Targeting the Intrinsic Apoptosis Pathway: A Window of Opportunity for Prostate Cancer

por Westaby, Daniel, Jimenez-Vacas, Juan M., Padilha, Ana, Varkaris, Andreas, Balk, Steven P., de Bono, Johann S., Sharp, Adam
Publicado 2021

THU550 The Splicing Factor SRSF6 Regulates Androgen Receptor Activity And Represents A Potential Therapeutic Target In Prostate Cancer

por Luque, Raul M, Montero-Hidalgo, Antonio J, Gomez-Gomez, Enrique, Olmos, David, Gahete, Manuel D, Jimenez-Vacas, Juan M
Publicado 2023

Somatostatin, Cortistatin and Their Receptors Exert Antitumor Actions in Androgen-Independent Prostate Cancer Cells: Critical Role of Endogenous Cortistatin

por Sáez-Martínez, Prudencio, Porcel-Pastrana, Francisco, Pérez-Gómez, Jesús M., Pedraza-Arévalo, Sergio, Gómez-Gómez, Enrique, Jiménez-Vacas, Juan M., Gahete, Manuel D., Luque, Raúl M.
Publicado 2022

Clinical association of metabolic syndrome, C‐reactive protein and testosterone levels with clinically significant prostate cancer

por Gómez‐Gómez, Enrique, Carrasco‐Valiente, Julia, Campos‐Hernández, Juan Pablo, Blanca‐Pedregosa, Ana Maria, Jiménez‐Vacas, Juan Manuel, Ruiz‐García, Jesus, Valero‐Rosa, Jose, Luque, Raul Miguel, Requena‐Tapia, María José
Publicado 2018

Comparative Cytotoxic Activity of Hydroxytyrosol and Its Semisynthetic Lipophilic Derivatives in Prostate Cancer Cells

por León-González, Antonio J., Sáez-Martínez, Prudencio, Jiménez-Vacas, Juan M., Herrero-Aguayo, Vicente, Montero-Hidalgo, Antonio J., Gómez-Gómez, Enrique, Madrona, Andrés, Castaño, Justo P., Espartero, José L., Gahete, Manuel D., Luque, Raúl M.
Publicado 2021

Observational study comparing the accuracy/variability between the ERSPC and the PCPT risk calculators for the prediction of significant prostate cancer in patients with PSA <10 ng...

por Gomez Gomez, Enrique, Salamanca Bustos, Juan José, Carrasco Valiente, Julia, Fernandez Rueda, Jose Luis, Blanca, Ana, Valero Rosa, José, Bravo Arrebola, Ines, Marquez López, Javier, Jimenez Vacas, Juan Manuel, Luque, Raul Miguel, Requena Tapia, Maria José
Publicado 2019

SF3B1 inhibition disrupts malignancy and prolongs survival in glioblastoma patients through BCL2L1 splicing and mTOR/ß-catenin pathways imbalances

por Fuentes-Fayos, Antonio C., Pérez-Gómez, Jesús M., E. G-García, Miguel, Jiménez-Vacas, Juan M., Blanco-Acevedo, Cristóbal, Sánchez-Sánchez, Rafael, Solivera, Juan, Breunig, Joshua J., Gahete, Manuel D., Castaño, Justo P., Luque, Raúl M.
Publicado 2022

Unleashing the Diagnostic, Prognostic and Therapeutic Potential of the Neuronostatin/GPR107 System in Prostate Cancer

por Sáez-Martínez, Prudencio, Jiménez-Vacas, Juan M., León-González, Antonio J., Herrero-Aguayo, Vicente, Montero Hidalgo, Antonio J., Gómez-Gómez, Enrique, Sánchez-Sánchez, Rafael, Requena-Tapia, María J., Castaño, Justo P., Gahete, Manuel D., Luque, Raúl M.
Publicado 2020

