IFIT1 Exerts Opposing Regulatory Effects on the Inflammatory and Interferon Gene Programs in LPS-Activated Human Macrophages

por John, Sinu P., Sun, Jing, Carlson, Rebecca J., Cao, Binh, Bradfield, Clinton J., Song, Jian, Smelkinson, Margery, Fraser, Iain D.C.
Publicado 2018

Development of a cell system for siRNA screening of pathogen responses in human and mouse macrophages

por Li, Ning, Sun, Jing, Benet, Zachary L., Wang, Ze, Al-Khodor, Souhaila, John, Sinu P., Lin, Bin, Sung, Myong-Hee, Fraser, Iain D. C.
Publicado 2015

Inhibition of Tip60 Reduces Lytic and Latent Gene Expression of Kaposi’s Sarcoma-Associated Herpes Virus (KSHV) and Proliferation of KSHV-Infected Tumor Cells

por Simpson, Sydney, Fiches, Guillaume, Jean, Maxime J., Dieringer, Michael, McGuinness, James, John, Sinu P., Shamay, Meir, Desai, Prashant, Zhu, Jian, Santoso, Netty G.
Publicado 2018

IFITM3 Inhibits Influenza A Virus Infection by Preventing Cytosolic Entry

por Feeley, Eric M., Sims, Jennifer S., John, Sinu P., Chin, Christopher R., Pertel, Thomas, Chen, Li-Mei, Gaiha, Gaurav D., Ryan, Bethany J., Donis, Ruben O., Elledge, Stephen J., Brass, Abraham L.
Publicado 2011

Amphotericin B Increases Influenza A Virus Infection by Preventing IFITM3-Mediated Restriction

por Lin, Tsai-Yu, Chin, Christopher R., Everitt, Aaron R., Clare, Simon, Perreira, Jill M., Savidis, George, Aker, Aaron M., John, Sinu P., Sarlah, David, Carreira, Erick M., Elledge, Stephen J., Kellam, Paul, Brass, Abraham L.
Publicado 2013

Small-molecule screening identifies Syk kinase inhibition and rutaecarpine as modulators of macrophage training and SARS-CoV-2 infection

por John, Sinu P., Singh, Anju, Sun, Jing, Pierre, Makheni Jean, Alsalih, Lulwah, Lipsey, Crystal, Traore, Ziann, Balcom-Luker, Shenavia, Bradfield, Clinton J., Song, Jian, Markowitz, Tovah E., Smelkinson, Margery, Ferrer, Marc, Fraser, Iain D.C.
Publicado 2022

Correction: Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol

por Dorrington, Michael G., Bradfield, Clinton J., Lack, Justin B., Lin, Bin, John, Sinu P., Liang, Jonathan J., Starr, Tregei, Ernst, Orna, Gross, Julia L., Sun, Jing, Miller, Alexandra H., Steele-Mortimer, Olivia, Fraser, Iain D. C.
Publicado 2021

Comprehensive Identification of Host Modulators of HIV-1 Replication using Multiple Orthologous RNAi Reagents

por Zhu, Jian, Davoli, Teresa, Perriera, Jill M., Chin, Christopher R., Gaiha, Gaurav D., John, Sinu P., Sigiollot, Frederic D., Gao, Geng, Xu, Qikai, Qu, Hongjing, Pertel, Thomas, Sims, Jennifer S., Smith, Jennifer A., Baker, Richard E., Maranda, Louise, Ng, Aylwin, Elledge, Stephen J., Brass, Abraham L.
Publicado 2014

IFITM3 restricts the morbidity and mortality associated with influenza

por Everitt, Aaron R., Clare, Simon, Pertel, Thomas, John, Sinu P., Wash, Rachael S., Smith, Sarah E., Chin, Christopher R., Feeley, Eric M., Sims, Jennifer S., Adams, David J., Wise, Helen M., Kane, Leanne, Goulding, David A., Digard, Paul, Anttila, Verneri, Baillie, J. Kenneth, Walsh, Tim S., Hume, David A., Palotie, Aarno, Xue, Yali, Colonna, Vincenza, Tyler-Smith, Chris, Dunning, Jake, Gordon, Stephen B., Smyth, Rosalind L., Openshaw, Peter, Dougan, Gordon, Brass, Abraham L., Kellam, Paul
Publicado 2012