Enzyme/Nanocopper Hybrid Nanozymes: Modulating Enzyme-like Activity by the Protein Structure for Biosensing and Tumor Catalytic Therapy

por Losada-Garcia, Noelia, Jimenez-Alesanco, Ana, Velazquez-Campoy, Adrian, Abian, Olga, Palomo, Jose M.
Publicado 2021

The Paralogue of the Intrinsically Disordered Nuclear Protein 1 Has a Nuclear Localization Sequence that Binds to Human Importin α3

por Neira, José L., Rizzuti, Bruno, Jiménez-Alesanco, Ana, Abián, Olga, Velázquez-Campoy, Adrián, Iovanna, Juan L.
Publicado 2020

A Phosphorylation-Induced Switch in the Nuclear Localization Sequence of the Intrinsically Disordered NUPR1 Hampers Binding to Importin

por Neira, José L., Rizzuti, Bruno, Jiménez-Alesanco, Ana, Palomino-Schätzlein, Martina, Abián, Olga, Velázquez-Campoy, Adrián, Iovanna, Juan L.
Publicado 2020

Structural stability of SARS-CoV-2 3CLpro and identification of quercetin as an inhibitor by experimental screening

por Abian, Olga, Ortega-Alarcon, David, Jimenez-Alesanco, Ana, Ceballos-Laita, Laura, Vega, Sonia, Reyburn, Hugh T., Rizzuti, Bruno, Velazquez-Campoy, Adrian
Publicado 2020

Biosourced All-Acrylic ABA Block Copolymers with Lactic Acid-Based Soft Phase

por Bensabeh, Nabil, Jiménez-Alesanco, Ana, Liblikas, Ilme, Ronda, Juan C., Cádiz, Virginia, Galià, Marina, Vares, Lauri, Abián, Olga, Lligadas, Gerard
Publicado 2020

Sub-Micromolar Inhibition of SARS-CoV-2 3CLpro by Natural Compounds

por Rizzuti, Bruno, Ceballos-Laita, Laura, Ortega-Alarcon, David, Jimenez-Alesanco, Ana, Vega, Sonia, Grande, Fedora, Conforti, Filomena, Abian, Olga, Velazquez-Campoy, Adrian
Publicado 2021

Repositioning small molecule drugs as allosteric inhibitors of the BFT‐3 toxin from enterotoxigenic Bacteroides fragilis

por Jimenez‐Alesanco, Ana, Eckhard, Ulrich, Asencio del Rio, Marta, Vega, Sonia, Guevara, Tibisay, Velazquez‐Campoy, Adrian, Gomis‐Rüth, Francesc Xavier, Abian, Olga
Publicado 2022

Rutin Is a Low Micromolar Inhibitor of SARS-CoV-2 Main Protease 3CLpro: Implications for Drug Design of Quercetin Analogs

por Rizzuti, Bruno, Grande, Fedora, Conforti, Filomena, Jimenez-Alesanco, Ana, Ceballos-Laita, Laura, Ortega-Alarcon, David, Vega, Sonia, Reyburn, Hugh T., Abian, Olga, Velazquez-Campoy, Adrian
Publicado 2021

Autochthonous Peruvian Natural Plants as Potential SARS-CoV-2 M(pro) Main Protease Inhibitors

por Peralta-Moreno, Maria Nuria, Anton-Muñoz, Vanessa, Ortega-Alarcon, David, Jimenez-Alesanco, Ana, Vega, Sonia, Abian, Olga, Velazquez-Campoy, Adrian, Thomson, Timothy M., Granadino-Roldán, José Manuel, Machicado, Claudia, Rubio-Martinez, Jaime
Publicado 2023

Discovery of Diverse Natural Products as Inhibitors of SARS-CoV-2 M(pro) Protease through Virtual Screening

por Rubio-Martínez, Jaime, Jiménez-Alesanco, Ana, Ceballos-Laita, Laura, Ortega-Alarcón, David, Vega, Sonia, Calvo, Cristina, Benítez, Cristina, Abian, Olga, Velázquez-Campoy, Adrián, Thomson, Timothy M., Granadino-Roldán, José Manuel, Gómez-Gutiérrez, Patricia, Pérez, Juan J.
Publicado 2021

l-Arginine Improves Solubility and ANTI SARS-CoV-2 Mpro Activity of Rutin but Not the Antiviral Activity in Cells

por Sancineto, Luca, Ostacolo, Carmine, Ortega-Alarcon, David, Jimenez-Alesanco, Ana, Ceballos-Laita, Laura, Vega, Sonia, Abian, Olga, Velazquez-Campoy, Adrian, Moretti, Silvia, Dabrowska, Agnieszka, Botwina, Pawel, Synowiec, Aleksandra, Kula-Pacurar, Anna, Pyrc, Krzysztof, Iraci, Nunzio, Santi, Claudio
Publicado 2021

ZZW-115–dependent inhibition of NUPR1 nuclear translocation sensitizes cancer cells to genotoxic agents

por Lan, Wenjun, Santofimia-Castaño, Patricia, Swayden, Mirna, Xia, Yi, Zhou, Zhengwei, Audebert, Stephane, Camoin, Luc, Huang, Can, Peng, Ling, Jiménez-Alesanco, Ana, Velázquez-Campoy, Adrián, Abián, Olga, Lomberk, Gwen, Urrutia, Raul, Rizzuti, Bruno, Geli, Vincent, Soubeyran, Philippe, Neira, José L., Iovanna, Juan
Publicado 2020

Seleno-Functionalization of Quercetin Improves the Non-Covalent Inhibition of M(pro) and Its Antiviral Activity in Cells against SARS-CoV-2

por Mangiavacchi, Francesca, Botwina, Pawel, Menichetti, Elena, Bagnoli, Luana, Rosati, Ornelio, Marini, Francesca, Fonseca, Sérgio F., Abenante, Laura, Alves, Diego, Dabrowska, Agnieszka, Kula-Pacurar, Anna, Ortega-Alarcon, David, Jimenez-Alesanco, Ana, Ceballos-Laita, Laura, Vega, Sonia, Rizzuti, Bruno, Abian, Olga, Lenardão, Eder J., Velazquez-Campoy, Adrian, Pyrc, Krzysztof, Sancineto, Luca, Santi, Claudio
Publicado 2021