Trans-synaptic spreading of alpha-synuclein pathology through sensory afferents leads to sensory nerve degeneration and neuropathic pain

por Ferreira, Nelson, Gonçalves, Nádia Pereira, Jan, Asad, Jensen, Nanna Møller, van der Laan, Amelia, Mohseni, Simin, Vægter, Christian Bjerggaard, Jensen, Poul Henning
Publicado 2021

Polo-like kinase 2 inhibition reduces serine-129 phosphorylation of physiological nuclear alpha-synuclein but not of the aggregated alpha-synuclein

por Elfarrash, Sara, Jensen, Nanna Møller, Ferreira, Nelson, Schmidt, Sissel Ida, Gregersen, Emil, Vestergaard, Marie Vibeke, Nabavi, Sadegh, Meyer, Morten, Jensen, Poul Henning
Publicado 2021

Protein kinase R dependent phosphorylation of α-synuclein regulates its membrane binding and aggregation

por Reimer, Lasse, Gram, Hjalte, Jensen, Nanna Møller, Betzer, Cristine, Yang, Li, Jin, Lorrain, Shi, Min, Boudeffa, Driss, Fusco, Giuliana, De Simone, Alfonso, Kirik, Deniz, Lashuel, Hilal A, Zhang, Jing, Jensen, Poul Henning
Publicado 2022

Organotypic slice culture model demonstrates inter-neuronal spreading of alpha-synuclein aggregates

por Elfarrash, Sara, Jensen, Nanna Møller, Ferreira, Nelson, Betzer, Cristine, Thevathasan, Jervis Vermal, Diekmann, Robin, Adel, Mohamed, Omar, Nisreen Mansour, Boraie, Mohamed Z., Gad, Sabry, Ries, Jonas, Kirik, Deniz, Nabavi, Sadegh, Jensen, Poul Henning
Publicado 2019

α-Synuclein phosphorylation at serine 129 occurs after initial protein deposition and inhibits seeded fibril formation and toxicity

por Ghanem, Simona S., Majbour, Nour K., Vaikath, Nishant N., Ardah, Mustafa T., Erskine, Daniel, Jensen, Nanna Møller, Fayyad, Muneera, Sudhakaran, Indulekha P., Vasili, Eftychia, Melachroinou, Katerina, Abdi, Ilham Y., Poggiolini, Ilaria, Santos, Patricia, Dorn, Anton, Carloni, Paolo, Vekrellis, Kostas, Attems, Johannes, McKeith, Ian, Outeiro, Tiago F., Jensen, Poul Henning, El-Agnaf, Omar M. A.
Publicado 2022