Current Landscape of Targeted Therapies for Hormone-Receptor Positive, HER2 Negative Metastatic Breast Cancer

por Ballinger, Tarah J., Meier, Jason B., Jansen, Valerie M.
Publicado 2018

Thermal proteome profiling of breast cancer cells reveals proteasomal activation by CDK4/6 inhibitor palbociclib

por Miettinen, Teemu P, Peltier, Julien, Härtlova, Anetta, Gierliński, Marek, Jansen, Valerie M, Trost, Matthias, Björklund, Mikael
Publicado 2018

Clinical Response to Seribantumab, an Anti–Human Epidermal Growth Factor Receptor-3 Immunoglobulin 2 Monoclonal Antibody, in a Patient With Metastatic Pancreatic Ductal Adenocarcin...

por Thavaneswaran, Subotheni, Chan, Wei Yen, Asghari, Ray, Grady, John P., Deegan, Maegan, Jansen, Valerie M., Thomas, David M.
Publicado 2022

SETD2 loss sensitizes cells to PI3Kβ and AKT inhibition

por Terzo, Esteban A., Lim, Aaron R., Chytil, Anna, Chiang, Yun Chen, Farmer, Leah, Gessner, Kathryn H., Walker, Cheryl Lyn, Jansen, Valerie M., Rathmell, W. Kimryn
Publicado 2019

Correction: SETD2 loss sensitizes cells to PI3Kβ and AKT inhibition

por Terzo, Esteban A., Lim, Aaron R., Chytil, Anna, Chiang, Yun Chen, Farmer, Leah, Gessner, Kathryn H., Walker, Cheryl Lyn, Jansen, Valerie M., Rathmell, W. Kimryn
Publicado 2019

Combined inhibition of PIM and CDK4/6 suppresses both mTOR signaling and Rb phosphorylation and potentiates PI3K inhibition in cancer cells

por Litchfield, Lacey M., Boehnke, Karsten, Brahmachary, Manisha, Mur, Cecilia, Bi, Chen, Stephens, Jennifer R., Sauder, J. Michael, Gutiérrez, Sonia M., McNulty, Ann M., Ye, Xiang S., Wu, Wenjuan, Lallena, María José, Gong, Xueqian, Merzoug, Farhana F., Jansen, Valerie M., Buchanan, Sean G.
Publicado 2020

Proline rich 11 (PRR11) overexpression amplifies PI3K signaling and promotes antiestrogen resistance in breast cancer

por Lee, Kyung-min, Guerrero-Zotano, Angel L., Servetto, Alberto, Sudhan, Dhivya R., Lin, Chang-Ching, Formisano, Luigi, Jansen, Valerie M., González-Ericsson, Paula, Sanders, Melinda E., Stricker, Thomas P., Raj, Ganesh, Dean, Kevin M., Fiolka, Reto, Cantley, Lewis C., Hanker, Ariella B., Arteaga, Carlos L.
Publicado 2020

Aberrant FGFR signaling mediates resistance to CDK4/6 inhibitors in ER+ breast cancer

por Formisano, Luigi, Lu, Yao, Servetto, Alberto, Hanker, Ariella B., Jansen, Valerie M., Bauer, Joshua A., Sudhan, Dhivya R., Guerrero-Zotano, Angel L., Croessmann, Sarah, Guo, Yan, Ericsson, Paula Gonzalez, Lee, Kyung-min, Nixon, Mellissa J., Schwarz, Luis J., Sanders, Melinda E., Dugger, Teresa C., Cruz, Marcelo Rocha, Behdad, Amir, Cristofanilli, Massimo, Bardia, Aditya, O’Shaughnessy, Joyce, Nagy, Rebecca J., Lanman, Richard B., Solovieff, Nadia, He, Wei, Miller, Michelle, Su, Fei, Shyr, Yu, Mayer, Ingrid A., Balko, Justin M., Arteaga, Carlos L.
Publicado 2019