Reduced Cytosolic Calcium as an Early Decisive Cellular State in Parkinson’s Disease and Synucleinopathies

por Betzer, Cristine, Jensen, Poul Henning
Publicado 2018

Organotypic hippocampal slices, an emerging tool to model synucleinopathies

por Elfarrash, Sara, Jensen, Poul Henning
Publicado 2020

Endoplasmic Reticulum-Based Calcium Dysfunctions in Synucleinopathies

por Kovacs, Gergo, Reimer, Lasse, Jensen, Poul Henning
Publicado 2021

Sarkosyl differentially solubilizes patient-derived alpha-synuclein fibril strains

por Gram, Hjalte, Theologidis, Vasileios, Boesen, Thomas, Jensen, Poul Henning
Publicado 2023

Stabilization of α-synuclein oligomers using formaldehyde

por Ruesink, Harm, Reimer, Lasse, Gregersen, Emil, Moeller, Arne, Betzer, Cristine, Jensen, Poul Henning
Publicado 2019

The Prion-Like Spreading of Alpha-Synuclein in Parkinson’s Disease: Update on Models and Hypotheses

por Jan, Asad, Gonçalves, Nádia Pereira, Vaegter, Christian Bjerggaard, Jensen, Poul Henning, Ferreira, Nelson
Publicado 2021

Identification of Synaptosomal Proteins Binding to Monomeric and Oligomeric α-Synuclein

por Betzer, Cristine, Movius, A. James, Shi, Min, Gai, Wei-Ping, Zhang, Jing, Jensen, Poul Henning
Publicado 2015

ELISA method to detect α-synuclein oligomers in cell and animal models

por Lassen, Louise Berkhoudt, Gregersen, Emil, Isager, Anne Kathrine, Betzer, Cristine, Kofoed, Rikke Hahn, Jensen, Poul Henning
Publicado 2018

Recombinant adeno-associated virus mediated gene delivery in the extracranial nervous system of adult mice by direct nerve immersion

por Richner, Mette, Gonçalves, Nádia Pereira, Jensen, Poul Henning, Nyengaard, Jens Randel, Vægter, Christian Bjerggaard, Jan, Asad
Publicado 2022

Long-Term Exposure to PFE-360 in the AAV-α-Synuclein Rat Model: Findings and Implications

por Andersen, Michael Aagaard, Sotty, Florence, Jensen, Poul Henning, Badolo, Lassina, Jeggo, Ross, Smith, Garrick Paul, Christensen, Kenneth Vielsted
Publicado 2019

Alpha-synuclein activates the classical complement pathway and mediates complement-dependent cell toxicity

por Gregersen, Emil, Betzer, Cristine, Kim, Woojin S., Kovacs, Gergo, Reimer, Lasse, Halliday, Glenda M., Thiel, Steffen, Jensen, Poul Henning
Publicado 2021

CD4 T cells react to local increase of α-synuclein in a pathology-associated variant-dependent manner and modify brain microglia in absence of brain pathology

por Olesen, Mads N., Christiansen, Josefine R., Petersen, Steen Vang, Jensen, Poul Henning, Paslawski, Wojciech, Romero-Ramos, Marina, Sanchez-Guajardo, Vanesa
Publicado 2018

PKR kinase directly regulates tau expression and Alzheimer's disease‐related tau phosphorylation

por Reimer, Lasse, Betzer, Cristine, Kofoed, Rikke Hahn, Volbracht, Christiane, Fog, Karina, Kurhade, Chaitanya, Nilsson, Emma, Överby, Anna K., Jensen, Poul Henning
Publicado 2020

Prolyl oligopeptidase inhibition reduces alpha‐synuclein aggregation in a cellular model of multiple system atrophy

por Cui, Hengjing, Kilpeläinen, Tommi, Zouzoula, Lydia, Auno, Samuli, Trontti, Kalevi, Kurvonen, Sampo, Norrbacka, Susanna, Hovatta, Iiris, Jensen, Poul Henning, Myöhänen, Timo T.
Publicado 2021

Mutation of Tyrosine Sites in the Human Alpha-Synuclein Gene Induces Neurotoxicity in Transgenic Mice with Soluble Alpha-Synuclein Oligomer Formation

por Lassen, Louise Berkhoudt, Thomsen, Maj Schneider, Basso, Elisa, Füchtbauer, Ernst-Martin, Füchtbauer, Annette, Outeiro, Tiago Fleming, Jensen, Poul Henning, Moos, Torben
Publicado 2022

Trans-synaptic spreading of alpha-synuclein pathology through sensory afferents leads to sensory nerve degeneration and neuropathic pain

por Ferreira, Nelson, Gonçalves, Nádia Pereira, Jan, Asad, Jensen, Nanna Møller, van der Laan, Amelia, Mohseni, Simin, Vægter, Christian Bjerggaard, Jensen, Poul Henning
Publicado 2021

Polo-like kinase 2 inhibition reduces serine-129 phosphorylation of physiological nuclear alpha-synuclein but not of the aggregated alpha-synuclein

por Elfarrash, Sara, Jensen, Nanna Møller, Ferreira, Nelson, Schmidt, Sissel Ida, Gregersen, Emil, Vestergaard, Marie Vibeke, Nabavi, Sadegh, Meyer, Morten, Jensen, Poul Henning
Publicado 2021

Polarized α-synuclein trafficking and transcytosis across brain endothelial cells via Rab7-decorated carriers

por Alam, Parvez, Holst, Mikkel R., Lauritsen, Line, Nielsen, Janni, Nielsen, Simone S. E., Jensen, Poul Henning, Brewer, Jonathan R., Otzen, Daniel E., Nielsen, Morten S.
Publicado 2022

Alpha-Synuclein Strain Variability in Body-First and Brain-First Synucleinopathies

por Just, Mie Kristine, Gram, Hjalte, Theologidis, Vasileios, Jensen, Poul Henning, Nilsson, K. Peter R., Lindgren, Mikael, Knudsen, Karoline, Borghammer, Per, Van Den Berge, Nathalie
Publicado 2022

Structural and functional characterization of two alpha-synuclein strains

por Bousset, Luc, Pieri, Laura, Ruiz-Arlandis, Gemma, Gath, Julia, Jensen, Poul Henning, Habenstein, Birgit, Madiona, Karine, Olieric, Vincent, Böckmann, Anja, Meier, Beat H., Melki, Ronald
Publicado 2013