A home run for human NaCT/SLC13A5/INDY: cryo-EM structure and homology model to predict transport mechanisms, inhibitor interactions and mutational defects

por Jaramillo-Martinez, Valeria, Ganapathy, Vadivel, Urbatsch, Ina L.
Publicado 2021

Drosophila INDY and Mammalian INDY: Major Differences in Transport Mechanism and Structural Features despite Mostly Similar Biological Functions

por Jaramillo-Martinez, Valeria, Sivaprakasam, Sathish, Ganapathy, Vadivel, Urbatsch, Ina L.
Publicado 2021

Sigma Receptors: Novel Regulators of Iron/Heme Homeostasis and Ferroptosis

por Nguyen, Nhi T., Jaramillo-Martinez, Valeria, Mathew, Marilyn, Suresh, Varshini V., Sivaprakasam, Sathish, Bhutia, Yangzom D., Ganapathy, Vadivel
Publicado 2023

Lipid environment determines the drug-stimulated ATPase activity of P-glycoprotein

por Tran, Nghi N. B., Bui, A. T. A., Jaramillo-Martinez, Valeria, Weber, Joachim, Zhang, Qinghai, Urbatsch, Ina L.
Publicado 2023

Functional analysis of a species-specific inhibitor selective for human Na(+)-coupled citrate transporter (NaCT/SLC13A5/mINDY)

por Higuchi, Kei, Kopel, Jonathan J., Sivaprakasam, Sathish, Jaramillo-Martinez, Valeria, Sutton, R. Bryan, Urbatsch, Ina L., Ganapathy, Vadivel
Publicado 2020

An Unbound Proline-Rich Signaling Peptide Frequently Samples Cis Conformations in Gaussian Accelerated Molecular Dynamics Simulations

por Alcantara, Juan, Stix, Robyn, Huang, Katherine, Connor, Acadia, East, Ray, Jaramillo-Martinez, Valeria, Stollar, Elliott J., Ball, K. Aurelia
Publicado 2021

Potent Inhibition of Macropinocytosis by Niclosamide in Cancer Cells: A Novel Mechanism for the Anticancer Efficacy for the Antihelminthic

por Sennoune, Souad R., Nandagopal, Gunadharini Dharmalingam, Ramachandran, Sabarish, Mathew, Marilyn, Sivaprakasam, Sathish, Jaramillo-Martinez, Valeria, Bhutia, Yangzom D., Ganapathy, Vadivel
Publicado 2023

How a highly acidic SH3 domain folds in the absence of its charged peptide target

por Jaramillo‐Martinez, Valeria, Dominguez, Matthew J., Bell, Gemma M., Souness, Megan E., Carhart, Anna H., Cuibus, M. Adriana, Masoumzadeh, Elahe, Lantz, Benjamin J., Adkins, Aaron J., Latham, Michael P., Ball, K. Aurelia, Stollar, Elliott J.
Publicado 2023