Statistical Challenges when Analyzing SARS-CoV-2 RNA Measurements Below the Assay Limit of Quantification in COVID-19 Clinical Trials

por Moser, Carlee B, Chew, Kara W, Giganti, Mark J, Li, Jonathan Z, Aga, Evgenia, Ritz, Justin, Greninger, Alexander L, Javan, Arzhang Cyrus, Daar, Eric S, Currier, Judith S, Eron, Joseph J, Smith, Davey M, Hughes, Michael D
Publicado 2023

Comparative Pharmacokinetics of Tixagevimab/Cilgavimab (AZD7442) Administered Intravenously Versus Intramuscularly in Symptomatic SARS‐CoV‐2 Infection

por Bender Ignacio, Rachel A., Wohl, David A., Arends, Rosalin, Pilla Reddy, Venkatesh, Mu, Ying, Javan, Arzhang Cyrus, Hughes, Michael D., Eron, Joseph J., Currier, Judith S., Smith, Davey, Chew, Kara W., Gibbs, Michael, Fletcher, Courtney V.
Publicado 2022

878. Association between Anterior Nasal and Plasma SARS-CoV-2 RNA Levels and Hospitalization or Death for Non-Hospitalized Adults with Mild-to-Moderate COVID-19

por Giganti, Mark, Chew, Kara W, Eron, Joseph J, Li, Jonathan Z, Pinilla, Mauricio, Moser, Carlee, Javan, Arzhang Cyrus, Fischer, William A, Klekotka, Paul, Margolis, David A, Wohl, David A, Coombs, Robert, Daar, Eric S, Smith, Davey M, Hughes, Michael D, Currier, Judith S
Publicado 2022

881. Nasal and Plasma SARS-CoV-2 RNA Levels Predict Timing of Symptom Resolution in the ACTIV-2 Trial of Non-hospitalized Adults with COVID-19

por Li, Yijia, Harrison, Linda J, Chew, Kara W, Eron, Joseph J, Daar, Eric S, Wohl, David A, Wu, Ryan, Moser, Carlee, Ritz, Justin, Giganti, Mark, Javan, Arzhang Cyrus, Coombs, Robert, Hughes, Michael D, Currier, Judith S, Smith, Davey M, Li, Jonathan Z
Publicado 2022

LB2. Safety and Efficacy of Combination SARS-CoV-2 Monoclonal Neutralizing Antibodies (mAb) BRII-196 and BRII-198 in Non-Hospitalized COVID-19 Patients

por Evering, Teresa H, Giganti, Mark, Chew, Kara W, Hughes, Michael, Moser, Carlee, Wohl, David Alain, Currier, Judith, Eron, Joseph J, Javan, Arzhang, Margolis, David A, Zhu, Qing, D’Andrea, Ulises, Hoover, Keila, Mocherla, Bharat R, Fletcher, Courtney, Li, Jonathan, Smith, Davey, Daar, Eric
Publicado 2021

Predictors of SARS-CoV-2 RNA From Nasopharyngeal Swabs and Concordance With Other Compartments in Nonhospitalized Adults With Mild to Moderate COVID-19

por Moser, Carlee, Li, Jonathan Z, Eron, Joseph J, Aga, Evgenia, Daar, Eric S, Wohl, David A, Coombs, Robert W, Javan, Arzhang Cyrus, Bender Ignacio, Rachel A, Jagannathan, Prasanna, Ritz, Justin, Sieg, Scott F, Parikh, Urvi M, Hughes, Michael D, Currier, Judith S, Smith, Davey M, Chew, Kara W
Publicado 2022

Safety and efficacy of inhaled interferon-β1a (SNG001) in adults with mild-to-moderate COVID-19: a randomized, controlled, phase II trial

por Jagannathan, Prasanna, Chew, Kara W., Giganti, Mark J., Hughes, Michael D., Moser, Carlee, Main, Mark J., Monk, Phillip D., Javan, Arzhang Cyrus, Li, Jonathan Z., Fletcher, Courtney V., McCarthy, Caitlyn, Wohl, David A., Daar, Eric S., Eron, Joseph J., Currier, Judith S., Singh, Upinder, Smith, Davey M., Fischer, William
Publicado 2023

