hERG1 channel subunit composition mediates proton inhibition of rapid delayed rectifier potassium current (I(Kr)) in cardiomyocytes derived from hiPSCs

por Ukachukwu, Chiamaka U., Jimenez-Vazquez, Eric N., Jain, Abhilasha, Jones, David K.
Publicado 2022

The ERG1 K(+) Channel and Its Role in Neuronal Health and Disease

por Sanchez-Conde, Francisco G., Jimenez-Vazquez, Eric N., Auerbach, David S., Jones, David K.
Publicado 2022

Human perinatal stem cell derived extracellular matrix enables rapid maturation of hiPSC-CM structural and functional phenotypes

por Block, Travis, Creech, Jeffery, da Rocha, Andre Monteiro, Marinkovic, Milos, Ponce-Balbuena, Daniela, Jiménez-Vázquez, Eric N., Griffey, Sy, Herron, Todd J.
Publicado 2020

KCNH2 encodes a nuclear-targeted polypeptide that mediates hERG1 channel gating and expression

por Jain, Abhilasha, Stack, Olivia, Ghodrati, Saba, Sanchez-Conde, Francisco G., Ukachukwu, Chiamaka U., Salwi, Shreya, Jimenez-Vazquez, Eric N., Jones, David K.
Publicado 2023

A multiscale approach for bridging the gap between potency, efficacy, and safety of small molecules directed at membrane proteins

por Aguayo-Ortiz, Rodrigo, Creech, Jeffery, Jiménez-Vázquez, Eric N., Guerrero-Serna, Guadalupe, Wang, Nulang, da Rocha, Andre Monteiro, Herron, Todd J., Espinoza-Fonseca, L. Michel
Publicado 2021

In vitro model of ischemic heart failure using human induced pluripotent stem cell–derived cardiomyocytes

por Davis, Justin, Chouman, Ahmad, Creech, Jeffery, Monteiro da Rocha, Andre, Ponce-Balbuena, Daniela, Jimenez Vazquez, Eric N., Nichols, Ruthann, Lozhkin, Andrey, Madamanchi, Nageswara R., Campbell, Katherine F., Herron, Todd J.
Publicado 2021

SNTA1 gene rescues ion channel function and is antiarrhythmic in cardiomyocytes derived from induced pluripotent stem cells from muscular dystrophy patients

por Jimenez-Vazquez, Eric N, Arad, Michael, Macías, Álvaro, Vera-Pedrosa, Maria L, Cruz, Francisco Miguel, Gutierrez, Lilian K, Cuttitta, Ashley J, Monteiro da Rocha, André, Herron, Todd J, Ponce-Balbuena, Daniela, Guerrero-Serna, Guadalupe, Binah, Ofer, Michele, Daniel E, Jalife, José
Publicado 2022