Canine osteosarcoma in comparative oncology: Molecular mechanisms through to treatment discovery

por Simpson, Siobhan, Rizvanov, Albert A., Jeyapalan, Jennie N., de Brot, Simone, Rutland, Catrin S.
Publicado 2022

Evolving DNA repair synthetic lethality targets in cancer

por Kulkarni, Sanat, Brownlie, Juliette, Jeyapalan, Jennie N., Mongan, Nigel P., Rakha, Emad A., Madhusudan, Srinivasan
Publicado 2022

The roles of WRN and BLM RecQ helicases in the Alternative Lengthening of Telomeres

por Mendez-Bermudez, Aaron, Hidalgo-Bravo, Alberto, Cotton, Victoria E., Gravani, Athanasia, Jeyapalan, Jennie N., Royle, Nicola J.
Publicado 2012

Impact of COVID‐19 on student attainment and pedagogical needs when undertaking independent scientific research

por Jeyapalan, Jennie N., James, Victoria., Gardner, David S., Lothion‐Roy, Jennifer H., Mongan, Nigel P., Rutland, Catrin Sian
Publicado 2022

Towards Personalized Management of Ovarian Cancer

por Algethami, Mashael, Kulkarni, Sanat, Sadiq, Maaz T, Tang, Hiu K C, Brownlie, Juliette, Jeyapalan, Jennie N, Mongan, Nigel P, Rakha, Emad A, Madhusudan, Srinivasan
Publicado 2022

Genome-wide methylation analysis identifies genes silenced in non-seminoma cell lines

por Noor, Dzul Azri Mohamed, Jeyapalan, Jennie N, Alhazmi, Safiah, Carr, Matthew, Squibb, Benjamin, Wallace, Claire, Tan, Christopher, Cusack, Martin, Hughes, Jaime, Reader, Tom, Shipley, Janet, Sheer, Denise, Scotting, Paul J
Publicado 2016

Unravelling the clinicopathological and functional significance of replication protein A (RPA) heterotrimeric complex in breast cancers

por Algethami, Mashael, Toss, Michael S., Woodcock, Corinne L., Jaipal, Chandar, Brownlie, Juliette, Shoqafi, Ahmed, Alblihy, Adel, Mesquita, Katia A., Green, Andrew R., Mongan, Nigel P., Jeyapalan, Jennie N., Rakha, Emad A., Madhusudan, Srinivasan
Publicado 2023

Untangling the clinicopathological significance of MRE11-RAD50-NBS1 complex in sporadic breast cancers

por Alblihy, Adel, Shoqafi, Ahmed, Toss, Michael S., Algethami, Mashael, Harris, Anna E., Jeyapalan, Jennie N., Abdel-Fatah, Tarek, Servante, Juliette, Chan, Stephen Y. T., Green, Andrew, Mongan, Nigel P., Rakha, Emad A., Madhusudan, Srinivasan
Publicado 2021

Targeting Mre11 overcomes platinum resistance and induces synthetic lethality in XRCC1 deficient epithelial ovarian cancers

por Alblihy, Adel, Ali, Reem, Algethami, Mashael, Shoqafi, Ahmed, Toss, Michael S., Brownlie, Juliette, Tatum, Natalie J., Hickson, Ian, Moran, Paloma Ordonez, Grabowska, Anna, Jeyapalan, Jennie N., Mongan, Nigel P., Rakha, Emad A., Madhusudan, Srinivasan
Publicado 2022

Molecular analysis of pediatric brain tumors identifies microRNAs in pilocytic astrocytomas that target the MAPK and NF-κB pathways

por Jones, Tania A., Jeyapalan, Jennie N., Forshew, Tim, Tatevossian, Ruth G., Lawson, Andrew R. J., Patel, Sheena N., Doctor, Gabriel T., Mumin, Muhammad A., Picker, Simon R., Phipps, Kim P., Michalski, Antony, Jacques, Thomas S., Sheer, Denise
Publicado 2015

Immunohistochemical Characterisation of GLUT1, MMP3 and NRF2 in Osteosarcoma

por Rutland, Catrin S., Cockcroft, James M., Lothion-Roy, Jennifer, Harris, Anna E., Jeyapalan, Jennie N., Simpson, Siobhan, Alibhai, Aziza, Bailey, Clara, Ballard-Reisch, Alyssa C., Rizvanov, Albert A., Dunning, Mark D., de Brot, Simone, Mongan, Nigel P.
Publicado 2021

Molecular Characterisation of Canine Osteosarcoma in High Risk Breeds

por Simpson, Siobhan, Dunning, Mark, de Brot, Simone, Alibhai, Aziza, Bailey, Clara, Woodcock, Corinne L., Mestas, Madeline, Akhtar, Shareen, Jeyapalan, Jennie N., Lothion-Roy, Jennifer, Emes, Richard D., Allegrucci, Cinzia, Rizvanov, Albert A., Mongan, Nigel P., Rutland, Catrin S.
Publicado 2020