Bamlanivimab reduces nasopharyngeal SARS-CoV-2 RNA levels but not symptom duration in non-hospitalized adults with COVID-19: A Phase 2 Randomized Clinical Trial

por Chew, Kara W., Moser, Carlee, Daar, Eric S., Wohl, David A., Li, Jonathan Z., Coombs, Robert, Ritz, Justin, Giganti, Mark, Javan, Arzhang Cyrus, Li, Yijia, Malvestutto, Carlos, Klekotka, Paul, Price, Karen, Nirula, Ajay, Fischer, William, Bala, Veenu, Ribeiro, Ruy M., Perelson, Alan S., Fletcher, Courtney V., Eron, Joseph J., Currier, Judith S., Hughes, Michael D., Smith, Davey M.
Publicado 2021

Safety and Efficacy of Combined Tixagevimab and Cilgavimab Administered Intramuscularly or Intravenously in Nonhospitalized Patients With COVID-19: 2 Randomized Clinical Trials

por Bender Ignacio, Rachel A., Chew, Kara W., Moser, Carlee, Currier, Judith S., Eron, Joseph J., Javan, Arzhang Cyrus, Giganti, Mark J., Aga, Evgenia, Gibbs, Michael, Tchouakam Kouekam, Hervé, Johnsson, Eva, Esser, Mark T., Hoover, Keila, Neytman, Gene, Newell, Matthew, Daar, Eric S., Fischer, William, Fletcher, Courtney V., Li, Jonathan Z., Greninger, Alexander L., Coombs, Robert W., Hughes, Michael D., Smith, Davey, Wohl, David Alain
Publicado 2023

Monoclonal antibody treatment drives rapid culture conversion in SARS-CoV-2 infection

por Boucau, Julie, Chew, Kara W., Choudhary, Manish, Deo, Rinki, Regan, James, Flynn, James P., Crain, Charles R., Hughes, Michael D., Ritz, Justin, Moser, Carlee, Dragavon, Joan A., Javan, Arzhang C., Nirula, Ajay, Klekotka, Paul, Greninger, Alexander L., Coombs, Robert W., Fischer, William A, Daar, Eric S., Wohl, David A., Eron, Joseph J., Currier, Judith S., Smith, Davey M, Li, Jonathan Z., Barczak, Amy K.
Publicado 2021

Monoclonal antibody treatment drives rapid culture conversion in SARS-CoV-2 infection

por Boucau, Julie, Chew, Kara W., Choudhary, Manish C., Deo, Rinki, Regan, James, Flynn, James P., Crain, Charles R., Hughes, Michael D., Ritz, Justin, Moser, Carlee, Dragavon, Joan A., Javan, Arzhang C., Nirula, Ajay, Klekotka, Paul, Greninger, Alexander L., Coombs, Robert W., Fischer, William A., Daar, Eric S., Wohl, David A., Eron, Joseph J., Currier, Judith S., Smith, Davey M., Li, Jonathan Z., Barczak, Amy K.
Publicado 2022

Antiviral and clinical activity of bamlanivimab in a randomized trial of non-hospitalized adults with COVID-19

por Chew, Kara W., Moser, Carlee, Daar, Eric S., Wohl, David A., Li, Jonathan Z., Coombs, Robert W., Ritz, Justin, Giganti, Mark, Javan, Arzhang Cyrus, Li, Yijia, Choudhary, Manish C., Deo, Rinki, Malvestutto, Carlos, Klekotka, Paul, Price, Karen, Nirula, Ajay, Fischer, William, Bala, Veenu, Ribeiro, Ruy M., Perelson, Alan S., Fletcher, Courtney V., Eron, Joseph J., Currier, Judith S., Hughes, Michael D., Smith, Davey M.
Publicado 2022

Publisher Correction: Antiviral and clinical activity of bamlanivimab in a randomized trial of non-hospitalized adults with COVID-19

por Chew, Kara W., Moser, Carlee, Daar, Eric S., Wohl, David A., Li, Jonathan Z., Coombs, Robert W., Ritz, Justin, Giganti, Mark, Javan, Arzhang Cyrus, Li, Yijia, Choudhary, Manish C., Deo, Rinki, Malvestutto, Carlos, Klekotka, Paul, Price, Karen, Nirula, Ajay, Fischer, William, Bala, Veenu, Ribeiro, Ruy M., Perelson, Alan S., Fletcher, Courtney V., Eron, Joseph J., Currier, Judith S., Hughes, Michael D., Smith, Davey M.
Publicado 2023