S-Glutathionylation-Controlled Apoptosis of Lung Epithelial Cells; Potential Implications for Lung Fibrosis

por Corteselli, Elizabeth, Aboushousha, Reem, Janssen-Heininger, Yvonne
Publicado 2022

Endoplasmic reticulum stress and glutathione therapeutics in chronic lung diseases

por Janssen-Heininger, Yvonne, Reynaert, Niki L., van der Vliet, Albert, Anathy, Vikas
Publicado 2020

Differential Requirement for c-Jun N-terminal Kinase 1 in Lung Inflammation and Host Defense

por Van der Velden, Jos, Janssen-Heininger, Yvonne M. W., Mandalapu, Sivanarayna, Scheller, Erich V., Kolls, Jay K., Alcorn, John F.
Publicado 2012

Oxidation of peroxiredoxin-4 induces oligomerization and promotes interaction with proteins governing protein folding and endoplasmic reticulum stress

por Elko, Evan A., Manuel, Allison M., White, Sheryl, Zito, Ester, van der Vliet, Albert, Anathy, Vikas, Janssen-Heininger, Yvonne M.W.
Publicado 2021

Identification of DUOX1-dependent redox signaling through protein S-glutathionylation in airway epithelial cells()

por Hristova, Milena, Veith, Carmen, Habibovic, Aida, Lam, Ying-Wai, Deng, Bin, Geiszt, Miklos, Janssen-Heininger, Yvonne M.W., van der Vliet, Albert
Publicado 2014

Redox amplification of apoptosis by caspase-dependent cleavage of glutaredoxin 1 and S-glutathionylation of Fas

por Anathy, Vikas, Aesif, Scott W., Guala, Amy S., Havermans, Marije, Reynaert, Niki L., Ho, Ye-Shih, Budd, Ralph C., Janssen-Heininger, Yvonne M.W.
Publicado 2009

The Effect of Flavored E-cigarettes on Murine Allergic Airways Disease

por Chapman, David G., Casey, Dylan T., Ather, Jennifer L., Aliyeva, Minara, Daphtary, Nirav, Lahue, Karolyn G., van der Velden, Jos L., Janssen-Heininger, Yvonne M. W., Irvin, Charles G.
Publicado 2019

Airway epithelial specific deletion of Jun-N-terminal kinase 1 attenuates pulmonary fibrosis in two independent mouse models

por van der Velden, Jos L., Alcorn, John F., Chapman, David G., Lundblad, Lennart K. A., Irvin, Charles G., Davis, Roger J., Butnor, Kelly, Janssen-Heininger, Yvonne M. W.
Publicado 2020

The redox mechanism for vascular barrier dysfunction associated with metabolic disorders: Glutathionylation of Rac1 in endothelial cells

por Han, Jingyan, Weisbrod, Robert M., Shao, Di, Watanabe, Yosuke, Yin, Xiaoyan, Bachschmid, Markus M., Seta, Francesca, Janssen-Heininger, Yvonne M.W., Matsui, Reiko, Zang, Mengwei, Hamburg, Naomi M., Cohen, Richard A.
Publicado 2016

SPLUNC1 regulation in airway epithelial cells: role of toll-like receptor 2 signaling

por Chu, Hong Wei, Gally, Fabienne, Thaikoottathil, Jyoti, Janssen-Heininger, Yvonne M, Wu, Qun, Zhang, Gongyi, Reisdorph, Nichole, Case, Stephanie, Minor, Maisha, Smith, Sean, Jiang, Di, Michels, Nicole, Simon, Glenn, Martin, Richard J
Publicado 2010

Macrophage-intrinsic DUOX1 contributes to type 2 inflammation and mucus metaplasia during allergic airway disease

por Morris, Carolyn R., Habibovic, Aida, Dustin, Christopher M., Schiffers, Caspar, Lin, Miao-Chong, Ather, Jennifer L., Janssen-Heininger, Yvonne M.W., Poynter, Matthew E., Utermohlen, Olaf, Krönke, Martin, van der Vliet, Albert
Publicado 2022

Glutathione S-transferases and their implications in the lung diseases asthma and chronic obstructive pulmonary disease: Early life susceptibility?

