Structure and function analysis of a type III preQ(1)-I riboswitch from Escherichia coli reveals direct metabolite sensing by the Shine-Dalgarno sequence

por Schroeder, Griffin M., Kiliushik, Daniil, Jenkins, Jermaine L., Wedekind, Joseph E.
Publicado 2023

U2AF(65) adapts to diverse pre-mRNA splice sites through conformational selection of specific and promiscuous RNA recognition motifs

por Jenkins, Jermaine L., Agrawal, Anant A., Gupta, Ankit, Green, Michael R., Kielkopf, Clara L.
Publicado 2013

Co-crystal structures of HIV TAR RNA bound to lab-evolved proteins show key roles for arginine relevant to the design of cyclic peptide TAR inhibitors

por Chavali, Sai Shashank, Mali, Sachitanand M., Jenkins, Jermaine L., Fasan, Rudi, Wedekind, Joseph E.
Publicado 2021

Affinity and Structural Analysis of the U1A RNA Recognition Motif with Engineered Methionines to Improve Experimental Phasing

por Srivastava, Yoshita, Bonn-Breach, Rachel, Chavali, Sai Shashank, Lippa, Geoffrey M., Jenkins, Jermaine L., Wedekind, Joseph E.
Publicado 2021

A small RNA that cooperatively senses two stacked metabolites in one pocket for gene control

por Schroeder, Griffin M., Cavender, Chapin E., Blau, Maya E., Jenkins, Jermaine L., Mathews, David H., Wedekind, Joseph E.
Publicado 2022

An extended U2AF(65)–RNA-binding domain recognizes the 3′ splice site signal

por Agrawal, Anant A., Salsi, Enea, Chatrikhi, Rakesh, Henderson, Steven, Jenkins, Jermaine L., Green, Michael R., Ermolenko, Dmitri N., Kielkopf, Clara L.
Publicado 2016

Cus2 enforces the first ATP-dependent step of splicing by binding to yeast SF3b1 through a UHM–ULM interaction

por Talkish, Jason, Igel, Haller, Hunter, Oarteze, Horner, Steven W., Jeffery, Nazish N., Leach, Justin R., Jenkins, Jermaine L., Kielkopf, Clara L., Ares, Manuel
Publicado 2019

Analysis of a preQ(1)-I riboswitch in effector-free and bound states reveals a metabolite-programmed nucleobase-stacking spine that controls gene regulation

por Schroeder, Griffin M, Dutta, Debapratim, Cavender, Chapin E, Jenkins, Jermaine L, Pritchett, Elizabeth M, Baker, Cameron D, Ashton, John M, Mathews, David H, Wedekind, Joseph E
Publicado 2020

Pre-mRNA splicing factor U2AF2 recognizes distinct conformations of nucleotide variants at the center of the pre-mRNA splice site signal

por Glasser, Eliezra, Maji, Debanjana, Biancon, Giulia, Puthenpeedikakkal, Anees Mohammed Keedakkatt, Cavender, Chapin E, Tebaldi, Toma, Jenkins, Jermaine L, Mathews, David H, Halene, Stephanie, Kielkopf, Clara L
Publicado 2022

A UHM–ULM interface with unusual structural features contributes to U2AF2 and SF3B1 association for pre-mRNA splicing

por Galardi, Justin W., Bela, Victoria N., Jeffery, Nazish, He, Xueyang, Glasser, Eliezra, Loerch, Sarah, Jenkins, Jermaine L., Pulvino, Mary J., Boutz, Paul L., Kielkopf, Clara L.
Publicado 2022

A riboswitch separated from its ribosome-binding site still regulates translation

por Schroeder, Griffin M, Akinyemi, Olayinka, Malik, Jeffrey, Focht, Caroline M, Pritchett, Elizabeth M, Baker, Cameron D, McSally, James P, Jenkins, Jermaine L, Mathews, David H, Wedekind, Joseph E
Publicado 2023