Disruption of sirtuin 7 in zebrafish facilitates hypoxia tolerance

por Liao, Qian, Zhu, Chunchun, Sun, Xueyi, Wang, Zixuan, Chen, Xiaoyun, Deng, Hongyan, Tang, Jinhua, Jia, Shuke, Liu, Wen, Xiao, Wuhan, Liu, Xing
Publicado 2023

Methyltransferase SMYD3 impairs hypoxia tolerance by augmenting hypoxia signaling independent of its enzymatic activity

por Wang, Zixuan, Chen, Xiaoyun, Fan, Sijia, Zhu, Chunchun, Deng, Hongyan, Tang, Jinhua, Sun, Xueyi, Jia, Shuke, Liao, Qian, Xiao, Wuhan, Liu, Xing
Publicado 2022

EGLN1 prolyl hydroxylation of hypoxia-induced transcription factor HIF1α is repressed by SET7-catalyzed lysine methylation

por Tang, Jinhua, Deng, Hongyan, Wang, Zixuan, Zha, Huangyuan, Liao, Qian, Zhu, Chunchun, Chen, Xiaoyun, Sun, Xueyi, Jia, Shuke, Ouyang, Gang, Liu, Xing, Xiao, Wuhan
Publicado 2022

OTUB1 augments hypoxia signaling via its non-canonical ubiquitination inhibition of HIF-1α during hypoxia adaptation

por Liu, Xing, Deng, Hongyan, Tang, Jinhua, Wang, Zixuan, Zhu, Chunchun, Cai, Xiaolian, Rong, Fangjing, Chen, Xiaoyun, Sun, Xueyi, Jia, Shuke, Ouyang, Gang, Li, Wenhua, Xiao, Wuhan
Publicado 2022

SET7 methylates the deubiquitinase OTUB1 at Lys (122) to impair its binding to E2 enzyme UBC13 and relieve its suppressive role on ferroptosis

por Deng, Hongyan, Jia, Shuke, Tang, Jinhua, Rong, Fangjing, Xu, Chenxi, Chen, Xiaoyun, Wang, Zixuan, Zhu, Chunchun, Sun, Xueyi, Liao, Qian, Liu, Wen, Li, Wenhua, Xiao, Wuhan, Liu, Xing
Publicado 2023