Probing BoNT/A Protease Exosites: Implications for Inhibitor Design and Light Chain Longevity

por Xue, Song, Javor, Sacha, Hixon, Mark S., Janda, Kim D.
Publicado 2014

An Immunomodulatory Peptide Dendrimer Inspired from Glatiramer Acetate

por Erzina, Dina, Capecchi, Alice, Javor, Sacha, Reymond, Jean‐Louis
Publicado 2021

Dipropylamine for 9-Fluorenylmethyloxycarbonyl (Fmoc) Deprotection with Reduced Aspartimide Formation in Solid-Phase Peptide Synthesis

por Personne, Hippolyte, Siriwardena, Thissa N., Javor, Sacha, Reymond, Jean-Louis
Publicado 2023

Synergistic Effect of Propidium Iodide and Small Molecule Antibiotics with the Antimicrobial Peptide Dendrimer G3KL against Gram-Negative Bacteria

por Gan, Bee-Ha, Cai, Xingguang, Javor, Sacha, Köhler, Thilo, Reymond, Jean-Louis
Publicado 2020

The antibacterial activity of peptide dendrimers and polymyxin B increases sharply above pH 7.4

por Cai, Xingguang, Javor, Sacha, Gan, Bee Ha, Köhler, Thilo, Reymond, Jean-Louis
Publicado 2021

Stereorandomization as a Method to Probe Peptide Bioactivity

por Siriwardena, Thissa N., Gan, Bee-Ha, Köhler, Thilo, van Delden, Christian, Javor, Sacha, Reymond, Jean-Louis
Publicado 2021

An intrinsically disordered antimicrobial peptide dendrimer from stereorandomized virtual screening

por Cai, Xingguang, Orsi, Markus, Capecchi, Alice, Köhler, Thilo, van Delden, Christian, Javor, Sacha, Reymond, Jean-Louis
Publicado 2022

Novel Human Butyrylcholinesterase Variants: Toward Organophosphonate Detoxication

por Dwyer, Mary, Javor, Sacha, Ryan, Daniel A., Smith, Emily M., Wang, Beilin, Zhang, Jun, Cashman, John R.
Publicado 2014

Pyrazolyl-pyrimidones inhibit the function of human solute carrier protein SLC11A2 (hDMT1) by metal chelation

por Poirier, Marion, Pujol-Giménez, Jonai, Manatschal, Cristina, Bühlmann, Sven, Embaby, Ahmed, Javor, Sacha, Hediger, Matthias A., Reymond, Jean-Louis
Publicado 2020

A mixed chirality α-helix in a stapled bicyclic and a linear antimicrobial peptide revealed by X-ray crystallography

por Baeriswyl, Stéphane, Personne, Hippolyte, Di Bonaventura, Ivan, Köhler, Thilo, van Delden, Christian, Stocker, Achim, Javor, Sacha, Reymond, Jean-Louis
Publicado 2021

To Fold or Not to Fold: Diastereomeric Optimization of an α-Helical Antimicrobial Peptide

por Personne, Hippolyte, Paschoud, Thierry, Fulgencio, Sofia, Baeriswyl, Stéphane, Köhler, Thilo, van Delden, Christian, Stocker, Achim, Javor, Sacha, Reymond, Jean-Louis
Publicado 2023

Inhibitors of Human Divalent Metal Transporters DMT1 (SLC11A2) and ZIP8 (SLC39A8) from a GDB‐17 Fragment Library

por Pujol‐Giménez, Jonai, Poirier, Marion, Bühlmann, Sven, Schuppisser, Céline, Bhardwaj, Rajesh, Awale, Mahendra, Visini, Ricardo, Javor, Sacha, Hediger, Matthias A., Reymond, Jean‐Louis
Publicado 2021

Chemical space guided discovery of antimicrobial bridged bicyclic peptides against Pseudomonas aeruginosa and its biofilms

por Di Bonaventura, Ivan, Jin, Xian, Visini, Ricardo, Probst, Daniel, Javor, Sacha, Gan, Bee-Ha, Michaud, Gaëlle, Natalello, Antonino, Doglia, Silvia Maria, Köhler, Thilo, van Delden, Christian, Stocker, Achim, Darbre, Tamis, Reymond, Jean-Louis
Publicado 2017