HER2 regulates HIF-2α and drives an increased hypoxic response in breast cancer

por Jarman, Edward J., Ward, Carol, Turnbull, Arran K., Martinez-Perez, Carlos, Meehan, James, Xintaropoulou, Chrysi, Sims, Andrew H., Langdon, Simon P.
Publicado 2019

Antitumour activity of the novel flavonoid Oncamex in preclinical breast cancer models

por Martínez-Pérez, Carlos, Ward, Carol, Turnbull, Arran K, Mullen, Peter, Cook, Graeme, Meehan, James, Jarman, Edward J, Thomson, Patrick IT, Campbell, Colin J, McPhail, Donald, Harrison, David J, Langdon, Simon P
Publicado 2016

Inhibition of pH regulation as a therapeutic strategy in hypoxic human breast cancer cells

por Meehan, James, Ward, Carol, Turnbull, Arran, Bukowski-Wills, Jimi, Finch, Andrew J., Jarman, Edward J., Xintaropoulou, Chrysi, Martinez-Perez, Carlos, Gray, Mark, Pearson, Matthew, Mullen, Peter, Supuran, Claudiu T., Carta, Fabrizio, Harrison, David J., Kunkler, Ian H., Langdon, Simon P.
Publicado 2017

DKK1 drives immune suppressive phenotypes in intrahepatic cholangiocarcinoma and can be targeted with anti‐DKK1 therapeutic DKN‐01

por Jarman, Edward J., Horcas‐Lopez, Marta, Waddell, Scott H., MacMaster, Stephanie, Gournopanos, Konstantinos, Soong, Daniel Y. H., Musialik, Kamila I., Tsokkou, Panagiota, Ng, Minn‐E, Cambridge, William A., Wilson, David H., Kagey, Michael H., Newman, Walter, Pollard, Jeffrey W., Boulter, Luke
Publicado 2022

Evaluation of carbonic anhydrase IX as a therapeutic target for inhibition of breast cancer invasion and metastasis using a series of in vitro breast cancer models

por Ward, Carol, Meehan, James, Mullen, Peter, Supuran, Claudiu, Dixon, J. Michael, Thomas, Jeremy S., Winum, Jean-Yves, Lambin, Philippe, Dubois, Ludwig, Pavathaneni, Nanda-Kumar, Jarman, Edward J., Renshaw, Lorna, Um, InHwa, Kay, Charlene, Harrison, David J., Kunkler, Ian H., Langdon, Simon P.
Publicado 2015

A TGFβ-ECM-Integrin signalling axis drives structural reconfiguration of the bile duct to promote polycystic liver disease

por Waddell, Scott H, Yao, Yuelin, Olaizola, Paula, Walker, Alexander, Jarman, Edward J, Gournopanos, Konstantinos, Gradinaru, Andreea, Christodoulou, Ersi, Gautier, Philippe, Boerrigter, Melissa M, Cadamuro, Massimiliano, Fabris, Luca, Drenth, Joost PH, Kendall, Timothy J, Banales, Jesus M, Khamseh, Ava, Mill, Pleasantine, Boulter, Luke
Publicado 2023

In Vivo Modeling of Patient Genetic Heterogeneity Identifies New Ways to Target Cholangiocarcinoma

por Younger, Nicholas T., Wilson, Mollie L., Martinez Lyons, Anabel, Jarman, Edward J., Meynert, Alison M., Grimes, Graeme R., Gournopanos, Konstantinos, Waddell, Scott H., Tennant, Peter A., Wilson, David H., Guest, Rachel V., Wigmore, Stephen J., Acosta, Juan Carlos, Kendall, Timothy J., Taylor, Martin S., Sproul, Duncan, Mill, Pleasantine, Boulter, Luke
Publicado 2022

A sensitive and affordable multiplex RT-qPCR assay for SARS-CoV-2 detection

por Reijns, Martin A. M., Thompson, Louise, Acosta, Juan Carlos, Black, Holly A., Sanchez-Luque, Francisco J., Diamond, Austin, Parry, David A., Daniels, Alison, O'Shea, Marie, Uggenti, Carolina, Sanchez, Maria C., O'Callaghan, Alan, McNab, Michelle L. L., Adamowicz, Martyna, Friman, Elias T., Hurd, Toby, Jarman, Edward J., Chee, Frederic Li Mow, Rainger, Jacqueline K., Walker, Marion, Drake, Camilla, Longman, Dasa, Mordstein, Christine, Warlow, Sophie J., McKay, Stewart, Slater, Louise, Ansari, Morad, Tomlinson, Ian P. M., Moore, David, Wilkinson, Nadine, Shepherd, Jill, Templeton, Kate, Johannessen, Ingolfur, Tait-Burkard, Christine, Haas, Jürgen G., Gilbert, Nick, Adams, Ian R., Jackson, Andrew P.
Publicado 2020