Prostate-Specific Membrane Antigen Expression and Response to DNA Damaging Agents in Prostate Cancer

por Sheehan, Beshara, Neeb, Antje, Buroni, Lorenzo, Paschalis, Alec, Riisnaes, Ruth, Gurel, Bora, Gil, Veronica, Miranda, Susana, Crespo, Mateus, Guo, Christina, Jiménez Vacas, Juan, Figueiredo, Ines, Ferreira, Ana, Welti, Jon, Yuan, Wei, Carreira, Suzanne, Sharp, Adam, de Bono, Johann
Publicado 2022

THU080 Splicing Machinery Dysregulation As A Source Of Novel Diagnostic, Prognostic And Therapeutic Targets In Craniopharyngiomas

por Fuentes-Fayos, Antonio C, Garcia-Garcia, Miguel E, Cano, David, Martínez-Fuentes, Antonio J, Di Caro, Isidoro, Gahete, Manuel D, Castaño, Justo P, Martínez-Barbera, Juan P, Soto-Moreno, Alfonso, Galvez-Moreno, Maria A, Jimenez-Vacas, Juan M, Luque, Raul M
Publicado 2023

Plasma ghrelin O‐acyltransferase (GOAT) enzyme levels: A novel non‐invasive diagnosis tool for patients with significant prostate cancer

por Gómez‐Gómez, Enrique, Jiménez‐Vacas, Juan M., Carrasco‐Valiente, Julia, Herrero‐Aguayo, Vicente, Blanca‐Pedregosa, Ana M., León‐González, Antonio J., Valero‐Rosa, José, Fernández‐Rueda, José L., González‐Serrano, Teresa, López‐Miranda, José, Gahete, Manuel D., Castaño, Justo P., Requena‐Tapia, María J., Luque, Raúl M.
Publicado 2018

Clinical Utility of Ghrelin-O-Acyltransferase (GOAT) Enzyme as a Diagnostic Tool and Potential Therapeutic Target in Prostate Cancer

por Jiménez-Vacas, Juan M., Gómez-Gómez, Enrique, Montero-Hidalgo, Antonio J., Herrero-Aguayo, Vicente, L-López, Fernando, Sánchez-Sánchez, Rafael, Guler, Ipek, Blanca, Ana, Méndez-Vidal, María José, Carrasco, Julia, Lopez-Miranda, José, Requena-Tapia, María J., Castaño, Justo P., Gahete, Manuel D., Luque, Raúl M.
Publicado 2019

Splicing machinery dysregulation drives glioblastoma development/aggressiveness: oncogenic role of SRSF3

por Fuentes-Fayos, Antonio C, Vázquez-Borrego, Mari C, Jiménez-Vacas, Juan M, Bejarano, Leire, Pedraza-Arévalo, Sergio, L.-López, Fernando, Blanco-Acevedo, Cristóbal, Sánchez-Sánchez, Rafael, Reyes, Oscar, Ventura, Sebastián, Solivera, Juan, Breunig, Joshua J, Blasco, María A, Gahete, Manuel D, Castaño, Justo P, Luque, Raúl M
Publicado 2020

SUN-LB056 The Pharmacological Blockade of the Splicing Factor SF3B1 Exerts Antitumor Actions in Different Endocrine-Related Cancers

por Gahete, Manuel, Jiménez-Vacas, Juan, Lopez-Canovas, Juan, Vazquez-Borrego, Mari, Pedraza-Arevalo, Sergio, del Río-Moreno, Mercedes, Herrero-Aguayo, Vicente, Saez-Martinez, Prudencio, Montero-Hidalgo, Antonio, Blazquez-Encinas, Ricardo, Lara-Lopez, Araceli, Pérez-Gómez, Jesus, Gomez-Gomez, Enrique, Herrera-Martínez, Aura, Soto-Moreno, Alfonso, Castano, Justo, Luque, Raul
Publicado 2019

Oncogenic Role of Secreted Engrailed Homeobox 2 (EN2) in Prostate Cancer

por Gómez-Gómez, Enrique, Jiménez-Vacas, Juan M., Pedraza-Arévalo, Sergio, López-López, Fernando, Herrero-Aguayo, Vicente, Hormaechea-Agulla, Daniel, Valero-Rosa, José, Ibáñez-Costa, Alejandro, León-González, Antonio J., Sánchez-Sánchez, Rafael, González-Serrano, Teresa, Requena-Tapia, Maria J., Castaño, Justo P., Carrasco-Valiente, Julia, Gahete, Manuel D., Luque, Raúl M.
Publicado 2019

