A Novel NF‐κB Inhibitor, Edasalonexent (CAT‐1004), in Development as a Disease‐Modifying Treatment for Patients With Duchenne Muscular Dystrophy: Phase 1 Safety, Pharmacokinetics,...

por Donovan, Joanne M., Zimmer, Michael, Offman, Elliot, Grant, Toni, Jirousek, Michael
Publicado 2017

CAT‐2003: A novel sterol regulatory element‐binding protein inhibitor that reduces steatohepatitis, plasma lipids, and atherosclerosis in apolipoprotein E*3‐Leiden mice

por Zimmer, Michael, Bista, Pradeep, Benson, Ericka L., Lee, Diana Y., Liu, Feng, Picarella, Dominic, Vega, Rick B., Vu, Chi B., Yeager, Maisy, Ding, Min, Liang, Guosheng, Horton, Jay D., Kleemann, Robert, Kooistra, Teake, Morrison, Martine C., Wielinga, Peter Y., Milne, Jill C., Jirousek, Michael R., Nichols, Andrew J.
Publicado 2017

Small molecule activators of SIRT1 replicate signaling pathways triggered by calorie restriction in vivo

por Smith, Jesse J, Kenney, Renée Deehan, Gagne, David J, Frushour, Brian P, Ladd, William, Galonek, Heidi L, Israelian, Kristine, Song, Jeffrey, Razvadauskaite, Giedre, Lynch, Amy V, Carney, David P, Johnson, Robin J, Lavu, Siva, Iffland, Andre, Elliott, Peter J, Lambert, Philip D, Elliston, Keith O, Jirousek, Michael R, Milne, Jill C, Boss, Olivier
Publicado 2009