A Randomized, Double-Blind, Placebo- and Active-Controlled, Escalating Single-Dose Study to Evaluate the Safety, Tolerability, Pharmacokinetic, and Pharmacodynamic Profiles of Subc...

por Jeon, Yoomin, Lee, Nora, Baek, Seungjae, Choi, JaeDuk, Jhee, Stanford, Lee, Howard
Publicado 2022

Evaluation of the single-dose pharmacokinetics and pharmacodynamics of apixaban in healthy Japanese and Caucasian subjects

por Frost, Charles, Shenker, Andrew, Jhee, Stanford, Yu, Zhigang, Wang, Jessie, Bragat, Alexander, Pursley, Janice, LaCreta, Frank
Publicado 2018

The effect of LCZ696 (sacubitril/valsartan) on amyloid‐β concentrations in cerebrospinal fluid in healthy subjects

por Langenickel, Thomas H., Tsubouchi, Chiaki, Ayalasomayajula, Surya, Pal, Parasar, Valentin, Marie‐Anne, Hinder, Markus, Jhee, Stanford, Gevorkyan, Hakop, Rajman, Iris
Publicado 2016

A first-in-human study to investigate the safety, tolerability, pharmacokinetics, and pharmacodynamics of KM-819 (FAS-associated factor 1 inhibitor), a drug for Parkinson’s disease...

por Shin, Wonsuk, Lim, Kyoung Soo, Kim, Min-Kyoung, Kim, Hyun Sook, Hong, Jihwa, Jhee, Stanford, Kim, Joseph, Yoo, Sungeun, Chung, Yeon-Tae, Lee, Jae Moon, Cho, Doo-Yeoun
Publicado 2019

Robust Pharmacodynamic Effect of LY3202626, a Central Nervous System Penetrant, Low Dose BACE1 Inhibitor, in Humans and Nonclinical Species

por Willis, Brian A., Lowe, Stephen L., Monk, Scott A., Cocke, Patrick J., Aluise, Christopher D., Boggs, Leonard N., Borders, Anthony R., Brier, Richard A., Dean, Robert A., Green, Steven J., James, Douglas E., Jhee, Stanford S., Lin, Qun, Lo, Albert C., May, Patrick C., Watson, Brian M., Winneroski, Leonard L., Yang, Zhixiang, Zimmer, Jennifer A., McKinzie, David L., Mergott, Dustin J.
Publicado 2022