CCR5 interaction with HIV-1 Env contributes to Env-induced depletion of CD4 T cells in vitro and in vivo

por Tsao, Li-Chung, Guo, Haitao, Jeffrey, Jerry, Hoxie, James A., Su, Lishan
Publicado 2016

The safety, tolerability, and pharmacokinetic profile of GSK2838232, a novel 2nd generation HIV maturation inhibitor, as assessed in healthy subjects

por Johnson, Mark, Jewell, Roxanne C., Peppercorn, Amanda, Gould, Elizabeth, Xu, Jianfeng, Lou, Yu, Davies, Matthew, Baldwin, Sandra, Tenorio, Allan R., Burke, Matthew, Jeffrey, Jerry, Johns, Brian A.
Publicado 2018

Structural Basis for Inhibitor-Induced Aggregation of HIV Integrase

por Gupta, Kushol, Turkki, Vesa, Sherrill-Mix, Scott, Hwang, Young, Eilers, Grant, Taylor, Louis, McDanal, Charlene, Wang, Ping, Temelkoff, David, Nolte, Robert T., Velthuisen, Emile, Jeffrey, Jerry, Van Duyne, Gregory D., Bushman, Frederic D.
Publicado 2016

GSK3640254 Is a Novel HIV-1 Maturation Inhibitor with an Optimized Virology Profile

por Dicker, Ira, Jeffrey, Jerry L., Protack, Tricia, Lin, Zeyu, Cockett, Mark, Chen, Yan, Sit, Sing-Yuen, Gartland, Martin, Meanwell, Nicholas A., Regueiro-Ren, Alicia, Drexler, Dieter, Cantone, Joseph, McAuliffe, Brian, Krystal, Mark
Publicado 2022

Impact of Integrase Sequences from HIV-1 Subtypes A6/A1 on the In Vitro Potency of Cabotegravir or Rilpivirine

por Jeffrey, Jerry L., St. Clair, Marty, Wang, Ping, Wang, Chunfu, Li, Zhufang, Beloor, Jagadish, Talarico, Christine, Fridell, Robert, Krystal, Mark, White, C. Thomas, Griffith, Sandy, D’Amico, Ronald, Smith, Kimberly, Van Eygen, Veerle, Vingerhoets, Johan, Vandermeulen, Kati, Spreen, William, van Lunzen, Jan
Publicado 2022

Phase IIa Proof-of-Concept Evaluation of the Antiviral Efficacy, Safety, Tolerability, and Pharmacokinetics of the Next-Generation Maturation Inhibitor GSK3640254( )

por Spinner, Christoph D, Felizarta, Franco, Rizzardini, Giuliano, Philibert, Patrick, Mitha, Essack, Domingo, Pere, Stephan, Christoph J, DeGrosky, Michelle, Bainbridge, Veronica, Zhan, Joyce, Dumitrescu, Teodora Pene, Jeffrey, Jerry L, Xu, Jianfeng, Halliday, Fiona, Gan, Jianjun, Johnson, Mark, Gartland, Martin, Joshi, Samit R, Lataillade, Max
Publicado 2022

Exploring predictors of HIV-1 virologic failure to long-acting cabotegravir and rilpivirine: a multivariable analysis

por Cutrell, Amy G., Schapiro, Jonathan M., Perno, Carlo F., Kuritzkes, Daniel R., Quercia, Romina, Patel, Parul, Polli, Joseph W., Dorey, David, Wang, Yongwei, Wu, Sterling, Van Eygen, Veerle, Crauwels, Herta, Ford, Susan L., Baker, Mark, Talarico, Christine L., Clair, Marty St, Jeffrey, Jerry, White, C. Thomas, Vanveggel, Simon, Vandermeulen, Kati, Margolis, David A., Aboud, Michael, Spreen, William R., van Lunzen, Jan
Publicado 2021