BRCA2: One Small Step for DNA Repair, One Giant Protein Purified

por Jensen, Ryan B.
Publicado 2013

Preserving genome integrity in human cells via DNA double-strand break repair

por Jensen, Ryan B., Rothenberg, Eli
Publicado 2020

Imprecise Medicine: BRCA2 Variants of Uncertain Significance (VUS), the Challenges and Benefits to Integrate a Functional Assay Workflow with Clinical Decision Rules

por Jimenez-Sainz, Judit, Jensen, Ryan B.
Publicado 2021

Polymerase θ Coordinates Multiple Intrinsic Enzymatic Activities during DNA Repair

por Zahn, Karl E., Jensen, Ryan B.
Publicado 2021

Purified human BRCA2 stimulates RAD51-mediated recombination

por Jensen, Ryan B., Carreira, Aura, Kowalczykowski, Stephen C.
Publicado 2010

DNA fiber combing protocol using in-house reagents and coverslips to analyze replication fork dynamics in mammalian cells

por Moore, Gemma, Jimenez Sainz, Judit, Jensen, Ryan B.
Publicado 2022

A cell-penetrating antibody inhibits human RAD51 via direct binding

por Turchick, Audrey, Hegan, Denise C., Jensen, Ryan B., Glazer, Peter M.
Publicado 2017

Distinct binding of BRCA2 BRC repeats to RAD51 generates differential DNA damage sensitivity

por Chatterjee, Gouri, Jimenez-Sainz, Judit, Presti, Thomas, Nguyen, Tiffany, Jensen, Ryan B.
Publicado 2016

The Post-Synaptic Function of Brca2

por Wang, Charles X., Jimenez-Sainz, Judit, Jensen, Ryan B., Mazin, Alexander V.
Publicado 2019

Loss of ATRX confers DNA repair defects and PARP inhibitor sensitivity

por Garbarino, Jennifer, Eckroate, Jillian, Sundaram, Ranjini K., Jensen, Ryan B., Bindra, Ranjit S.
Publicado 2021

The Pathogenic R3052W BRCA2 Variant Disrupts Homology-Directed Repair by Failing to Localize to the Nucleus

por Jimenez-Sainz, Judit, Krysztofiak, Adam, Garbarino, Jennifer, Rogers, Faye, Jensen, Ryan B.
Publicado 2022

BRCA2 chaperones RAD51 to single molecules of RPA-coated ssDNA

por Bell, Jason C., Dombrowski, Christopher C., Plank, Jody L., Jensen, Ryan B., Kowalczykowski, Stephen C.
Publicado 2023

The Tumor-Associated Variant RAD51 G151D Induces a Hyper-Recombination Phenotype

por Marsden, Carolyn G., Jensen, Ryan B., Zagelbaum, Jennifer, Rothenberg, Eli, Morrical, Scott W., Wallace, Susan S., Sweasy, Joann B.
Publicado 2016

BRCA2 BRC missense variants disrupt RAD51-dependent DNA repair

por Jimenez-Sainz, Judit, Mathew, Joshua, Moore, Gemma, Lahiri, Sudipta, Garbarino, Jennifer, Eder, Joseph P, Rothenberg, Eli, Jensen, Ryan B
Publicado 2022