por van de Wetering, Cheryl, Elko, Evan, Berg, Marijn, Schiffers, Caspar H.J., Stylianidis, Vasili, van den Berge, Maarten, Nawijn, Martijn C., Wouters, Emiel F.M., Janssen-Heininger, Yvonne M.W., Reynaert, Niki L.
Publicado 2021

Glutaredoxin attenuates glutathione levels via deglutathionylation of Otub1 and subsequent destabilization of system x(C)(−)

por Aboushousha, Reem, van der Velden, Jos, Hamilton, Nicholas, Peng, Zhihua, MacPherson, Maximilian, Erickson, Cuixia, White, Sheryl, Wouters, Emiel F. M., Reynaert, Niki L., Seward, David J., Li, Jianing, Janssen-Heininger, Yvonne M. W.
Publicado 2023

Mitochondrial ROS induced by chronic ethanol exposure promote hyper-activation of the NLRP3 inflammasome()

por Hoyt, Laura R., Randall, Matthew J., Ather, Jennifer L., DePuccio, Daniel P., Landry, Christopher C., Qian, Xi, Janssen-Heininger, Yvonne M., van der Vliet, Albert, Dixon, Anne E., Amiel, Eyal, Poynter, Matthew E.
Publicado 2017

Glutaredoxin deficiency promotes activation of the transforming growth factor beta pathway in airway epithelial cells, in association with fibrotic airway remodeling

por Chia, Shi B., Nolin, James D., Aboushousha, Reem, Erikson, Cuixia, Irvin, Charles G., Poynter, Matthew E., van der Velden, Jos, Taatjes, Douglas J., van der Vliet, Albert, Anathy, Vikas, Janssen-Heininger, Yvonne M.W.
Publicado 2020

Structural and functional fine mapping of cysteines in mammalian glutaredoxin reveal their differential oxidation susceptibility

por Corteselli, Elizabeth M., Sharafi, Mona, Hondal, Robert, MacPherson, Maximilian, White, Sheryl, Lam, Ying-Wai, Gold, Clarissa, Manuel, Allison M., van der Vliet, Albert, Schneebeli, Severin T., Anathy, Vikas, Li, Jianing, Janssen-Heininger, Yvonne M. W.
Publicado 2023

Dysregulated Redox Regulation Contributes to Nuclear EGFR Localization and Pathogenicity in Lung Cancer

por Little, Andrew C., Hristova, Milena, van Lith, Loes, Schiffers, Caspar, Dustin, Christopher M., Habibovic, Aida, Danyal, Karamatullah, Heppner, David E., Lin, Miao-Chong J., van der Velden, Jos, Janssen-Heininger, Yvonne M., van der Vliet, Albert
Publicado 2019

Inhibition of PDIA3 in club cells attenuates osteopontin production and lung fibrosis

por Kumar, Amit, Elko, Evan, Bruno, Sierra R, Mark, Zoe F, Chamberlain, Nicolas, Mihavics, Bethany Korwin, Chandrasekaran, Ravishankar, Walzer, Joseph, Ruban, Mona, Gold, Clarissa, Lam, Ying Wai, Ghandikota, Sudhir, Jegga, Anil G, Gomez, Jose L, Janssen-Heininger, Yvonne MW, Anathy, Vikas
Publicado 2022

Glutathione S-transferase pi modulates NF-κB activation and pro-inflammatory responses in lung epithelial cells

por Jones, Jane T., Qian, Xi, van der Velden, Jos L.J., Chia, Shi Biao, McMillan, David H., Flemer, Stevenson, Hoffman, Sidra M., Lahue, Karolyn G., Schneider, Robert W., Nolin, James D., Anathy, Vikas, van der Vliet, Albert, Townsend, Danyelle M., Tew, Kenneth D., Janssen-Heininger, Yvonne M.W.
Publicado 2016

JNK inhibition reduces lung remodeling and pulmonary fibrotic systemic markers

por van der Velden, Jos L. J., Ye, Ying, Nolin, James D., Hoffman, Sidra M., Chapman, David G., Lahue, Karolyn G., Abdalla, Sarah, Chen, Peng, Liu, Yong, Bennett, Brydon, Khalil, Nasreen, Sutherland, Donna, Smith, William, Horan, Gerald, Assaf, Mahmoud, Horowitz, Zebulun, Chopra, Rajesh, Stevens, Randall M., Palmisano, Maria, Janssen-Heininger, Yvonne M. W., Schafer, Peter H.
Publicado 2016