The catalytic subunit of DNA-PK regulates transcription and splicing of AR in advanced prostate cancer

por Adamson, Beth, Brittain, Nicholas, Walker, Laura, Duncan, Ruaridh, Luzzi, Sara, Rescigno, Pasquale, Smith, Graham, McGill, Suzanne, Burchmore, Richard J.S., Willmore, Elaine, Hickson, Ian, Robson, Craig N., Bogdan, Denisa, Jimenez-Vacas, Juan M., Paschalis, Alec, Welti, Jonathan, Yuan, Wei, McCracken, Stuart R., Heer, Rakesh, Sharp, Adam, de Bono, Johann S., Gaughan, Luke
Publicado 2023

The oncogenic role of the In1-ghrelin splicing variant in prostate cancer aggressiveness

por Hormaechea-Agulla, Daniel, Gahete, Manuel D., Jiménez-Vacas, Juan M., Gómez-Gómez, Enrique, Ibáñez-Costa, Alejandro, L-López, Fernando, Rivero-Cortés, Esther, Sarmento-Cabral, André, Valero-Rosa, José, Carrasco-Valiente, Julia, Sánchez-Sánchez, Rafael, Ortega-Salas, Rosa, Moreno, María M., Tsomaia, Natia, Swanson, Steve M., Culler, Michael D., Requena, María J., Castaño, Justo P., Luque, Raúl M.
Publicado 2017

Dysregulation of the miRNome unveils a crosstalk between obesity and prostate cancer: miR-107 asa personalized diagnostic and therapeutic tool

por Herrero-Aguayo, Vicente, Sáez-Martínez, Prudencio, Jiménez-Vacas, Juan M., Moreno-Montilla, M. Trinidad, Montero-Hidalgo, Antonio J., Pérez-Gómez, Jesús M., López-Canovas, Juan L., Porcel-Pastrana, Francisco, Carrasco-Valiente, Julia, Anglada, Francisco J., Gómez-Gómez, Enrique, Yubero-Serrano, Elena M., Ibañez-Costa, Alejandro, Herrera-Martínez, Aura D., Sarmento-Cabral, André, Gahete, Manuel D., Luque, Raúl M.
Publicado 2022

Metformin and simvastatin exert additive antitumour effects in glioblastoma via senescence-state: clinical and translational evidence

por Fuentes-Fayos, Antonio C., G-García, Miguel E., Pérez-Gómez, Jesús M., Montero-Hidalgo, Antonio J., Martín-Colom, Julia, Doval-Rosa, Carlos, Blanco-Acevedo, Cristóbal, Torres, Encarnación, Toledano-Delgado, Álvaro, Sánchez-Sánchez, Rafael, Peralbo-Santaella, Esther, Ortega-Salas, Rosa M., Jiménez-Vacas, Juan M., Tena-Sempere, Manuel, López, Miguel, Castaño, Justo P., Gahete, Manuel D., Solivera, Juan, Luque, Raúl M.
Publicado 2023

Dysregulation of the splicing machinery is directly associated to aggressiveness of prostate cancer

por Jiménez-Vacas, Juan M., Herrero-Aguayo, Vicente, Montero-Hidalgo, Antonio J., Gómez-Gómez, Enrique, Fuentes-Fayos, Antonio C., León-González, Antonio J., Sáez-Martínez, Prudencio, Alors-Pérez, Emilia, Pedraza-Arévalo, Sergio, González-Serrano, Teresa, Reyes, Oscar, Martínez-López, Ana, Sánchez-Sánchez, Rafael, Ventura, Sebastián, Yubero-Serrano, Elena M., Requena-Tapia, María J., Castaño, Justo P., Gahete, Manuel D., Luque, Raúl M.
Publicado 2020