OBATOCLAX and ABT-737 Induce ER Stress Responses in Human Melanoma Cells that Limit Induction of Apoptosis

por Wroblewski, David, Jiang, Chen Chen, Croft, Amanda, Farrelly, Margaret L., Zhang, Xu Dong, Hersey, Peter
Publicado 2013

Connecting endoplasmic reticulum stress to autophagy through IRE1/JNK/beclin-1 in breast cancer cells

por Cheng, Xiu, Liu, Hao, Jiang, Chen-Chen, Fang, Lin, Chen, Chao, Zhang, Xu-Dong, Jiang, Zhi-Wen
Publicado 2021

Signalling pathways in autism spectrum disorder: mechanisms and therapeutic implications

por Jiang, Chen-Chen, Lin, Li-Shan, Long, Sen, Ke, Xiao-Yan, Fukunaga, Kohji, Lu, Ying-Mei, Han, Feng
Publicado 2022

Suppression of endoplasmic reticulum stress-induced invasion and migration of breast cancer cells through the downregulation of heparanase

por Li, Yang, Liu, Hao, Huang, Ying Ying, Pu, Long Jian, Zhang, Xu Dong, Jiang, Chen Chen, Jiang, Zhi Wen
Publicado 2021

Expression of NGF/proNGF and Their Receptors TrkA, p75(NTR) and Sortilin in Melanoma

por Marsland, Mark, Dowdell, Amiee, Jiang, Chen Chen, Wilmott, James S., Scolyer, Richard A., Zhang, Xu Dong, Hondermarck, Hubert, Faulkner, Sam
Publicado 2022

Targeting XBP1 mRNA splicing sensitizes glioblastoma to chemotherapy

por Dowdell, Amiee, Marsland, Mark, Faulkner, Sam, Gedye, Craig, Lynam, James, Griffin, Cassandra P., Marsland, Joanne, Jiang, Chen Chen, Hondermarck, Hubert
Publicado 2023

The Membrane Protein Sortilin Is a Potential Biomarker and Target for Glioblastoma

por Marsland, Mark, Dowdell, Amiee, Faulkner, Sam, Gedye, Craig, Lynam, James, Griffin, Cassandra P., Marsland, Joanne, Jiang, Chen Chen, Hondermarck, Hubert
Publicado 2023

Shikonin induces programmed death of fibroblast synovial cells in rheumatoid arthritis by inhibiting energy pathways

por Li, Jiahui, Pang, Jinglong, Liu, Zhe, Ge, XianMing, Zhen, Yanan, Jiang, Chen Chen, Liu, Yaming, Huo, Qiang, Sun, Yiming, Liu, Hao
Publicado 2021

Sortilin is associated with breast cancer aggressiveness and contributes to tumor cell adhesion and invasion

por Roselli, Séverine, Pundavela, Jay, Demont, Yohann, Faulkner, Sam, Keene, Sheridan, Attia, John, Jiang, Chen Chen, Zhang, Xu Dong, Walker, Marjorie M., Hondermarck, Hubert
Publicado 2015

2-Deoxy-D-glucose enhances TRAIL-induced apoptosis in human melanoma cells through XBP-1-mediated up-regulation of TRAIL-R2

por Liu, Hao, Jiang, Chen Chen, Lavis, Christopher J, Croft, Amanda, Dong, Li, Tseng, Hsin-Yi, Yang, Fan, Tay, Kwang Hong, Hersey, Peter, Zhang, Xu Dong
Publicado 2009

Schwann Cell Stimulation of Pancreatic Cancer Cells: A Proteomic Analysis

por Ferdoushi, Aysha, Li, Xiang, Griffin, Nathan, Faulkner, Sam, Jamaluddin, M. Fairuz B., Gao, Fangfang, Jiang, Chen Chen, van Helden, Dirk F., Tanwar, Pradeep S., Jobling, Phillip, Hondermarck, Hubert
Publicado 2020

