Codon usage bias controls mRNA and protein abundance in trypanosomatids

por Jeacock, Laura, Faria, Joana, Horn, David
Publicado 2018

Inducible high-efficiency CRISPR-Cas9-targeted gene editing and precision base editing in African trypanosomes

por Rico, Eva, Jeacock, Laura, Kovářová, Julie, Horn, David
Publicado 2018

Aquaglyceroporin-null trypanosomes display glycerol transport defects and respiratory-inhibitor sensitivity

por Jeacock, Laura, Baker, Nicola, Wiedemar, Natalie, Mäser, Pascal, Horn, David
Publicado 2017

Pentamidine Is Not a Permeant but a Nanomolar Inhibitor of the Trypanosoma brucei Aquaglyceroporin-2

por Song, Jie, Baker, Nicola, Rothert, Monja, Henke, Björn, Jeacock, Laura, Horn, David, Beitz, Eric
Publicado 2016

Repositioning of a Diaminothiazole Series Confirmed to Target the Cyclin-Dependent Kinase CRK12 for Use in the Treatment of African Animal Trypanosomiasis

por Smith, Alasdair, Wall, Richard J., Patterson, Stephen, Rowan, Tim, Rico Vidal, Eva, Stojanovski, Laste, Huggett, Margaret, Hampton, Shahienaz E., Thomas, Michael G., Corpas Lopez, Victoriano, Gillingwater, Kirsten, Duke, Jeff, Napier, Grant, Peter, Rose, Vitouley, Hervé S., Harrison, Justin R., Milne, Rachel, Jeacock, Laura, Baker, Nicola, Davis, Susan H., Simeons, Frederick, Riley, Jennifer, Horn, David, Brun, Reto, Zuccotto, Fabio, Witty, Michael J, Wyllie, Susan, Read, Kevin D., Gilbert, Ian H.
Publicado 2022

Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition

por Wyllie, Susan, Brand, Stephen, Thomas, Michael, De Rycker, Manu, Chung, Chun-wa, Pena, Imanol, Bingham, Ryan P., Bueren-Calabuig, Juan A., Cantizani, Juan, Cebrian, David, Craggs, Peter D., Ferguson, Liam, Goswami, Panchali, Hobrath, Judith, Howe, Jonathan, Jeacock, Laura, Ko, Eun-Jung, Korczynska, Justyna, MacLean, Lorna, Manthri, Sujatha, Martinez, Maria S., Mata-Cantero, Lydia, Moniz, Sonia, Nühs, Andrea, Osuna-Cabello, Maria, Pinto, Erika, Riley, Jennifer, Robinson, Sharon, Rowland, Paul, Simeons, Frederick R. C., Shishikura, Yoko, Spinks, Daniel, Stojanovski, Laste, Thomas, John, Thompson, Stephen, Viayna Gaza, Elisabet, Wall, Richard J., Zuccotto, Fabio, Horn, David, Ferguson, Michael A. J., Fairlamb, Alan H., Fiandor, Jose M., Martin, Julio, Gray, David W., Miles, Timothy J., Gilbert, Ian H., Read, Kevin D., Marco, Maria, Wyatt, Paul G.
Publicado 2019