The IL-15-based superagonist ALT-803 promotes the antigen-independent conversion of memory CD8(+) T cells into innate-like effector cells with antitumor activity

por Wong, Hing C, Jeng, Emily K, Rhode, Peter R
Publicado 2013

Cooperative therapeutic anti-tumor effect of IL-15 agonist ALT-803 and co-targeting soluble NKG2D ligand sMIC

por Basher, Fahmin, Jeng, Emily K., Wong, Hing, Wu, Jennifer
Publicado 2015

The impact of nitrogen oxides on electrochemical carbon dioxide reduction

por Ko, Byung Hee, Hasa, Bjorn, Shin, Haeun, Jeng, Emily, Overa, Sean, Chen, Wilson, Jiao, Feng
Publicado 2020

IL15N72D superagonist/IL15Rα-Fc fusion complex (ALT-803) exhibits anti-metastatic activity in murine breast tumor model

por Kim, Peter S, Kwilas, Anna R, Jeng, Emily K, Wong, Hing C, Schlom, Jeffrey, Hodge, James W
Publicado 2015

IL-15 superagonist/IL-15RαSushi-Fc fusion complex (IL-15SA/IL-15RαSu-Fc; ALT-803) markedly enhances specific subpopulations of NK and memory CD8+ T cells, and mediates potent anti-...

por Kim, Peter S., Kwilas, Anna R., Xu, Wenxin, Alter, Sarah, Jeng, Emily K., Wong, Hing C., Schlom, Jeffrey, Hodge, James W.
Publicado 2016

The IL-15 superagonist ALT-803 enhances anti-CD20 antibody-directed NK cell ADCC and in vivo clearance of B cell lymphomas

por Rosario, Maximillian, Liu, Bai, Kong, Lin, Schneider, Stephanie E, Jeng, Emily K, Rhode, Peter R, Wong, Hing C, Fehniger, Todd A
Publicado 2014

Combinatorial therapy with an IL-15 superagonist (ALT-803) and anti-PD-L1 mAb augment T cell mediated anti-tumor immunity in mice

por Johnson, Christopher B, Riesenberg, Brian, Neitzke, Dan, Jeng, Emily K, Marcus, Warren D, Cole, David, Wong, Hing C, Rubinstein, Mark P
Publicado 2014

Combination therapy of an IL-15 superagonist complex, ALT-803, and a tumor targeting monoclonal antibody promotes direct antitumor activity and protective vaccinal effect in a syng...

por Chen, Xiaoyue, Liu, Bai, Han, Kaiping, Kong, Lin, Noel, Terra, Jeng, Emily K, Alter, Sarah, Rubinstein, Mark, Rhode, Peter R, Wong, Hing C
Publicado 2015

New interleukin-15 superagonist (IL-15SA) significantly enhances graft-versus-tumor activity

por Bailey, Cavan P., Budak-Alpdogan, Tulin, Sauter, Christopher T., Panis, Michelle M., Buyukgoz, Cihangir, Jeng, Emily K., Wong, Hing C., Flomenberg, Neal, Alpdogan, Onder
Publicado 2017

Novel antitumor mechanism-of-action of an IL-2 fusion protein mediated by tumor associated macrophage repolarization and innate-like CD8+ memory T cells

por Xu, Wenxin, Egan, Jack O, Liu, Bai, Chen, Xiaoyue, You, Lijing, Han, Kaiping, Marcus, Warren D, Kong, Lin, Jones, Monica, Jeng, Emily K, Rhode, Peter R, Wong, Hing C
Publicado 2014

Enhancing T cell therapy through TCR signaling-responsive nanoparticle drug delivery

por Tang, Li, Zheng, Yiran, de Melo, Mariane Bandeira, Mabardi, Llian, Castaño, Ana P., Xie, Yu-Qing, Li, Na, Kudchodkar, Sagar B., Wong, Hing C., Jeng, Emily K., Maus, Marcela V., Irvine, Darrell J.
Publicado 2018

A Subset of Latency-Reversing Agents Expose HIV-Infected Resting CD4(+) T-Cells to Recognition by Cytotoxic T-Lymphocytes

por Jones, R. Brad, Mueller, Stefanie, O’Connor, Rachel, Rimpel, Katherine, Sloan, Derek D., Karel, Dan, Wong, Hing C., Jeng, Emily K., Thomas, Allison S., Whitney, James B., Lim, So-Yon, Kovacs, Colin, Benko, Erika, Karandish, Sara, Huang, Szu-Han, Buzon, Maria J., Lichterfeld, Mathias, Irrinki, Alivelu, Murry, Jeffrey P., Tsai, Angela, Yu, Helen, Geleziunas, Romas, Trocha, Alicja, Ostrowski, Mario A., Irvine, Darrell J., Walker, Bruce D.
Publicado 2016

Immunotherapeutic approach to reduce senescent cells and alleviate senescence‐associated secretory phenotype in mice

por Shrestha, Niraj, Chaturvedi, Pallavi, Zhu, Xiaoyun, Dee, Michael J., George, Varghese, Janney, Christopher, Egan, Jack O., Liu, Bai, Foster, Mark, Marsala, Lynne, Wong, Pamela, Cubitt, Celia C., Foltz, Jennifer A., Tran, Jennifer, Schappe, Timothy, Hsiao, Karin, Leclerc, Gilles M., You, Lijing, Echeverri, Christian, Spanoudis, Catherine, Carvalho, Ana, Kanakaraj, Leah, Gilkes, Crystal, Encalada, Nicole, Kong, Lin, Wang, Meng, Fang, Byron, Wang, Zheng, Jiao, Jin‐an, Muniz, Gabriela J., Jeng, Emily K., Valdivieso, Nicole, Li, Liying, Deth, Richard, Berrien‐Elliott, Melissa M., Fehniger, Todd A., Rhode, Peter R., Wong, Hing C.
Publicado 2023