Premature polyadenylation of MAGI3 is associated with diminished N(6)-methyladenosine in its large internal exon

por Ni, Thomas K., Elman, Jessica S., Jin, Dexter X., Gupta, Piyush B., Kuperwasser, Charlotte
Publicado 2018

Perturbation-Expression Analysis Identifies RUNX1 as a Regulator of Human Mammary Stem Cell Differentiation

por Sokol, Ethan S., Sanduja, Sandhya, Jin, Dexter X., Miller, Daniel H., Mathis, Robert A., Gupta, Piyush B.
Publicado 2015

Cancer-specific PERK signaling drives invasion and metastasis through CREB3L1

por Feng, Yu-Xiong, Jin, Dexter X., Sokol, Ethan S., Reinhardt, Ferenc, Miller, Daniel H., Gupta, Piyush B.
Publicado 2017

Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing

por Elman, Jessica S., Ni, Thomas K., Mengwasser, Kristen E., Jin, Dexter, Wronski, Ania, Elledge, Stephen J., Kuperwasser, Charlotte
Publicado 2019

PARP Inhibitor Insensitivity to BRCA1/2 Monoallelic Mutations in Microsatellite Instability-High Cancers

por Sokol, Ethan S., Jin, Dexter X., Fine, Alexander, Trabucco, Sally E., Maund, Sophia, Frampton, Garrett, Molinero, Luciana, Antonarakis, Emmanuel S.
Publicado 2022

A pan-sarcoma landscape of telomeric content shows that alterations in RAD51B and GID4 are associated with higher telomeric content

por Sharaf, Radwa, Jin, Dexter X., Grady, John, Napier, Christine, Ebot, Ericka, Frampton, Garrett M., Albacker, Lee A., Thomas, David M., Montesion, Meagan
Publicado 2023

BCL11B Drives Human Mammary Stem Cell Self-Renewal In Vitro by Inhibiting Basal Differentiation

por Miller, Daniel H., Jin, Dexter X., Sokol, Ethan S., Cabrera, Janel R., Superville, Daphne A., Gorelov, Rebecca A., Kuperwasser, Charlotte, Gupta, Piyush B.
Publicado 2018

Gene partners of the EWSR1 fusion may represent molecularly distinct entities

por Walker, Victoria, Jin, Dexter X., Millis, Sherri Z., Nasri, Elham, Corao-Uribe, Diana A., Tan, Aik Choon, Fridley, Brooke L., Chen, James L., Seligson, Nathan D.
Publicado 2023

Comprehensive Genomic Profiling of Carcinoma of Unknown Primary Origin: Retrospective Molecular Classification Considering the CUPISCO Study Design

por Ross, Jeffrey S., Sokol, Ethan S., Moch, Holger, Mileshkin, Linda, Baciarello, Giulia, Losa, Ferran, Beringer, Andreas, Thomas, Marlene, Elvin, Julia A., Ngo, Nhu, Jin, Dexter X., Krämer, Alwin
Publicado 2020

Genetic Heterogeneity and Tissue-specific Patterns of Tumors with Multiple PIK3CA Mutations

por Sivakumar, Smruthy, Jin, Dexter X., Rathod, Ruchita, Ross, Jeffrey, Cantley, Lewis C., Scaltriti, Maurizio, Chen, Jessica W., Hutchinson, Katherine E., Wilson, Timothy R., Sokol, Ethan S., Vasan, Neil
Publicado 2023

First results of the EORTC-SPECTA/Arcagen study exploring the genomics of rare cancers in collaboration with the European reference network EURACAN

por Morfouace, Marie, Stevovic, Aleksandra, Vinches, Marie, Golfinopoulos, Vassilis, Jin, Dexter X., Holmes, Oliver, Erlich, Rachel, Fayette, Jerome, Croce, Sabrina, Ray-Coquard, Isabelle, Girard, Nicolas, Blay, Jean-Yves
Publicado 2020

Drivers of genomic loss of heterozygosity in leiomyosarcoma are distinct from carcinomas

por Seligson, Nathan D., Tang, Joy, Jin, Dexter X., Bennett, Monica P., Elvin, Julia A., Graim, Kiley, Hays, John L., Millis, Sherri Z., Miles, Wayne O., Chen, James L.
Publicado 2022

Breast tissue regeneration is driven by cell-matrix interactions coordinating multi-lineage stem cell differentiation through DDR1

por Rauner, Gat, Jin, Dexter X., Miller, Daniel H., Gierahn, Todd M., Li, Carman M., Sokol, Ethan S., Feng, Yu-Xiong, Mathis, Robert A., Love, J. Christopher, Gupta, Piyush B., Kuperwasser, Charlotte
Publicado 2021

Homologous Recombination Deficiency Landscape of Breast Cancers and Real-World Effectiveness of Poly ADP-Ribose Polymerase Inhibitors in Patients With Somatic BRCA1/2, Germline PAL...