Selective Killing of BRCA2-Deficient Ovarian Cancer Cells via MRE11 Blockade

por Alblihy, Adel, Ali, Reem, Algethami, Mashael, Ritchie, Alison A., Shoqafi, Ahmed, Alqahtani, Shatha, Mesquita, Katia A., Toss, Michael S., Ordóñez-Morán, Paloma, Jeyapalan, Jennie N., Dekker, Lodewijk, Salerno, Martina, Hartsuiker, Edgar, Grabowska, Anna M., Rakha, Emad A., Mongan, Nigel P., Madhusudan, Srinivasan
Publicado 2023

Comparative pathology of dog and human prostate cancer

por Ryman‐Tubb, Toby, Lothion‐Roy, Jennifer H., Metzler, Veronika M., Harris, Anna E., Robinson, Brian D., Rizvanov, Albert A., Jeyapalan, Jennie N., James, Victoria H., England, Gary, Rutland, Catrin S., Persson, Jenny L., Kenner, Lukas, Rubin, Mark A., Mongan, Nigel P., de Brot, Simone
Publicado 2021

DNA methylation analysis of paediatric low-grade astrocytomas identifies a tumour-specific hypomethylation signature in pilocytic astrocytomas

por Jeyapalan, Jennie N., Doctor, Gabriel T., Jones, Tania A., Alberman, Samuel N., Tep, Alexander, Haria, Chirag M., Schwalbe, Edward C., Morley, Isabel C. F., Hill, Alfred A., LeCain, Magdalena, Ottaviani, Diego, Clifford, Steven C., Qaddoumi, Ibrahim, Tatevossian, Ruth G., Ellison, David W., Sheer, Denise
Publicado 2016

Expression of NAD(P)H quinone dehydrogenase 1 (NQO1) is increased in the endometrium of women with endometrial cancer and women with polycystic ovary syndrome

por Atiomo, William, Shafiee, Mohamad Nasir, Chapman, Caroline, Metzler, Veronika M., Abouzeid, Jad, Latif, Ayşe, Chadwick, Amy, Kitson, Sarah, Sivalingam, Vanitha N., Stratford, Ian J., Rutland, Catrin S., Persson, Jenny L., Ødum, Niels, Fuentes‐Utrilla, Pablo, Jeyapalan, Jennie N., Heery, David M., Crosbie, Emma J., Mongan, Nigel P.
Publicado 2017

The KDM5B and KDM1A lysine demethylases cooperate in regulating androgen receptor expression and signalling in prostate cancer

por Metzler, Veronika M., de Brot, Simone, Haigh, Daisy B., Woodcock, Corinne L., Lothion-Roy, Jennifer, Harris, Anna E., Nilsson, Emeli M., Ntekim, Atara, Persson, Jenny L., Robinson, Brian D., Khani, Francesca, Laursen, Kristian B., Gudas, Lorraine J., Toss, Michael S., Madhusudan, Srinivasan, Rakha, Emad, Heery, David M., Rutland, Catrin S., Mongan, Nigel P., Jeyapalan, Jennie N.
Publicado 2023

The METTL3 RNA Methyltransferase Regulates Transcriptional Networks in Prostate Cancer

por Haigh, Daisy B., Woodcock, Corinne L., Lothion-Roy, Jennifer, Harris, Anna E., Metzler, Veronika M., Persson, Jenny L., Robinson, Brian D., Khani, Francesca, Alsaleem, Mansour, Ntekim, Atara, Madhusudan, Srinivasan, Davis, Melissa B., Laursen, Kristian B., Gudas, Lorraine J., Rutland, Catrin S., Toss, Michael S., Archer, Nathan, Bodi, Zsuzsanna, Rakha, Emad A., Fray, Rupert G., Jeyapalan, Jennie N., Mongan, Nigel P.
Publicado 2022

Clinical and molecular significance of the RNA m(6)A methyltransferase complex in prostate cancer

por Lothion-Roy, Jennifer, Haigh, Daisy B., Harris, Anna E., Metzler, Veronika M., Alsaleem, Mansour, Toss, Michael S., Kariri, Yousif, Ntekim, Atara, Robinson, Brian D., Khani, Francesca, Gudas, Lorraine J., Allegrucci, Cinzia, James, Victoria H., Madhusudan, Srinivasan, Mather, Melissa, Emes, Richard D., Archer, Nathan, Fray, Rupert G., Rakha, Emad, Jeyapalan, Jennie N., Rutland, Catrin S., Mongan, Nigel P., Woodcock, Corinne L.
Publicado 2023

Exploring anti-androgen therapies in hormone dependent prostate cancer and new therapeutic routes for castration resistant prostate cancer

por Harris, Anna E., Metzler, Veronika M., Lothion-Roy, Jennifer, Varun, Dhruvika, Woodcock, Corinne L., Haigh, Daisy B., Endeley, Chantelle, Haque, Maria, Toss, Michael S., Alsaleem, Mansour, Persson, Jenny L., Gudas, Lorraine J., Rakha, Emad, Robinson, Brian D., Khani, Francesca, Martin, Laura M., Moyer, Jenna E., Brownlie, Juliette, Madhusudan, Srinivasan, Allegrucci, Cinzia, James, Victoria H., Rutland, Catrin S., Fray, Rupert G., Ntekim, Atara, de Brot, Simone, Mongan, Nigel P., Jeyapalan, Jennie N.
Publicado 2022