Small molecule H89 renders the phosphorylation of S6K1 and AKT resistant to mTOR inhibitors

por Melick, Chase H., Jewell, Jenna L.
Publicado 2020

Regulation of mTORC1 by Upstream Stimuli

por Melick, Chase H., Jewell, Jenna L.
Publicado 2020

Amino acid and small GTPase regulation of mTORC1

por Nguyen, Thu P., Frank, Anderson R., Jewell, Jenna L.
Publicado 2017

Regulation of mTORC1 by the Rag GTPases

por Lama-Sherpa, Tshering D., Jeong, Mi-Hyeon, Jewell, Jenna L.
Publicado 2023

Inhibition of phosphodiesterase 4D suppresses mTORC1 signaling and pancreatic cancer growth

por Jeong, Mi-Hyeon, Urquhart, Greg, Lewis, Cheryl, Chi, Zhikai, Jewell, Jenna L.
Publicado 2023

G-Protein Coupled Receptor Signaling and Mammalian Target of Rapamycin Complex 1 Regulation

por Melick, Chase H., Lama-Sherpa, Tshering D., Curukovic, Adna, Jewell, Jenna L.
Publicado 2022

Munc18c phosphorylation by the insulin receptor links cell signaling directly to SNARE exocytosis

por Jewell, Jenna L., Oh, Eunjin, Ramalingam, Latha, Kalwat, Michael A., Tagliabracci, Vincent S., Tackett, Lixuan, Elmendorf, Jeffrey S., Thurmond, Debbie C.
Publicado 2011

NLK phosphorylates Raptor to mediate stress-induced mTORC1 inhibition

por Yuan, Hai-Xin, Wang, Zhen, Yu, Fa-Xing, Li, Fulong, Russell, Ryan C., Jewell, Jenna L., Guan, Kun-Liang
Publicado 2015

Differential regulation of mTORC1 by leucine and glutamine

por Jewell, Jenna L., Kim, Young Chul, Russell, Ryan C., Yu, Fa-Xing, Park, Hyun Woo, Plouffe, Steven W., Tagliabracci, Vincent S., Guan, Kun-Liang
Publicado 2015

Rag GTPases are cardioprotective by regulating lysosomal function

por Kim, Young Chul, Park, Hyun Woo, Sciarretta, Sebastiano, Mo, Jung-Soon, Jewell, Jenna L., Russell, Ryan C., Wu, Xiaohui, Sadoshima, Junichi, Guan, Kun-Liang
Publicado 2014

ArfGAP1 inhibits mTORC1 lysosomal localization and activation

por Meng, Delong, Yang, Qianmei, Melick, Chase H, Park, Brenden C, Hsieh, Ting‐Sung, Curukovic, Adna, Jeong, Mi‐Hyeon, Zhang, Junmei, James, Nicholas G, Jewell, Jenna L
Publicado 2021

AKAP13 couples GPCR signaling to mTORC1 inhibition

por Zhang, Shihai, Wang, Huanyu, Melick, Chase H., Jeong, Mi-Hyeon, Curukovic, Adna, Tiwary, Shweta, Lama-Sherpa, Tshering D., Meng, Delong, Servage, Kelly A., James, Nicholas G., Jewell, Jenna L.
Publicado 2021

GPCR signaling inhibits mTORC1 via PKA phosphorylation of Raptor

por Jewell, Jenna L, Fu, Vivian, Hong, Audrey W, Yu, Fa-Xing, Meng, Delong, Melick, Chase H, Wang, Huanyu, Lam, Wai-Ling Macrina, Yuan, Hai-Xin, Taylor, Susan S, Guan, Kun-Liang
Publicado 2019

SNAT7 regulates mTORC1 via macropinocytosis

por Meng, Delong, Yang, Qianmei, Jeong, Mi-Hyeon, Curukovic, Adna, Tiwary, Shweta, Melick, Chase H., Lama-Sherpa, Tshering D., Wang, Huanyu, Huerta-Rosario, Mariela, Urquhart, Greg, Zacharias, Lauren G., Lewis, Cheryl, DeBerardinis, Ralph J., Jewell, Jenna L.
Publicado 2022