Analysis of Longitudinal‐Ordered Categorical Data for Muscle Spasm Adverse Event of Vismodegib: Comparison Between Different Pharmacometric Models

por Lu, Tong, Yang, Yujie, Jin, Jin Y., Kågedal, Matts
Publicado 2020

Update to improve reproducibility and interpretability: A response to “Machine Learning for Tumor Growth Inhibition”

por Chan, Phyllis, Lu, James, Bruno, René, Jin, Jin Y.
Publicado 2022

Challenges and Opportunities in Dose Finding in Oncology and Immuno‐oncology

por Ji, Yan, Jin, Jin Y., Hyman, David M., Kim, Geoffrey, Suri, Ajit
Publicado 2018

Application of Machine Learning for Tumor Growth Inhibition – Overall Survival Modeling Platform

por Chan, Phyllis, Zhou, Xiaofei, Wang, Nina, Liu, Qi, Bruno, René, Jin, Jin Y.
Publicado 2020

A disease model predicting placebo response and remission status of patients with ulcerative colitis using modified Mayo score

por Moein, Anita, Langenhorst, Jurgen, Plan, Elodie L., Jin, Jin Y., Kågedal, Matts, Kassir, Nastya
Publicado 2023

Multistate model for pharmacometric analyses of overall survival in HER2‐negative breast cancer patients treated with docetaxel

por Krishnan, Sreenath M., Friberg, Lena E., Bruno, René, Beyer, Ulrich, Jin, Jin Y., Karlsson, Mats O.
Publicado 2021

Short‐Term Efficacy Reliably Predicts Long‐Term Clinical Benefit in Rheumatoid Arthritis Clinical Trials as Demonstrated by Model‐Based Meta‐Analysis

por Wang, Yehong, Zhu, Rui, Xiao, Jim, Davis, John C., Mandema, Jaap W., Jin, Jin Y., Tang, Meina T.
Publicado 2015

Pharmacokinetics and pharmacodynamic effect of crenezumab on plasma and cerebrospinal fluid beta-amyloid in patients with mild-to-moderate Alzheimer’s disease

por Yoshida, Kenta, Moein, Anita, Bittner, Tobias, Ostrowitzki, Susanne, Lin, Helen, Honigberg, Lee, Jin, Jin Y., Quartino, Angelica
Publicado 2020

Assessment of cytochrome P450 3A4-mediated drug–drug interactions for ipatasertib using a fit-for-purpose physiologically based pharmacokinetic model

por Jing, Jing, Chen, Yuan, Musib, Luna, Jin, Jin Y., Cheung, Kit Wun Kathy, Yoshida, Kenta, Sane, Rucha
Publicado 2022

Tumor Time‐Course Predicts Overall Survival in Non‐Small Cell Lung Cancer Patients Treated with Atezolizumab: Dependency on Follow‐Up Time

por Netterberg, Ida, Bruno, René, Chen, Ya‐Chi, Winter, Helen, Li, Chi‐Chung, Jin, Jin Y., Friberg, Lena E.
Publicado 2020

Time‐to‐Event Modeling of Peripheral Neuropathy: Platform Analysis of Eight Valine‐Citrulline‐Monomethylauristatin E Antibody–Drug Conjugates

por Kågedal, Matts, Samineni, Divya, Gillespie, William R., Lu, Dan, Fine, Bernard M., Girish, Sandhya, Li, Chunze, Jin, Jin Y.
Publicado 2019

Population pharmacokinetic and covariate analyses of intravenous trastuzumab (Herceptin(®)), a HER2-targeted monoclonal antibody, in patients with a variety of solid tumors

por Quartino, Angelica L., Li, Hanbin, Kirschbrown, Whitney P., Mangat, Ranvir, Wada, D. Russell, Garg, Amit, Jin, Jin Y., Lum, Bert
Publicado 2018

Impact of Physiologically Based Pharmacokinetics, Population Pharmacokinetics and Pharmacokinetics/Pharmacodynamics in the Development of Antibody‐Drug Conjugates

por Li, Chunze, Chen, Shang‐Chiung, Chen, Yuan, Girish, Sandhya, Kågedal, Matts, Lu, Dan, Lu, Tong, Samineni, Divya, Jin, Jin Y.
Publicado 2020

A Pharmacometric Analysis of Patient-Reported Outcomes in Breast Cancer Patients Through Item Response Theory

por Schindler, Emilie, Friberg, Lena E., Lum, Bertram L., Wang, Bei, Quartino, Angelica, Li, Chunze, Girish, Sandhya, Jin, Jin Y., Karlsson, Mats O.
Publicado 2018

Prediction of overall survival in patients across solid tumors following atezolizumab treatments: A tumor growth inhibition–overall survival modeling framework

por Chan, Phyllis, Marchand, Mathilde, Yoshida, Kenta, Vadhavkar, Shweta, Wang, Nina, Lin, Alyse, Wu, Benjamin, Ballinger, Marcus, Sternheim, Nitzan, Jin, Jin Y., Bruno, René
Publicado 2021

Modeling Alzheimer's disease progression utilizing clinical trial and ADNI data to predict longitudinal trajectory of CDR‐SB

por Jamalian, Samira, Dolton, Michael, Chanu, Pascal, Ramakrishnan, Vidya, Franco, Yesenia, Wildsmith, Kristin, Manser, Paul, Teng, Edmond, Jin, Jin Y., Quartino, Angelica, Hsu, Joy C.
Publicado 2023

Population pharmacokinetic and exposure–response analysis for trastuzumab administered using a subcutaneous “manual syringe” injection or intravenously in women with HER2-positive...

por Quartino, Angelica L., Hillenbach, Carina, Li, Jing, Li, Hanbin, Wada, Russell D., Visich, Jennifer, Li, Chunze, Heinzmann, Dominik, Jin, Jin Y., Lum, Bert L.
Publicado 2015

Combining “Bottom‐up” and “Top‐down” Approaches to Assess the Impact of Food and Gastric pH on Pictilisib (GDC‐0941) Pharmacokinetics

por Lu, Tong, Fraczkiewicz, Grazyna, Salphati, Laurent, Budha, Nageshwar, Dalziel, Gena, Smelick, Gillian S., Morrissey, Kari M., Davis, John D., Jin, Jin Y., Ware, Joseph A.
Publicado 2017

Pharmacokinetics of polatuzumab vedotin in combination with R/G-CHP in patients with B-cell non-Hodgkin lymphoma

por Shemesh, Colby S., Agarwal, Priya, Lu, Tong, Lee, Calvin, Dere, Randall C., Li, Xiaobin, Li, Chunze, Jin, Jin Y., Girish, Sandhya, Miles, Dale, Lu, Dan
Publicado 2020

Impact of Dose Delays and Alternative Dosing Regimens on Pertuzumab Pharmacokinetics

por Liu, Stephanie N., Lu, Tong, Jin, Jin Y., Li, Chunze, Girish, Sandhya, Melnikov, Fjodor, Badovinac Crnjevic, Tanja, Machackova, Zuzana, Restuccia, Eleonora, Kirschbrown, Whitney P.
Publicado 2021