Increased MAPK1/3 Phosphorylation in Luminal Breast Cancer Related with PIK3CA Hotspot Mutations and Prognosis

por Ramirez-Ardila, Diana, Timmermans, A. Mieke, Helmijr, Jean A., Martens, John W.M., Berns, Els M.J.J., Jansen, Maurice P.H.M.
Publicado 2017

Detection of oncogenic mutations in paired circulating tumor DNA and circulating tumor cells in patients with hepatocellular carcinoma

por Ge, Zhouhong, Helmijr, Jean C.A., Jansen, Maurice P.H.M., Boor, Patrick P.C., Noordam, Lisanne, Peppelenbosch, Maikel, Kwekkeboom, Jaap, Kraan, Jaco, Sprengers, Dave
Publicado 2021

High ctDNA molecule numbers relate with poor outcome in advanced ER+, HER2− postmenopausal breast cancer patients treated with everolimus and exemestane

por Kruger, Dinja T., Jansen, Maurice P.H.M., Konings, Inge R.H.M., Dercksen, Wouter M., Jager, Agnes, Oulad Hadj, Jamal, Sleijfer, Stefan, Martens, John W.M., Boven, Epie
Publicado 2020

Mutation Analysis of Pancreatic Juice and Plasma for the Detection of Pancreatic Cancer

por Levink, Iris J. M., Jansen, Maurice P. H. M., Azmani, Zakia, van IJcken, Wilfred, van Marion, Ronald, Peppelenbosch, Maikel P., Cahen, Djuna L., Fuhler, Gwenny M., Bruno, Marco J.
Publicado 2023

Application of circulating tumor DNA in prospective clinical oncology trials – standardization of preanalytical conditions

por van Dessel, Lisanne F., Beije, Nick, Helmijr, Jean C.A., Vitale, Silvia R., Kraan, Jaco, Look, Maxime P., de Wit, Ronald, Sleijfer, Stefan, Jansen, Maurice P.H.M., Martens, John W.M., Lolkema, Martijn P.
Publicado 2017

Liquid biopsy in esophageal cancer: a case report of false-positive circulating tumor DNA detection due to clonal hematopoiesis

por Spoor, Jonathan, Eyck, Ben M., Atmodimedjo, Peggy N., Jansen, Maurice P. H. M., Helmijr, Jean C. A., Martens, John W. M., van der Wilk, Berend J., van Lanschot, J. Jan B., Dinjens, Winand N. M.
Publicado 2021

The prognostic and predictive value of ESR1 fusion gene transcripts in primary breast cancer

por Vitale, Silvia R., Ruigrok-Ritstier, Kirsten, Timmermans, A. Mieke, Foekens, Renée, Trapman-Jansen, Anita M. A. C., Beaufort, Corine M., Vigneri, Paolo, Sleijfer, Stefan, Martens, John W. M., Sieuwerts, Anieta M., Jansen, Maurice P. H. M.
Publicado 2022

High‐throughput isolation of circulating tumor DNA: a comparison of automated platforms

por van Dessel, Lisanne F., Vitale, Silvia R., Helmijr, Jean C. A., Wilting, Saskia M., van der Vlugt‐Daane, Michelle, Oomen‐de Hoop, Esther, Sleijfer, Stefan, Martens, John W. M., Jansen, Maurice P. H. M., Lolkema, Martijn P.
Publicado 2018

Somatic Tumor Mutations Detected by Targeted Next Generation Sequencing in Minute Amounts of Serum-Derived Cell-Free DNA

por Weerts, Marjolein J. A., van Marion, Ronald, Helmijr, Jean C. A., Beaufort, Corine M., Krol, Niels M. G., Trapman-Jansen, Anita M. A. C., Dinjens, Winand N. M., Sleijfer, Stefan, Jansen, Maurice P. H. M., Martens, John W. M.
Publicado 2017

Comparison of variant allele frequency and number of mutant molecules as units of measurement for circulating tumor DNA

por Bos, Manouk K., Nasserinejad, Kazem, Jansen, Maurice P. H. M., Angus, Lindsay, Atmodimedjo, Peggy N., de Jonge, Evert, Dinjens, Winand N. M., van Schaik, Ron H. N., Del Re, Marzia, Dubbink, Hendrikus J., Sleijfer, Stefan, Martens, John W. M.
Publicado 2020

Machine learning-based somatic variant calling in cell-free DNA of metastatic breast cancer patients using large NGS panels

por Jongbloed, Elisabeth M., Jansen, Maurice P. H. M., de Weerd, Vanja, Helmijr, Jean A., Beaufort, Corine M., Reinders, Marcel J. T., van Marion, Ronald, van IJcken, Wilfred F. J., Sonke, Gabe S., Konings, Inge R., Jager, Agnes, Martens, John W. M., Wilting, Saskia M., Makrodimitris, Stavros
Publicado 2023