ProNGF Expression and Targeting in Glioblastoma Multiforme

por Marsland, Mark, Dowdell, Amiee, Faulkner, Sam, Jobling, Phillip, Rush, Robert A., Gedye, Craig, Lynam, James, Griffin, Cassandra P., Baker, Mark, Marsland, Joanne, Jiang, Chen Chen, Hondermarck, Hubert
Publicado 2023

Tumor innervation and clinical outcome in pancreatic cancer

por Ferdoushi, Aysha, Griffin, Nathan, Marsland, Mark, Xu, Xiaoyue, Faulkner, Sam, Gao, Fangfang, Liu, Hui, King, Simon J., Denham, James W., van Helden, Dirk F., Jobling, Phillip, Jiang, Chen Chen, Hondermarck, Hubert
Publicado 2021

Noxa upregulation by oncogenic activation of MEK/ERK through CREB promotes autophagy in human melanoma cells

por Liu, Yi Lun, Lai, Fritz, Wilmott, James S., Yan, Xu Guang, Liu, Xiao Ying, Luan, Qi, Guo, Su Tang, Jiang, Chen Chen, Tseng, Hsin-Yi, Scolyer, Richard A., Jin, Lei, Zhang, Xu Dong
Publicado 2014

RIPK1 regulates survival of human melanoma cells upon endoplasmic reticulum stress through autophagy

por Luan, Qi, Jin, Lei, Jiang, Chen Chen, Tay, Kwang Hong, Lai, Fritz, Liu, Xiao Ying, Liu, Yi Lun, Guo, Su Tang, Li, Chun Ying, Yan, Xu Guang, Tseng, Hsin-Yi, Zhang, Xu Dong
Publicado 2015

Reactivation of ERK and Akt confers resistance of mutant BRAF colon cancer cells to the HSP90 inhibitor AUY922

por Wang, Chun Yan, Guo, Su Tang, Wang, Jia Yu, Yan, Xu Guang, Farrelly, Margaret, Zhang, Yuan Yuan, Liu, Fen, Yari, Hamed, La, Ting, Lei, Fu Xi, Jin, Lei, Zhang, Xu Dong, Jiang, Chen Chen
Publicado 2016

A Simple but Accurate Method for Evaluating Drug-Resistance in Infectious HCVcc System

por Li, Jian-Rui, Li, Wen-Jing, Cheng, Jun-Jun, Huang, Meng-Hao, Wu, Zhou-Yi, Jiang, Chen-Chen, Li, Hu, Chen, Jin-Hua, Lv, Xiao-Qin, Dong, Biao, Jiang, Jian-Dong, Peng, Zong-Gen
Publicado 2017

BRAF/MEK inhibitors promote CD47 expression that is reversible by ERK inhibition in melanoma

por Liu, Fen, Jiang, Chen Chen, Yan, Xu Guang, Tseng, Hsin-Yi, Wang, Chun Yan, Zhang, Yuan Yuan, Yari, Hamed, La, Ting, Farrelly, Margaret, Guo, Su Tang, Thorne, Rick F., Jin, Lei, Wang, Qi, Zhang, Xu Dong
Publicado 2017

INPP4B is upregulated and functions as an oncogenic driver through SGK3 in a subset of melanomas

por Chi, Meng Na, Guo, Su Tang, Wilmott, James S., Guo, Xiang Yun, Yan, Xu Guang, Wang, Chun Yan, Liu, Xiao Ying, Jin, Lei, Tseng, Hsin-Yi, Liu, Tao, Croft, Amanda, Hondermarck, Hubert, Scolyer, Richard A., Jiang, Chen Chen, Zhang, Xu Dong
Publicado 2015

Divergent projections of the prelimbic cortex mediate autism- and anxiety-like behaviors

por Luo, Yi-Fan, Lu, Lu, Song, Heng-Yi, Xu, Han, Zheng, Zhi-Wei, Wu, Zhou-Yue, Jiang, Chen-Chen, Tong, Chu, Yuan, Hao-Yang, Liu, Xiu-Xiu, Chen, Xiang, Sun, Mei-ling, Tang, Ya-Min, Fan, Heng-Yu, Han, Feng, Lu, Ying-Mei
Publicado 2023