Delta1 Expression, Cell Cycle Exit, and Commitment to a Specific Secretory Fate Coincide within a Few Hours in the Mouse Intestinal Stem Cell System

por Stamataki, Despina, Holder, Maxine, Hodgetts, Christine, Jeffery, Rosemary, Nye, Emma, Spencer-Dene, Bradley, Winton, Douglas J., Lewis, Julian
Publicado 2011

Bone Marrow Cells in Murine Colitis: Multi-Signal Analysis Confirms Pericryptal Myofibroblast Engraftment without Epithelial Involvement

por Lee, Chung-Yin, Jeffery, Rosemary, Hutchinson, Gillian, Alison, Malcolm R., Poulsom, Richard, Wright, Nicholas A., Otto, William R.
Publicado 2011

Role of Reactive Oxygen Species in the Abrogation of Oxaliplatin Activity by Cetuximab in Colorectal Cancer

por Santoro, Valeria, Jia, Ruochen, Thompson, Hannah, Nijhuis, Anke, Jeffery, Rosemary, Kiakos, Konstantinos, Silver, Andrew R., Hartley, John A., Hochhauser, Daniel
Publicado 2015

Epithelial down‐regulation of the miR‐200 family in fibrostenosing Crohn's disease is associated with features of epithelial to mesenchymal transition

por Mehta, Shameer J., Lewis, Amy, Nijhuis, Anke, Jeffery, Rosemary, Biancheri, Paolo, Di Sabatino, Antonio, Feakins, Roger, Silver, Andrew, Lindsay, James Oliver
Publicado 2018

Epidermal growth factor attenuates tubular necrosis following mercuric chloride damage by regeneration of indigenous, not bone marrow-derived cells

por Yen, Tzung-Hai, Alison, Malcolm R, Goodlad, Robert A, Otto, William R, Jeffery, Rosemary, Cook, H Terence, Wright, Nicholas A, Poulsom, Richard
Publicado 2015

Familial adenomatous patients with desmoid tumours show increased expression of miR-34a in serum and high levels in tumours

por Walton, Sarah-Jane, Lewis, Amy, Jeffery, Rosemary, Thompson, Hannah, Feakins, Roger, Giannoulatou, Eleni, Yau, Christopher, Lindsay, James O., Clark, Susan K., Silver, Andrew
Publicado 2016

Severe polyposis in Apc(1322T) mice is associated with submaximal Wnt signalling and increased expression of the stem cell marker Lgr5

por Lewis, Annabelle, Segditsas, Stefania, Deheragoda, Maesha, Pollard, Patrick, Jeffery, Rosemary, Nye, Emma, Lockstone, Helen, Davis, Hayley, Clark, Susan, Stamp, Gordon, Poulsom, Richard, Wright, Nicholas, Tomlinson, Ian
Publicado 2010

The miR-200 family is increased in dysplastic lesions in ulcerative colitis patients

por Lewis, Amy, Felice, Carla, Kumagai, Tomoko, Lai, Cecilia, Singh, Kriti, Jeffery, Rosemary R., Feakins, Roger, Giannoulatou, Eleni, Armuzzi, Alessandro, Jawad, Noor, Lindsay, James O., Silver, Andrew
Publicado 2017

Putative direct and indirect Wnt targets identified through consistent gene expression changes in APC-mutant intestinal adenomas from humans and mice

por Segditsas, Stefania, Sieber, Oliver, Deheragoda, Maesha, East, Phil, Rowan, Andrew, Jeffery, Rosemary, Nye, Emma, Clark, Susan, Spencer-Dene, Bradley, Stamp, Gordon, Poulsom, Richard, Suraweera, Nirosha, Silver, Andrew, Ilyas, Mohammad, Tomlinson, Ian
Publicado 2008

Low-dose TNF augments fracture healing in normal and osteoporotic bone by up-regulating the innate immune response

por Chan, James K, Glass, Graeme E, Ersek, Adel, Freidin, Andrew, Williams, Garry A, Gowers, Kate, Espirito Santo, Ana I, Jeffery, Rosemary, Otto, William R, Poulsom, Richard, Feldmann, Marc, Rankin, Sara M, Horwood, Nicole J, Nanchahal, Jagdeep
Publicado 2015

A basal gradient of Wnt and stem-cell number influences regional tumour distribution in human and mouse intestinal tracts

por Leedham, Simon J, Rodenas-Cuadrado, Pedro, Howarth, Kimberley, Lewis, Annabelle, Mallappa, Sreelakshmi, Segditsas, Stefania, Davis, Hayley, Jeffery, Rosemary, Rodriguez-Justo, Manuel, Keshav, Satish, Travis, Simon P L, Graham, Trevor A, East, James, Clark, Susan, Tomlinson, Ian P M
Publicado 2013

Bone morphogenetic protein and Notch signalling crosstalk in poor‐prognosis, mesenchymal‐subtype colorectal cancer

por Irshad, Shazia, Bansal, Mukesh, Guarnieri, Paolo, Davis, Hayley, Al Haj Zen, Ayman, Baran, Brygida, Pinna, Claudia Maria Assunta, Rahman, Haseeb, Biswas, Sujata, Bardella, Chiara, Jeffery, Rosemary, Wang, Lai Mun, East, James Edward, Tomlinson, Ian, Lewis, Annabelle, Leedham, Simon John
Publicado 2017

Remodelling of microRNAs in colorectal cancer by hypoxia alters metabolism profiles and 5-fluorouracil resistance

por Nijhuis, Anke, Thompson, Hannah, Adam, Julie, Parker, Alexandra, Gammon, Luke, Lewis, Amy, Bundy, Jacob G., Soga, Tomoyoshi, Jalaly, Aisha, Propper, David, Jeffery, Rosemary, Suraweera, Nirosha, McDonald, Sarah, Thaha, Mohamed A., Feakins, Roger, Lowe, Robert, Bishop, Cleo L., Silver, Andrew
Publicado 2017

The stem cell organisation, and the proliferative and gene expression profile of Barrett's epithelium, replicates pyloric-type gastric glands

por Lavery, Danielle L, Nicholson, Anna M, Poulsom, Richard, Jeffery, Rosemary, Hussain, Alia, Gay, Laura J, Jankowski, Janusz A, Zeki, Sebastian S, Barr, Hugh, Harrison, Rebecca, Going, James, Kadirkamanathan, Sritharan, Davis, Peter, Underwood, Timothy, Novelli, Marco R, Rodriguez–Justo, Manuel, Shepherd, Neil, Jansen, Marnix, Wright, Nicholas A, McDonald, Stuart A C
Publicado 2014

Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside of the crypt base stem cell niche

por Davis, Hayley, Irshad, Shazia, Bansal, Mukesh, Rafferty, Hannah, Boitsova, Tatjana, Bardella, Chiara, Jaeger, Emma, Lewis, Annabelle, Freeman-Mills, Luke, Giner, Francesc Castro, Rodenas-Cuadrado, Pedro, Mallappa, Sreelakshmi, Clark, Susan, Thomas, Huw, Jeffery, Rosemary, Poulsom, Richard, Rodriguez-Justo, Manuel, Novelli, Marco, Chetty, Runjan, Silver, Andrew, Sansom, Owen James, Greten, Florian R, Wang, Lai Mun, East, James Edward, Tomlinson, Ian, Leedham, Simon John
Publicado 2014