TP53 Mutations in Serum Circulating Cell-Free Tumor DNA As Longitudinal Biomarker for High-Grade Serous Ovarian Cancer

por Vitale, Silvia R., Groenendijk, Floris H., van Marion, Ronald, Beaufort, Corine M., Helmijr, Jean C., Jan Dubbink, Hendrikus, N. M. Dinjens, Winand, Ewing-Graham, Patricia C., Smolders, Ramon, van Doorn, Helena C., Boere, Ingrid A., Berns, Els M. J. J., Helleman, Jozien, Jansen, Maurice P. H. M.
Publicado 2020

Detection of tumor-derived extracellular vesicles in plasma from patients with solid cancer

por Vitale, Silvia R., Helmijr, Jean A., Gerritsen, Marjolein, Coban, Hicret, van Dessel, Lisanne F., Beije, Nick, van der Vlugt-Daane, Michelle, Vigneri, Paolo, Sieuwerts, Anieta M., Dits, Natasja, van Royen, Martin E., Jenster, Guido, Sleijfer, Stefan, Lolkema, Martijn, Martens, John W. M., Jansen, Maurice P. H. M.
Publicado 2021

Optimizing Nanopore sequencing-based detection of structural variants enables individualized circulating tumor DNA-based disease monitoring in cancer patients

por Valle-Inclan, Jose Espejo, Stangl, Christina, de Jong, Anouk C., van Dessel, Lisanne F., van Roosmalen, Markus J., Helmijr, Jean C. A., Renkens, Ivo, Janssen, Roel, de Blank, Sam, de Witte, Chris J., Martens, John W. M., Jansen, Maurice P. H. M., Lolkema, Martijn P., Kloosterman, Wigard P.
Publicado 2021

The COMPLETE trial: HolistiC early respOnse assessMent for oroPharyngeaL cancEr paTiEnts; Protocol for an observational study

por Verduijn, Gerda M, Capala, Marta E, Sijtsema, Nienke D, Lauwers, Iris, Hernandez Tamames, Juan A, Heemsbergen, Wilma D, Sewnaik, Aniel, Hardillo, Jose A, Mast, Hetty, van Norden, Yvette, Jansen, Maurice P H M, van der Lugt, Aad, van Gent, Dik C, Hoogeman, Mischa S, Mostert, Bianca, Petit, Steven F
Publicado 2022

Estrogen receptor mutations and splice variants determined in liquid biopsies from metastatic breast cancer patients

por Beije, Nick, Sieuwerts, Anieta M., Kraan, Jaco, Van, Ngoc M., Onstenk, Wendy, Vitale, Silvia R., van der Vlugt‐Daane, Michelle, Dirix, Luc Y., Brouwer, Anja, Hamberg, Paul, de Jongh, Felix E., Jager, Agnes, Seynaeve, Caroline M., Jansen, Maurice P. H. M., Foekens, John A., Martens, John W. M., Sleijfer, Stefan
Publicado 2017

RAS and BRAF mutations in cell‐free DNA are predictive for outcome of cetuximab monotherapy in patients with tissue‐tested RAS wild‐type advanced colorectal cancer

por van Helden, Erik J., Angus, Lindsay, Menke‐van der Houven van Oordt, C. Willemien, Heideman, Daniëlle A. M., Boon, Eline, van Es, Suzanne C., Radema, Sandra A., van Herpen, Carla M. L., de Groot, Derk Jan A., de Vries, Elisabeth G. E., Jansen, Maurice P. H. M., Sleijfer, Stefan, Verheul, Henk M. W.
Publicado 2019

An 8-gene mRNA expression profile in circulating tumor cells predicts response to aromatase inhibitors in metastatic breast cancer patients

por Reijm, Esther A., Sieuwerts, Anieta M., Smid, Marcel, Vries, Joan Bolt-de, Mostert, Bianca, Onstenk, Wendy, Peeters, Dieter, Dirix, Luc Y., Seynaeve, Caroline M., Jager, Agnes, de Jongh, Felix E., Hamberg, Paul, van Galen, Anne, Kraan, Jaco, Jansen, Maurice P. H. M., Gratama, Jan W., Foekens, John A., Martens, John W. M., Berns, Els M. J. J., Sleijfer, Stefan
Publicado 2016

Cell-free DNA mutations as biomarkers in breast cancer patients receiving tamoxifen

por Jansen, Maurice P.H.M., Martens, John W.M., Helmijr, Jean C.A., Beaufort, Corine M., van Marion, Ronald, Krol, Niels M.G., Monkhorst, Kim, Trapman-Jansen, Anita M.A.C., Meijer-van Gelder, Marion E., Weerts, Marjolein J.A., Ramirez-Ardila, Diana E., Jan Dubbink, Hendrikus, Foekens, John A., Sleijfer, Stefan, Berns, Els M.J.J.
Publicado 2016