Dual targeting of PI3K and BCL‐2 overcomes ibrutinib resistance in aggressive mantle cell lymphoma

por Ye, Haige, Huang, Shengjian, Liu, Yang, Chen, Zhihong, Wang, Michael, Jiang, Vivian Changying
Publicado 2022

The antibody drug conjugate VLS-101 targeting ROR1 is effective in CAR T-resistant mantle cell lymphoma

por Jiang, Vivian Changying, Liu, Yang, Jordan, Alexa, McIntosh, Joseph, Li, Yijing, Che, Yuxuan, Jessen, Katti A., Lannutti, Brian J., Wang, Michael
Publicado 2021

Targeting glutaminase is therapeutically effective in ibrutinib-resistant mantle cell lymphoma

por Li, Lingzhi, Nie, Lei, Jordan, Alexa, Cai, Qingsong, Liu, Yang, Li, Yijing, Che, Yuxuan, Vargas, Jovanny, Chen, Zhihong, Leeming, Angela, Wang, Wei, Yao, Yixin, Wang, Michael, Jiang, Vivian Changying
Publicado 2022

Pirtobrutinib and venetoclax combination overcomes resistance to targeted and chimeric antigen receptor T-cell therapy in aggressive mantle cell lymphoma

por Liu, Yang, Yan, Fangfang, Jiang, Vivian Changying, Li, Yijing, Che, Yuxuan, McIntosh, Joseph, Jordan, Alexa, Hou, Ian, Nie, Lei, Jin, Jingling, Wang, Wei, Lee, Heng-Huan, Yao, Yixin, Wang, Michael
Publicado 2022

Dual targeting of CDK4/6 and Bcl-2 exhibits a potent antitumor effect on mantle cell lymphoma

por Che, Yuxuan, Liu, Yang, Li, Yijing, McIntosh, Joseph M., Jordan, Alexa, Yan, Fangfang, Wang, Wei, Nie, Lei, Lee, Heng-Huan, Jin, Jingling, Yao, Yixin, Zhao, Zhongming, Jiang, Vivian Changying, Wang, Michael
Publicado 2023

Potentiation of apoptosis in drug-resistant mantle cell lymphoma cells by MCL-1 inhibitor involves downregulation of inhibitor of apoptosis proteins

por Li, Yijing, Lee, Heng-Huan, Jiang, Vivian Changying, Che, Yuxuan, McIntosh, Joseph, Jordan, Alexa, Vargas, Jovanny, Zhang, Tianci, Yan, Fangfang, Simmons, Margaret Elizabeth, Wang, Wei, Nie, Lei, Yao, Yixin, Jain, Preetesh, Wang, Michael, Liu, Yang
Publicado 2023

Targeting FcγRIIB by antagonistic antibody BI-1206 improves the efficacy of rituximab-based therapies in aggressive mantle cell lymphoma

por Jiang, Vivian Changying, Liu, Yang, Jordan, Alexa, Leeming, Angela, McIntosh, Joseph, Huang, Shengjian, Zhang, Rongjia, Cai, Qingsong, Chen, Zhihong, Li, Yijing, Che, Yuxuan, Nie, Lei, Karlsson, Ingrid, Mårtensson, Linda, Kovacek, Mathilda, Teige, Ingrid, Frendéus, Björn, Wang, Michael
Publicado 2022

TIGIT is the central player in T-cell suppression associated with CAR T-cell relapse in mantle cell lymphoma

por Jiang, Vivian Changying, Hao, Dapeng, Jain, Preetesh, Li, Yijing, Cai, Qingsong, Yao, Yixin, Nie, Lei, Liu, Yang, Jin, Jingling, Wang, Wei, Lee, Heng-Huan, Che, Yuxuan, Dai, Enyu, Han, Guangchun, Wang, Ruiping, Rai, Kunal, Futreal, Andrew, Flowers, Christopher, Wang, Linghua, Wang, Michael
Publicado 2022

Cotargeting of BTK and MALT1 overcomes resistance to BTK inhibitors in mantle cell lymphoma

por Jiang, Vivian Changying, Liu, Yang, Lian, Junwei, Huang, Shengjian, Jordan, Alexa, Cai, Qingsong, Lin, Ruitao, Yan, Fangfang, McIntosh, Joseph, Li, Yijing, Che, Yuxuan, Chen, Zhihong, Vargas, Jovanny, Badillo, Maria, Bigcal, John Nelson, Lee, Heng-Huan, Wang, Wei, Yao, Yixin, Nie, Lei, Flowers, Christopher R., Wang, Michael
Publicado 2023

Longitudinal single-cell profiling reveals molecular heterogeneity and tumor-immune evolution in refractory mantle cell lymphoma

por Zhang, Shaojun, Jiang, Vivian Changying, Han, Guangchun, Hao, Dapeng, Lian, Junwei, Liu, Yang, Zhang, Rongjia, McIntosh, Joseph, Wang, Ruiping, Dang, Minghao, Dai, Enyu, Wang, Yuanxin, Santos, David, Badillo, Maria, Leeming, Angela, Chen, Zhihong, Hartig, Kimberly, Bigcal, John, Zhou, Jia, Kanagal-Shamanna, Rashmi, Ok, Chi Young, Lee, Hun, Steiner, Raphael E., Zhang, Jianhua, Song, Xingzhi, Nair, Ranjit, Ahmed, Sairah, Rodriquez, Alma, Thirumurthi, Selvi, Jain, Preetesh, Wagner-Bartak, Nicolaus, Hill, Holly, Nomie, Krystle, Flowers, Christopher, Futreal, Andrew, Wang, Linghua, Wang, Michael
Publicado 2021