Inclisiran for the treatment of hypercholesterolaemia: implications and unanswered questions from the ORION trials

por Cupido, Arjen J, Kastelein, John J P
Publicado 2020

Cholesteryl ester transfer protein inhibitors: from high-density lipoprotein cholesterol to low-density lipoprotein cholesterol lowering agents?

por Nurmohamed, Nick S, Ditmarsch, Marc, Kastelein, John J P
Publicado 2021

The effect of CETP inhibitors on new-onset diabetes: a systematic review and meta-analysis

por Dangas, Katerina, Navar, Ann-Marie, Kastelein, John J P
Publicado 2022

Lipid Measures and Cardiovascular Disease Prediction

por van Wijk, Diederik F., Stroes, Erik S. G., Kastelein, John J. P.
Publicado 2009

Transdiagnostic and Disorder-Specific Resting-State Functional Network Alterations in Alcohol Use Disorder, Schizophrenia, Bipolar Affective Disorder and Obsessive-Compulsive Disor...

por Khadse, P. A., Holla, B., G, V., John, J. P., Benegal, V.
Publicado 2023

Delayed Onset, Protracted Delirium and Aspiration Pneumonitis Associated with a Combination of Clozapine and Electroconvulsive Therapy

por Manjunatha, N., Ram Kumar, G. S., Vidyendaran, R., Muralidharan, K., John, J. P.
Publicado 2011

CETP and SGLT2 inhibitor combination therapy improves glycemic control

por Khomtchouk, Bohdan B., Sun, Patrick, Ditmarsch, Marc, Kastelein, John J.P., Davidson, Michael H.
Publicado 2023

Preoperative Transcranial Direct Current Stimulation in Glioma Patients: A Proof of Concept Pilot Study

por Lang, Stefan, Gan, Liu Shi, McLennan, Cael, Kirton, Adam, Monchi, Oury, Kelly, John J. P.
Publicado 2020

Changes in Mipomersen Dosing Regimen Provide Similar Exposure With Improved Tolerability in Randomized Placebo‐Controlled Study of Healthy Volunteers

por Flaim, JoAnn D., Grundy, John S., Baker, Brenda F., McGowan, Mary P., Kastelein, John J. P.
Publicado 2014

Comparison of low-density lipoprotein cholesterol equations in patients with dyslipidaemia receiving cholesterol ester transfer protein inhibition

por Martin, Seth S, Ditmarsch, Marc, Simmons, Mark, Alp, Nicholas, Turner, Traci, Davidson, Michael H, Kastelein, John J P
Publicado 2022

Viscoelastic properties of white and gray matter-derived microglia differentiate upon treatment with lipopolysaccharide but not upon treatment with myelin

por van Wageningen, Thecla A., Antonovaite, Nelda, Paardekam, Erik, Brevé, John J. P., Iannuzzi, Davide, van Dam, Anne-Marie
Publicado 2021

Effects of Supra-Physiological Levothyroxine Dosages on Liver Parameters, Lipids and Lipoproteins in Healthy Volunteers: A Randomized Controlled Crossover Study

por Sjouke, Barbara, Elbers, Laura P. B., van Zaane, Bregje, Kastelein, John J. P., Hovingh, G. Kees, Gerdes, Victor E. A.
Publicado 2017

Tissue transglutaminase in astrocytes is enhanced by inflammatory mediators and is involved in the formation of fibronectin fibril-like structures

por Espitia Pinzón, Nathaly, Brevé, John J. P., Bol, John G. J. M., Drukarch, Benjamin, Baron, Wia, van Dam, Anne-Marie
Publicado 2017

Quality Assessment of the Genetic Test for Familial Hypercholesterolemia in The Netherlands

por Kindt, Iris, Huijgen, Roeland, Boekel, Marieke, van der Gaag, Kristiaan J., Defesche, Joep C., Kastelein, John J. P., de Knijff, Peter
Publicado 2013

Efficacy and Safety of Alirocumab in Patients with Heterozygous Familial Hypercholesterolemia not Adequately Controlled with Current Lipid-Lowering Therapy: Design and Rationale of...

por Kastelein, John J. P., Robinson, Jennifer G., Farnier, Michel, Krempf, Michel, Langslet, Gisle, Lorenzato, Christelle, Gipe, Daniel A., Baccara-Dinet, Marie T.
Publicado 2014

Brain region-specific gene expression profiles in freshly isolated rat microglia

por Doorn, Karlijn J., Brevé, John J. P., Drukarch, Benjamin, Boddeke, Hendrikus W., Huitinga, Inge, Lucassen, Paul J., van Dam, Anne-Marie
Publicado 2015

Safety and efficacy of LY3015014, a monoclonal antibody to proprotein convertase subtilisin/kexin type 9 (PCSK9): a randomized, placebo-controlled Phase 2 study

por Kastelein, John J.P., Nissen, Steven E., Rader, Daniel J., Hovingh, G. Kees, Wang, Ming-Dauh, Shen, Tong, Krueger, Kathryn A.
Publicado 2016

Differential Expression of Tissue Transglutaminase Splice Variants in Peripheral Blood Mononuclear Cells of Primary Progressive Multiple Sclerosis Patients

por Sestito, Claudia, Brevé, John J. P., Killestein, Joep, Teunissen, Charlotte E., Wilhelmus, Micha M. M., Drukarch, Benjamin, van Dam, Anne-Marie
Publicado 2018

Cholesteryl Ester Transfer Protein Inhibition Reduces Major Adverse Cardiovascular Events by Lowering Apolipoprotein B Levels

por Nelson, Adam J., Sniderman, Allan D., Ditmarsch, Marc, Dicklin, Mary R., Nicholls, Stephen J., Davidson, Michael H., Kastelein, John J. P.
Publicado 2022

Two Years after Molecular Diagnosis of Familial Hypercholesterolemia: Majority on Cholesterol-Lowering Treatment but a Minority Reaches Treatment Goal

por Huijgen, Roeland, Kindt, Iris, Verhoeven, Sjoerd B. J., Sijbrands, Eric J. G., Vissers, Maud N., Kastelein, John J. P., Hutten, Barbara A.
Publicado 2010