Direct Potential Modulation of Neurogenic Differentiation Markers by Granulocyte-Colony Stimulating Factor (G-CSF) in the Rodent Brain

por Kozole, Judith, Heydn, Rosmarie, Wirkert, Eva, Küspert, Sabrina, Aigner, Ludwig, Bruun, Tim-Henrik, Bogdahn, Ulrich, Peters, Sebastian, Johannesen, Siw
Publicado 2022

Value of fluid‐attenuated inversion recovery MRI data analyzed by the lesion segmentation toolbox in amyotrophic lateral sclerosis

por Wirth, Anna M., Johannesen, Siw, Khomenko, Andrei, Baldaranov, Dobri, Bruun, Tim‐Henrik, Wendl, Christina, Schuierer, Gerhard, Greenlee, Mark W., Bogdahn, Ulrich
Publicado 2018

Antisense Oligonucleotide in LNA-Gapmer Design Targeting TGFBR2—A Key Single Gene Target for Safe and Effective Inhibition of TGFβ Signaling

por Kuespert, Sabrina, Heydn, Rosmarie, Peters, Sebastian, Wirkert, Eva, Meyer, Anne-Louise, Siebörger, Mareile, Johannesen, Siw, Aigner, Ludwig, Bogdahn, Ulrich, Bruun, Tim-Henrik
Publicado 2020

Safe and Effective Cynomolgus Monkey GLP—Tox Study with Repetitive Intrathecal Application of a TGFBR2 Targeting LNA-Gapmer Antisense Oligonucleotide as Treatment Candidate for Neu...

por Peters, Sebastian, Wirkert, Eva, Kuespert, Sabrina, Heydn, Rosmarie, Johannesen, Siw, Friedrich, Anita, Mailänder, Susanne, Korte, Sven, Mecklenburg, Lars, Aigner, Ludwig, Bruun, Tim-Henrik, Bogdahn, Ulrich
Publicado 2022

Combinatory Biomarker Use of Cortical Thickness, MUNIX, and ALSFRS-R at Baseline and in Longitudinal Courses of Individual Patients With Amyotrophic Lateral Sclerosis

por Wirth, Anna M., Khomenko, Andrei, Baldaranov, Dobri, Kobor, Ines, Hsam, Ohnmar, Grimm, Thomas, Johannesen, Siw, Bruun, Tim-Henrik, Schulte-Mattler, Wilhelm, Greenlee, Mark W., Bogdahn, Ulrich
Publicado 2018

The TGF-β System As a Potential Pathogenic Player in Disease Modulation of Amyotrophic Lateral Sclerosis

por Peters, Sebastian, Zitzelsperger, Eva, Kuespert, Sabrina, Iberl, Sabine, Heydn, Rosmarie, Johannesen, Siw, Petri, Susanne, Aigner, Ludwig, Thal, Dietmar R., Hermann, Andreas, Weishaupt, Jochen H., Bruun, Tim-Henrik, Bogdahn, Ulrich
Publicado 2017

Biomarker Supervised G-CSF (Filgrastim) Response in ALS Patients

por Johannesen, Siw, Budeus, Bettina, Peters, Sebastian, Iberl, Sabine, Meyer, Anne-Louise, Kammermaier, Tina, Wirkert, Eva, Bruun, Tim-Henrik, Samara, Verena C., Schulte-Mattler, Wilhelm, Herr, Wolfgang, Schneider, Armin, Grassinger, Jochen, Bogdahn, Ulrich
Publicado 2018

Modeling and Bioinformatics Identify Responders to G-CSF in Patients With Amyotrophic Lateral Sclerosis

por Johannesen, Siw, Huie, J. Russell, Budeus, Bettina, Peters, Sebastian, Wirth, Anna M., Iberl, Sabine, Kammermaier, Tina, Kobor, Ines, Wirkert, Eva, Küspert, Sabrina, Tahedl, Marlene, Grassinger, Jochen, Pukrop, Tobias, Schneider, Armin, Aigner, Ludwig, Schulte-Mattler, Wilhelm, Schuierer, Gerhard, Koch, Winfried, Bruun, Tim-Henrik, Ferguson, Adam R., Bogdahn, Ulrich
Publicado 2021

Reconditioning the Neurogenic Niche of Adult Non-human Primates by Antisense Oligonucleotide-Mediated Attenuation of TGFβ Signaling

por Peters, Sebastian, Kuespert, Sabrina, Wirkert, Eva, Heydn, Rosmarie, Jurek, Benjamin, Johannesen, Siw, Hsam, Ohnmar, Korte, Sven, Ludwig, Florian Timo, Mecklenburg, Lars, Mrowetz, Heike, Altendorfer, Barbara, Poupardin, Rodolphe, Petri, Susanne, Thal, Dietmar R., Hermann, Andreas, Weishaupt, Jochen H., Weis, Joachim, Aksoylu, Inci Sevval, Lewandowski, Sebastian A., Aigner, Ludwig, Bruun, Tim-Henrik, Bogdahn, Ulrich
Publicado 2021