2831. Efficacy and Safety of Gepotidacin for Uncomplicated Urinary Tract Infection: Pooled Subgroup Analyses of the EAGLE-2 and EAGLE-3 Randomized Phase 3 Trials

por Hooton, Thomas M, Perry, Caroline R, Janmohamed, Salim, Sheets, Amanda, Dennison, Jeremy, Millns, Helen, Jarvis, Emily, Huang, Chun
Publicado 2023

Quantum Chemistry–Machine Learning Approach for Predicting Properties of Lewis Acid–Lewis Base Adducts

por Huynh, Hieu, Kelly, Thomas J., Vu, Linh, Hoang, Tung, Nguyen, Phuc An, Le, Tu C., Jarvis, Emily A., Phan, Hung
Publicado 2023

2837. Impact of Regulatory Guidelines on Therapeutic, Clinical, and Microbiological Success Rates in Uncomplicated Urinary Tract Infection: Results from a Two Phase 3 Randomized Co...

por Wagenlehner, Florian, Perry, Caroline R, Hooton, Thomas M, Scangarella-Oman, Nicole E, Millns, Helen, Jarvis, Emily, Dennison, Jeremy, Sheets, Amanda, Janmohamed, Salim
Publicado 2023

2832. Gepotidacin Efficacy in E. coli Drug-Resistant Phenotypes: A Pooled Analysis of the EAGLE-2 and EAGLE-3 Randomized Controlled Trials in Uncomplicated Urinary Tract Infection

por Hooton, Thomas M, Perry, Caroline R, Janmohamed, Salim, Sheets, Amanda, Dennison, Jeremy, Millns, Helen, Jarvis, Emily, Scangarella-Oman, Nicole E, Huang, Chun
Publicado 2023

Mass spectrometry detection of inhaled drug in distal fibrotic lung

por Mikolasch, Theresia A., Oballa, Eunice, Vahdati-Bolouri, Mitra, Jarvis, Emily, Cui, Yi, Cahn, Anthony, Terry, Rebecca L., Sahota, Jagdeep, Thakrar, Ricky, Marshall, Peter, Porter, Joanna C.
Publicado 2022

P31 Efficacy and safety of oral gepotidacin in the treatment of uncomplicated urinary tract infection: results of two randomized, multicentre Phase 3 trials (EAGLE-2 and EAGLE-3)

por Wagenlehner, Florian, Perry, Caroline R, Hooton, Thomas M, Scangarella-Oman, Nicole E, Millns, Helen, (Ed) Feng, Hwa-ping, Powell, Marcy, Jarvis, Emily, Dennison, Jeremy, Sheets, Amanda, Butler, Deborah, Breton, John, Janmohamed, Salim
Publicado 2023

An Inhaled PI3Kδ Inhibitor Improves Recovery in Acutely Exacerbating COPD Patients: A Randomized Trial

por Cahn, Anthony, Hamblin, J Nicole, Robertson, Jon, Begg, Malcolm, Jarvis, Emily, Wilson, Robert, Dear, Gordon, Leemereise, Claudia, Cui, Yi, Mizuma, Maki, Montembault, Mickael, Van Holsbeke, Cedric, Vos, Wim, De Backer, Wilfried, De Backer, Jan, Hessel, Edith M
Publicado 2021

Use of autologous (99m)Technetium-labelled neutrophils to quantify lung neutrophil clearance in COPD

por Tregay, Nicola, Begg, Malcolm, Cahn, Anthony, Farahi, Neda, Povey, Kathryn, Madhavan, Sujith, Simmonds, Rosalind, Gillett, Daniel, Solanki, Chandra, Wong, Anna, Maison, Joanna, Lennon, Mark, Bradley, Glyn, Jarvis, Emily, de Groot, Marius, Wilson, Fred, Babar, Judith, Peters, A Michael, Hessel, Edith M, Chilvers, Edwin R
Publicado 2019

Exploring PI3Kδ Molecular Pathways in Stable COPD and Following an Acute Exacerbation, Two Randomized Controlled Trials

por Begg, Malcolm, Hamblin, J Nicole, Jarvis, Emily, Bradley, Glyn, Mark, Stephen, Michalovich, David, Lennon, Mark, Wajdner, Hannah E, Amour, Augustin, Wilson, Robert, Saunders, Ken, Tanaka, Rikako, Arai, Saki, Tang, Teresa, Van Holsbeke, Cedric, De Backer, Jan, Vos, Wim, Titlestad, Ingrid L, FitzGerald, J Mark, Killian, Kieran, Bourbeau, Jean, Poirier, Claude, Maltais, François, Cahn, Anthony, Hessel, Edith M
Publicado 2021

A randomised trial of anti-GM-CSF otilimab in severe COVID-19 pneumonia (OSCAR)

por Patel, Jatin, Bass, Damon, Beishuizen, Albertus, Bocca Ruiz, Xavier, Boughanmi, Hatem, Cahn, Anthony, Colombo, Hugo, Criner, Gerard J., Davy, Katherine, de-Miguel-Díez, Javier, Doreski, Pablo A., Fernandes, Sofia, François, Bruno, Gupta, Anubha, Hanrott, Kate, Hatlen, Timothy, Inman, Dave, Isaacs, John D., Jarvis, Emily, Kostina, Natalia, Kropotina, Tatiana, Lacherade, Jean-Claude, Lakshminarayanan, Divya, Martinez-Ayala, Pedro, McEvoy, Charlene, Meziani, Ferhat, Monchi, Mehran, Mukherjee, Sumanta, Muñoz-Bermúdez, Rosana, Neisen, Jessica, O'Shea, Ciara, Plantefeve, Gaëtan, Schifano, Lorrie, Schwab, Lee E., Shahid, Zainab, Shirano, Michinori, Smith, Julia E., Sprinz, Eduardo, Summers, Charlotte, Terzi, Nicolas, Tidswell, Mark A., Trefilova, Yuliya, Williamson, Russell, Wyncoll, Duncan, Layton, Mark
Publicado 2023