Implementation of Endogenous and Exogenous Mesenchymal Progenitor Cells for Skeletal Tissue Regeneration and Repair

por Desai, Salomi, Jayasuriya, Chathuraka T.
Publicado 2020

Post-Traumatic Osteoarthritis Assessment in Emerging and Advanced Pre-Clinical Meniscus Repair Strategies: A Review

por Trivedi, Jay, Betensky, Daniel, Desai, Salomi, Jayasuriya, Chathuraka T.
Publicado 2021

Matrilin-3 Induction of IL-1 receptor antagonist Is required for up-regulating collagen II and aggrecan and down-regulating ADAMTS-5 gene expression

por Jayasuriya, Chathuraka T, Goldring, Mary B, Terek, Richard, Chen, Qian
Publicado 2012

Suppressing Chondrocyte Hypertrophy to Build Better Cartilage

por Shigley, Christian, Trivedi, Jay, Meghani, Ozair, Owens, Brett D., Jayasuriya, Chathuraka T.
Publicado 2023

MON-262 Aggrecan Is Required for Chondrocyte Differentiation in ATDC5 Chondroprogenitor Cells

por Hodax, Juanita, Quintos, Jose Bernardo, Gruppuso, Philip, Chen, Qian, Jayasuriya, Chathuraka
Publicado 2019

SHP-2 deletion in CD4Cre expressing chondrocyte precursors leads to tumor development with wrist tropism

por McNamara, Jeffrey T., Huntington, Kelsey E., Borys, Samantha, Jayasuriya, Chathuraka T., Brossay, Laurent
Publicado 2021

Senescent Tissue-Resident Mesenchymal Stromal Cells Are an Internal Source of Inflammation in Human Osteoarthritic Cartilage

por Liu, Wenguang, Brodsky, Alexander S., Feng, Meng, Liu, Yajun, Ding, Jing, Jayasuriya, Chathuraka T., Chen, Qian
Publicado 2021

Molecular characterization of mesenchymal stem cells in human osteoarthritis cartilage reveals contribution to the OA phenotype

por Jayasuriya, Chathuraka T., Hu, Nan, Li, Jing, Lemme, Nicholas, Terek, Richard, Ehrlich, Michael G., Chen, Qian
Publicado 2018

Aggrecan is required for chondrocyte differentiation in ATDC5 chondroprogenitor cells

por Hodax, Juanita K., Quintos, Jose Bernardo, Gruppuso, Philip A., Chen, Qian, Desai, Salomi, Jayasuriya, Chathuraka T.
Publicado 2019

Matrilin-3 Chondrodysplasia Mutations Cause Attenuated Chondrogenesis, Premature Hypertrophy and Aberrant Response to TGF-β in Chondroprogenitor Cells

por Jayasuriya, Chathuraka T., Zhou, Fiona H., Pei, Ming, Wang, Zhengke, Lemme, Nicholas J., Haines, Paul, Chen, Qian
Publicado 2014

Chondrogenic induction of human osteoarthritic cartilage-derived mesenchymal stem cells activates mineralization and hypertrophic and osteogenic gene expression through a mechanomi...

por Hu, Nan, Gao, Yun, Jayasuriya, Chathuraka T., Liu, Wenguang, Du, Heng, Ding, Jing, Feng, Meng, Chen, Qian
Publicado 2019

Blockade of hypoxia-induced CXCR4 with AMD3100 inhibits production of OA-associated catabolic mediators IL-1β and MMP-13

por Li, Pengcui, Deng, Jin, Wei, Xiaochun, Jayasuriya, Chathuraka T., Zhou, Jingming, Chen, Qian, Zhang, Jianzhong, Wei, Lei, Wei, Fangyuan
Publicado 2016

Ptpn11 Deletion in CD4(+) Cells Does Not Affect T Cell Development and Functions but Causes Cartilage Tumors in a T Cell-Independent Manner

por Miah, S. M. Shahjahan, Jayasuriya, Chathuraka T., Salter, Alexander I., Reilly, Emma C., Fugere, Céline, Yang, Wentian, Chen, Qian, Brossay, Laurent
Publicado 2017

Distal-Less Homeobox 5 Is a Therapeutic Target for Attenuating Hypertrophy and Apoptosis of Mesenchymal Progenitor Cells

por Twomey-Kozak, John, Desai, Salomi, Liu, Wenguang, Li, Neill Y., Lemme, Nicholas, Chen, Qian, Owens, Brett D., Jayasuriya, Chathuraka T.
Publicado 2020

Stable human cartilage progenitor cell line stimulates healing of meniscal tears and attenuates post-traumatic osteoarthritis

por Desai, Salomi, Dooner, Mark, Newberry, Jake, Twomey-Kozak, John, Molino, Janine, Trivedi, Jay, Patel, Jay M., Owens, Brett D., Jayasuriya, Chathuraka T.
Publicado 2022

Human Cartilage‐Derived Progenitors Resist Terminal Differentiation and Require CXCR4 Activation to Successfully Bridge Meniscus Tissue Tears

por Jayasuriya, Chathuraka T., Twomey‐Kozak, John, Newberry, Jake, Desai, Salomi, Feltman, Peter, Franco, Jonathan R., Li, Neill, Terek, Richard, Ehrlich, Michael G., Owens, Brett D.
Publicado 2018

Deficient Mechanical Activation of Anabolic Transcripts and Post-Traumatic Cartilage Degeneration in Matrilin-1 Knockout Mice

por Chen, Yupeng, Cossman, Jack, Jayasuriya, Chathuraka T., Li, Xin, Guan, Yingjie, Fonseca, Vera, Yang, Kun, Charbonneau, Cherie, Yu, Hongchuan, Kanbe, Katsuaki, Ma, Peter, Darling, Eric, Chen, Qian
Publicado 2016