Recent advances and future challenges in gene therapy for hearing loss

por Amariutei, Ana E., Jeng, Jing-Yi, Safieddine, Saaid, Marcotti, Walter
Publicado 2023

TMC2 Modifies Permeation Properties of the Mechanoelectrical Transducer Channel in Early Postnatal Mouse Cochlear Outer Hair Cells

por Corns, Laura F., Jeng, Jing-Yi, Richardson, Guy P., Kros, Corné J., Marcotti, Walter
Publicado 2017

Hair cell maturation is differentially regulated along the tonotopic axis of the mammalian cochlea

por Jeng, Jing‐Yi, Ceriani, Federico, Hendry, Aenea, Johnson, Stuart L., Yen, Piece, Simmons, Dwayne D., Kros, Corné J., Marcotti, Walter
Publicado 2019

Gata3 is required for the functional maturation of inner hair cells and their innervation in the mouse cochlea

por Bardhan, Tanaya, Jeng, Jing‐Yi, Waldmann, Marco, Ceriani, Federico, Johnson, Stuart L., Olt, Jennifer, Rüttiger, Lukas, Marcotti, Walter, Holley, Matthew C.
Publicado 2019

Oncomodulin (OCM) uniquely regulates calcium signaling in neonatal cochlear outer hair cells

por Murtha, Kaitlin E., Yang, Yang, Ceriani, Federico, Jeng, Jing-Yi, Climer, Leslie K., Jones, Forrest, Charles, Jack, Devana, Sai K., Hornak, Aubrey J., Marcotti, Walter, Simmons, Dwayne D.
Publicado 2022

Coordinated calcium signalling in cochlear sensory and non‐sensory cells refines afferent innervation of outer hair cells

por Ceriani, Federico, Hendry, Aenea, Jeng, Jing‐Yi, Johnson, Stuart L, Stephani, Friederike, Olt, Jennifer, Holley, Matthew C, Mammano, Fabio, Engel, Jutta, Kros, Corné J, Simmons, Dwayne D, Marcotti, Walter
Publicado 2019

Loss of Baiap2l2 destabilizes the transducing stereocilia of cochlear hair cells and leads to deafness

por Carlton, Adam J., Halford, Julia, Underhill, Anna, Jeng, Jing‐Yi, Avenarius, Matthew R., Gilbert, Merle L., Ceriani, Federico, Ebisine, Kimimuepigha, Brown, Steve D. M., Bowl, Michael R., Barr‐Gillespie, Peter G., Marcotti, Walter
Publicado 2020

AAV-mediated rescue of Eps8 expression in vivo restores hair-cell function in a mouse model of recessive deafness

por Jeng, Jing-Yi, Carlton, Adam J., Goodyear, Richard J., Chinowsky, Colbie, Ceriani, Federico, Johnson, Stuart L., Sung, Tsung-Chang, Dayn, Yelena, Richardson, Guy P., Bowl, Michael R., Brown, Steve D.M., Manor, Uri, Marcotti, Walter
Publicado 2022

A critical period of prehearing spontaneous Ca(2+) spiking is required for hair‐bundle maintenance in inner hair cells

por Carlton, Adam J, Jeng, Jing‐Yi, Grandi, Fiorella C, De Faveri, Francesca, Ceriani, Federico, De Tomasi, Lara, Underhill, Anna, Johnson, Stuart L, Legan, Kevin P, Kros, Corné J, Richardson, Guy P, Mustapha, Mirna, Marcotti, Walter
Publicado 2023