Marjolein C., Jansen, J. H. Marco, Chan, Chilam, Nederend, Maaike, Tieland, Ralph G., Tsioumpekou, Maria, Leusen, Jeanette H. W.
Publicado 2022

Sialic Acids on Tumor Cells Modulate IgA Therapy by Neutrophils via Inhibitory Receptors Siglec-7 and Siglec-9

por Chan, Chilam, Lustig, Marta, Jansen, J. H. Marco, Garcia Villagrasa, Laura, Raymakers, Leon, Daamen, Lois A., Valerius, Thomas, van Tetering, Geert, Leusen, Jeanette H. W.
Publicado 2023

Potent Fc Receptor Signaling by IgA Leads to Superior Killing of Cancer Cells by Neutrophils Compared to IgG

por Brandsma, Arianne M., Bondza, Sina, Evers, Mitchell, Koutstaal, Rosanne, Nederend, Maaike, Jansen, J. H. Marco, Rösner, Thies, Valerius, Thomas, Leusen, Jeanette H. W., ten Broeke, Toine
Publicado 2019

Improved in vivo anti-tumor effects of IgA-Her2 antibodies through half-life extension and serum exposure enhancement by FcRn targeting

por Meyer, Saskia, Nederend, Maaike, Jansen, J.H. Marco, Reiding, Karli R., Jacobino, Shamir R., Meeldijk, Jan, Bovenschen, Niels, Wuhrer, Manfred, Valerius, Thomas, Ubink, Ruud, Boross, Peter, Rouwendal, Gerard, Leusen, Jeanette H.W.
Publicado 2015

Bovine IgG Prevents Experimental Infection With RSV and Facilitates Human T Cell Responses to RSV

por Nederend, Maaike, van Stigt, Arthur H., Jansen, J. H. Marco, Jacobino, Shamir R., Brugman, Sylvia, de Haan, Cornelis A. M., Bont, Louis J., van Neerven, R. J. Joost, Leusen, Jeanette H. W.
Publicado 2020

Novel chimerized IgA CD20 antibodies: Improving neutrophil activation against CD20-positive malignancies

por Evers, Mitchell, Ten Broeke, Toine, Jansen, J.H. Marco, Nederend, Maaike, Hamdan, Firas, Reiding, Karli R., Meyer, Saskia, Moerer, Petra, Brinkman, Iris, Rösner, Thies, Lebbink, Robert Jan, Valerius, Thomas, Leusen, Jeanette H.W.
Publicado 2020

Reformatting palivizumab and motavizumab from IgG to human IgA impairs their efficacy against RSV infection in vitro and in vivo

por Jacobino, Shamir R., Nederend, Maaike, Reijneveld, J. Frederiek, Augustijn, Daan, Jansen, J. H. Marco, Meeldijk, Jan, Reiding, Karli R., Wuhrer, Manfred, Coenjaerts, Frank E. J., Hack, C. Erik, Bont, Louis J., Leusen, Jeanette H. W.
Publicado 2018

Enhancement of epidermal growth factor receptor antibody tumor immunotherapy by glutaminyl cyclase inhibition to interfere with CD47/signal regulatory protein alpha interactions

por Baumann, Niklas, Rösner, Thies, Jansen, J. H. Marco, Chan, Chilam, Marie Eichholz, Klara, Klausz, Katja, Winterberg, Dorothee, Müller, Kristina, Humpe, Andreas, Burger, Renate, Peipp, Matthias, Schewe, Denis M., Kellner, Christian, Leusen, Jeanette H. W., Valerius, Thomas
Publicado 2021

Disruption of the sialic acid/Siglec-9 axis improves antibody-mediated neutrophil cytotoxicity towards tumor cells

por Lustig, Marta, Chan, Chilam, Jansen, J. H. Marco, Bräutigam, Maria, Kölling, Max A., Gehlert, Carina Lynn, Baumann, Niklas, Mester, Simone, Foss, Stian, Andersen, Jan Terje, Bastian, Lorenz, Sondermann, Peter, Peipp, Matthias, Burger, Renate, Leusen, Jeanette H. W., Valerius, Thomas
Publicado 2023

MCL-1 is required throughout B-cell development and its loss sensitizes specific B-cell subsets to inhibition of BCL-2 or BCL-XL

por Vikström, Ingela B, Slomp, Anne, Carrington, Emma M, Moesbergen, Laura M, Chang, Catherine, Kelly, Gemma L, Glaser, Stefan P, Jansen, J H Marco, Leusen, Jeanette H W, Strasser, Andreas, Huang, David C S, Lew, Andrew M, Peperzak, Victor, Tarlinton, David M
Publicado 2016

Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and target for cancer immunotherapy

por Logtenberg, Meike E. W., Jansen, J. H. Marco, Raaben, Matthijs, Toebes, Mireille, Franke, Katka, Brandsma, Arianne M., Matlung, Hanke L., Fauster, Astrid, Gomez-Eerland, Raquel, Bakker, Noor A. M., van der Schot, Simone, Marijt, Koen A., Verdoes, Martijn, Haanen, John B. A. G., van den Berg, Joost H., Neefjes, Jacques, van den Berg, Timo K., Brummelkamp, Thijn R., Leusen, Jeanette H. W., Scheeren, Ferenc A., Schumacher, Ton N.
Publicado 2019