A Modified Fibronectin Type III Domain-Conjugated, Long-Acting Pan-Coronavirus Fusion Inhibitor with Extended Half-Life

por Duan, Qianyu, Xia, Shuai, Jiao, Fanke, Wang, Qian, Wang, Rui, Lu, Lu, Jiang, Shibo, Xu, Wei
Publicado 2022

25-Hydroxycholesterol-Conjugated EK1 Peptide with Potent and Broad-Spectrum Inhibitory Activity against SARS-CoV-2, Its Variants of Concern, and Other Human Coronaviruses

por Lan, Qiaoshuai, Wang, Chao, Zhou, Jie, Wang, Lijue, Jiao, Fanke, Zhang, Yanbo, Cai, Yanxing, Lu, Lu, Xia, Shuai, Jiang, Shibo
Publicado 2021

Lipopeptide-based pan-CoV fusion inhibitors potently inhibit HIV-1 infection

por Lan, Qiaoshuai, Pu, Jing, Cai, Yanxing, Zhou, Jie, Wang, Lijue, Jiao, Fanke, Xu, Wei, Wang, Qian, Xia, Shuai, Lu, Lu, Jiang, Shibo
Publicado 2021

Structure-based evidence for the enhanced transmissibility of the dominant SARS-CoV-2 B.1.1.7 variant (Alpha)

por Xia, Shuai, Wen, Zuoling, Wang, Lijue, Lan, Qiaoshuai, Jiao, Fanke, Tai, Linhua, Wang, Qian, Sun, Fei, Jiang, Shibo, Lu, Lu, Zhu, Yun
Publicado 2021

SARS-CoV-2 Omicron subvariants exhibit distinct fusogenicity, but similar sensitivity, to pan-CoV fusion inhibitors

por Xia, Shuai, Wang, Lijue, Jiao, Fanke, Yu, Xueying, Xu, Wei, Huang, Ziqi, Li, Xicheng, Wang, Qian, Zhu, Yun, Man, Qiuhong, Jiang, Shibo, Lu, Lu
Publicado 2023

An inducible hACE2 transgenic mouse model recapitulates SARS-CoV-2 infection and pathogenesis in vivo

por Liu, Kuo, Tang, Muxue, Xu, Wei, Meng, Xinfeng, Jin, Hengwei, Han, Maoying, Pu, Jing, Li, Yutang, Jiao, Fanke, Sun, Ruilin, Shen, Ruling, Lui, Kathy O., Lu, Lu, Zhou, Bin
Publicado 2023

A Palmitic Acid-Conjugated, Peptide-Based pan-CoV Fusion Inhibitor Potently Inhibits Infection of SARS-CoV-2 Omicron and Other Variants of Concern

por Lan, Qiaoshuai, Chan, Jasper Fuk-Woo, Xu, Wei, Wang, Lijue, Jiao, Fanke, Zhang, Guangxu, Pu, Jing, Zhou, Jie, Xia, Shuai, Lu, Lu, Yuen, Kwok-Yung, Jiang, Shibo, Wang, Qian
Publicado 2022

Peptide-based pan-CoV fusion inhibitors maintain high potency against SARS-CoV-2 Omicron variant

por Xia, Shuai, Chan, Jasper Fuk-Woo, Wang, Lijue, Jiao, Fanke, Chik, Kenn Ka-Heng, Chu, Hin, Lan, Qiaoshuai, Xu, Wei, Wang, Qian, Wang, Chao, Yuen, Kwok-Yung, Lu, Lu, Jiang, Shibo
Publicado 2022

Structural and functional basis for pan-CoV fusion inhibitors against SARS-CoV-2 and its variants with preclinical evaluation

por Xia, Shuai, Lan, Qiaoshuai, Zhu, Yun, Wang, Chao, Xu, Wei, Li, Yutang, Wang, Lijue, Jiao, Fanke, Zhou, Jie, Hua, Chen, Wang, Qian, Cai, Xia, Wu, Yang, Gao, Jie, Liu, Huan, Sun, Ge, Münch, Jan, Kirchhoff, Frank, Yuan, Zhenghong, Xie, Youhua, Sun, Fei, Jiang, Shibo, Lu, Lu
Publicado 2021