Chelator-Based Parameterization of the 12-6-4 Lennard-Jones Molecular Mechanics Potential for More Realistic Metal Ion–Protein Interactions

por Kantakevičius, Paulius, Mathiah, Calvin, Johannissen, Linus O., Hay, Sam
Publicado 2022

Coupled Motions Direct Electrons along Human Microsomal P450 Chains

por Pudney, Christopher R., Khara, Basile, Johannissen, Linus O., Scrutton, Nigel S.
Publicado 2011

Vertebrate Cryptochromes are Vestigial Flavoproteins

por Kutta, Roger J., Archipowa, Nataliya, Johannissen, Linus O., Jones, Alex R., Scrutton, Nigel S.
Publicado 2017

Mechanism of Action of Flavin-Dependent Halogenases

por Barker, Rhys D., Yu, Yuqi, De Maria, Leonardo, Johannissen, Linus O., Scrutton, Nigel S.
Publicado 2022

Decoding Catalysis by Terpene Synthases

por Whitehead, Joshua N., Leferink, Nicole G. H., Johannissen, Linus O., Hay, Sam, Scrutton, Nigel S.
Publicado 2023

C3 and C6 Modification‐Specific OYE Biotransformations of Synthetic Carvones and Sequential BVMO Chemoenzymatic Synthesis of Chiral Caprolactones

por Issa, Issa S., Toogood, Helen S., Johannissen, Linus O., Raftery, James, Scrutton, Nigel S., Gardiner, John M.
Publicado 2019

How Photoactivation Triggers Protochlorophyllide Reduction: Computational Evidence of a Stepwise Hydride Transfer during Chlorophyll Biosynthesis

por Johannissen, Linus O., Taylor, Aoife, Hardman, Samantha J.O., Heyes, Derren J., Scrutton, Nigel S., Hay, Sam
Publicado 2022

A Vitamin B(2)‐Photocatalysed Approach to Methionine Analogues

por Knowles , Oliver J., Johannissen, Linus O., Crisenza, Giacomo E. M., Hay, Sam, Leys, David, Procter, David J.
Publicado 2022

Identification of B cell epitopes enhanced by protein unfolding and aggregation

por Eyes, Timothy J., Austerberry, James I., Dearman, Rebecca J., Johannissen, Linus O., Kimber, Ian, Smith, Noel, Thistlethwaite, Angela, Derrick, Jeremy P.
Publicado 2019

Characterization of the structure and interactions of P450 BM3 using hybrid mass spectrometry approaches

por Jeffreys, Laura N., Pacholarz, Kamila J., Johannissen, Linus O., Girvan, Hazel M., Barran, Perdita E., Voice, Michael W., Munro, Andrew W.
Publicado 2020

Photoinduced Electron Transfer from a 1,4,5,6-Tetrahydro Nicotinamide Adenine Dinucleotide (Phosphate) Analogue to Oxidized Flavin in an Ene-Reductase Flavoenzyme

por Speirs, Magnus, Hardman, Samantha J. O., Iorgu, Andreea I., Johannissen, Linus O., Heyes, Derren J., Scrutton, Nigel S., Sazanovich, Igor V., Hay, Sam
Publicado 2023

Engineering an Efficient and Enantioselective Enzyme for the Morita-Baylis-Hillman Reaction

por Crawshaw, Rebecca, Crossley, Amy E., Johannissen, Linus, Burke, Ashleigh J., Hay, Sam, Levy, Colin, Baker, David, Lovelock, Sarah L., Green, Anthony P.
Publicado 2022

Structural basis of terephthalate recognition by solute binding protein TphC

por Gautom, Trishnamoni, Dheeman, Dharmendra, Levy, Colin, Butterfield, Thomas, Alvarez Gonzalez, Guadalupe, Le Roy, Philip, Caiger, Lewis, Fisher, Karl, Johannissen, Linus, Dixon, Neil
Publicado 2021

Structure and Mechanism of a Viral Collagen Prolyl Hydroxylase

por Longbotham, James E., Levy, Colin, Johannissen, Linus O., Tarhonskaya, Hanna, Jiang, Shuo, Loenarz, Christoph, Flashman, Emily, Hay, Sam, Schofield, Christopher J., Scrutton, Nigel S.
Publicado 2015

Epoxyqueuosine Reductase Structure Suggests a Mechanism for Cobalamin-dependent tRNA Modification

por Payne, Karl A. P., Fisher, Karl, Sjuts, Hanno, Dunstan, Mark S., Bellina, Bruno, Johannissen, Linus, Barran, Perdita, Hay, Sam, Rigby, Stephen E. J., Leys, David
Publicado 2015

Native mass spectrometry reveals the conformational diversity of the UVR8 photoreceptor

por Camacho, Inês S., Theisen, Alina, Johannissen, Linus O., Díaz-Ramos, L. Aranzazú, Christie, John M., Jenkins, Gareth I., Bellina, Bruno, Barran, Perdita, Jones, Alex R.
Publicado 2019

Taming the Reactivity of Monoterpene Synthases To Guide Regioselective Product Hydroxylation

por Leferink, Nicole G. H., Ranaghan, Kara E., Battye, Jaime, Johannissen, Linus O., Hay, Sam, van der Kamp, Marc W., Mulholland, Adrian J., Scrutton, Nigel S.
Publicado 2019

Interplay between chromophore binding and domain assembly by the B(12)-dependent photoreceptor protein, CarH

por Camacho, Inês S., Black, Rachelle, Heyes, Derren J., Johannissen, Linus O., Ramakers, Lennart A. I., Bellina, Bruno, Barran, Perdita E., Hay, Sam, Jones, Alex R.
Publicado 2021

How Is Substrate Halogenation Triggered by the Vanadium Haloperoxidase from Curvularia inaequalis?

por Gérard, Emilie F., Mokkawes, Thirakorn, Johannissen, Linus O., Warwicker, Jim, Spiess, Reynard R., Blanford, Christopher F., Hay, Sam, Heyes, Derren J., de Visser, Sam P.
Publicado 2023

Equatorial Active Site Compaction and Electrostatic Reorganization in Catechol-O-methyltransferase

por Czarnota, Sylwia, Johannissen, Linus O., Baxter, Nicola J., Rummel, Felix, Wilson, Alex L., Cliff, Matthew J., Levy, Colin W., Scrutton, Nigel S., Waltho, Jonathan P., Hay, Sam
Publicado 2019