Catalytic Inhibitors of Topoisomerase II Differently Modulate the Toxicity of Anthracyclines in Cardiac and Cancer Cells

por Vavrova, Anna, Jansova, Hana, Mackova, Eliska, Machacek, Miloslav, Haskova, Pavlina, Tichotova, Lucie, Sterba, Martin, Simunek, Tomas
Publicado 2013

Examination of diverse iron-chelating agents for the protection of differentiated PC12 cells against oxidative injury induced by 6-hydroxydopamine and dopamine

por Hašková, Pavlína, Applová, Lenka, Jansová, Hana, Homola, Pavel, Franz, Katherine J., Vávrová, Kateřina, Roh, Jaroslav, Šimůnek, Tomáš
Publicado 2022

Quantitative Analysis of the Anti-Proliferative Activity of Combinations of Selected Iron-Chelating Agents and Clinically Used Anti-Neoplastic Drugs

por Potuckova, Eliska, Jansova, Hana, Machacek, Miloslav, Vavrova, Anna, Haskova, Pavlina, Tichotova, Lucie, Richardson, Vera, Kalinowski, Danuta S., Richardson, Des R., Simunek, Tomas
Publicado 2014

In Vitro Characterization of the Pharmacological Properties of the Anti-Cancer Chelator, Bp4eT, and Its Phase I Metabolites

por Potůčková, Eliška, Roh, Jaroslav, Macháček, Miloslav, Sahni, Sumit, Stariat, Ján, Šesták, Vít, Jansová, Hana, Hašková, Pavlína, Jirkovská, Anna, Vávrová, Kateřina, Kovaříková, Petra, Kalinowski, Danuta S., Richardson, Des R., Šimůnek, Tomáš
Publicado 2015

Novel and potent anti-tumor and anti-metastatic di-2-pyridylketone thiosemicarbazones demonstrate marked differences in pharmacology between the first and second generation lead ag...

por Sestak, Vit, Stariat, Jan, Cermanova, Jolana, Potuckova, Eliska, Chladek, Jaroslav, Roh, Jaroslav, Bures, Jan, Jansova, Hana, Prusa, Petr, Sterba, Martin, Micuda, Stanislav, Simunek, Tomas, Kalinowski, Danuta S., Richardson, Des R., Kovarikova, Petra
Publicado 2015

Development of water-soluble prodrugs of the bisdioxopiperazine topoisomerase IIβ inhibitor ICRF-193 as potential cardioprotective agents against anthracycline cardiotoxicity

por Bavlovič Piskáčková, Hana, Jansová, Hana, Kubeš, Jan, Karabanovich, Galina, Váňová, Nela, Kollárová-Brázdová, Petra, Melnikova, Iuliia, Jirkovská, Anna, Lenčová-Popelová, Olga, Chládek, Jaroslav, Roh, Jaroslav, Šimůnek, Tomáš, Štěrba, Martin, Štěrbová-Kovaříková, Petra
Publicado 2021

Structure-Activity Relationships of Novel Salicylaldehyde Isonicotinoyl Hydrazone (SIH) Analogs: Iron Chelation, Anti-Oxidant and Cytotoxic Properties

por Potůčková, Eliška, Hrušková, Kateřina, Bureš, Jan, Kovaříková, Petra, Špirková, Iva A., Pravdíková, Kateřina, Kolbabová, Lucie, Hergeselová, Tereza, Hašková, Pavlína, Jansová, Hana, Macháček, Miloslav, Jirkovská, Anna, Richardson, Vera, Lane, Darius J. R., Kalinowski, Danuta S., Richardson, Des R., Vávrová, Kateřina, Šimůnek, Tomáš
Publicado 2014