por Batalini, Felipe, Madison, Russell W., Sokol, Ethan S., Jin, Dexter X., Chen, Kuei-Ting, Decker, Brennan, Pavlick, Dean C., Frampton, Garrett M., Wulf, Gerburg M., Garber, Judy E., Oxnard, Geoffrey, Schrock, Alexa B., Tung, Nadine M.
Publicado 2023

A Novel HRD Signature Is Predictive of FOLFIRINOX Benefit in Metastatic Pancreatic Cancer

por Chen, Kuei-Ting, Madison, Russell, Moore, Jay, Jin, Dexter, Fleischmann, Zoe, Newberg, Justin, Schrock, Alexa, Bhardwaj, Neeru, Lofgren, Katherine T, He, Jie, Frampton, Garrett, Hegde, Priti, Fabrizio, David, Pishvaian, Michael J, Ebot, Ericka, Singhi, Aatur, Sokol, Ethan
Publicado 2023

Association of CD274 (PD-L1) Copy Number Changes with Immune Checkpoint Inhibitor Clinical Benefit in Non-Squamous Non-Small Cell Lung Cancer

por Murugesan, Karthikeyan, Jin, Dexter X, Comment, Leah A, Fabrizio, David, Hegde, Priti S, Elvin, Julia A, Alexander, Brian, Levy, Mia A, Frampton, Garrett M, Montesion, Meagan, Roychowdhury, Sameek, Kurzrock, Razelle, Ross, Jeffrey S, Albacker, Lee A, Huang, Richard S P
Publicado 2022

Genomic Biomarkers and Genome-Wide Loss-of-Heterozygosity Scores in Metastatic Prostate Cancer Following Progression on Androgen-Targeting Therapies

por Zurita, Amado J., Graf, Ryon P., Villacampa, Guillermo, Raskina, Kira, Sokol, Ethan, Jin, Dexter, Antonarakis, Emmanuel S., Li, Gerald, Huang, Richard S. P., Casanova-Salas, Irene, Vivancos, Ana, Carles, Joan, Ross, Jeffrey S., Schrock, Alexa B., Oxnard, Geoffrey R., Mateo, Joaquin
Publicado 2022

Tissue and liquid biopsy profiling reveal convergent tumor evolution and therapy evasion in breast cancer

por Sivakumar, Smruthy, Jin, Dexter X., Tukachinsky, Hanna, Murugesan, Karthikeyan, McGregor, Kimberly, Danziger, Natalie, Pavlick, Dean, Gjoerup, Ole, Ross, Jeffrey S., Harmon, Robert, Chung, Jon, Decker, Brennan, Dennis, Lucas, Frampton, Garrett M., Molinero, Luciana, Oesterreich, Steffi, Venstrom, Jeffrey M., Oxnard, Geoffrey R., Hegde, Priti S., Sokol, Ethan S.
Publicado 2022

Genomic profiling of solid tumors harboring BRD4-NUT and response to immune checkpoint inhibitors

por Riess, Jonathan W., Rahman, Shaila, Kian, Waleed, Edgerly, Claire, Heilmann, Andreas M., Madison, Russell, Ramkissoon, Shakti H., Klaitman, Shai Shlomi, Chung, Jon H., Trabucco, Sally E., Jin, Dexter X., Alexander, Brian M., Klempner, Samuel J., Albacker, Lee A., Frampton, Garrett M., Roisman, Laila C., Miller, Vincent A., Ross, Jeffrey S., Schrock, Alexa B., Gregg, Jeffrey P., Peled, Nir, Sokol, Ethan S., Ali, Siraj M.
Publicado 2021

Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma

por Gounder, Mrinal M., Agaram, Narasimhan P., Trabucco, Sally E., Robinson, Victoria, Ferraro, Richard A., Millis, Sherri Z., Krishnan, Anita, Lee, Jessica, Attia, Steven, Abida, Wassim, Drilon, Alexander, Chi, Ping, Angelo, Sandra P. D’, Dickson, Mark A., Keohan, Mary Lou, Kelly, Ciara M., Agulnik, Mark, Chawla, Sant P., Choy, Edwin, Chugh, Rashmi, Meyer, Christian F., Myer, Parvathi A., Moore, Jessica L., Okimoto, Ross A., Pollock, Raphael E., Ravi, Vinod, Singh, Arun S., Somaiah, Neeta, Wagner, Andrew J., Healey, John H., Frampton, Garrett M., Venstrom, Jeffrey M., Ross, Jeffrey S., Ladanyi, Marc, Singer, Samuel, Brennan, Murray F., Schwartz, Gary K., Lazar, Alexander J., Thomas, David M., Maki, Robert G., Tap, William D., Ali, Siraj M., Jin, Dexter X.
Publicado 2022