GATA2 deficiency elevates interferon regulatory factor-8 to subvert a progenitor cell differentiation program

por Johnson, Kirby D., Soukup, Alexandra A., Bresnick, Emery H.
Publicado 2022

Master regulatory GATA transcription factors: mechanistic principles and emerging links to hematologic malignancies

por Bresnick, Emery H., Katsumura, Koichi R., Lee, Hsiang-Ying, Johnson, Kirby D., Perkins, Archibald S.
Publicado 2012

Conditionally pathogenic genetic variants of a hematopoietic disease–suppressing enhancer

por Soukup, Alexandra A., Matson, Daniel R., Liu, Peng, Johnson, Kirby D., Bresnick, Emery H.
Publicado 2021

MLG: multilayer graph clustering for multi-condition scRNA-seq data

por Lu, Shan, Conn, Daniel J, Chen, Shuyang, Johnson, Kirby D, Bresnick, Emery H, Keleş, Sündüz
Publicado 2021

RNA-regulatory exosome complex suppresses an apoptotic program to confer erythroid progenitor cell survival in vivo

por Fraga de Andrade, Isabela, Johnson, Kirby D., Mehta, Charu, Dewey, Colin N., Basu, Uttiya, Bresnick, Emery H.
Publicado 2022

Restricting genomic actions of innate immune mediators on fetal hematopoietic progenitor cells

por Tran, Vu L., Liu, Peng, Katsumura, Koichi R., Kim, Erin, Schoff, Bjorn M., Johnson, Kirby D., Bresnick, Emery H.
Publicado 2023

Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo

por Gao, Xin, Johnson, Kirby D., Chang, Yuan-I, Boyer, Meghan E., Dewey, Colin N., Zhang, Jing, Bresnick, Emery H.
Publicado 2013

GATA Factor-G-Protein-Coupled Receptor Circuit Suppresses Hematopoiesis

por Gao, Xin, Wu, Tongyu, Johnson, Kirby D., Lahvic, Jamie L., Ranheim, Erik A., Zon, Leonard I., Bresnick, Emery H.
Publicado 2016

Gata2 +9.5 enhancer regulates adult hematopoietic stem cell self-renewal and T-cell development

por You, Xiaona, Zhou, Yun, Chang, Yuan-I, Kong, Guangyao, Ranheim, Erik A., Johnson, Kirby D., Soukup, Alexandra A., Bresnick, Emery H., Zhang, Jing
Publicado 2022

Cis-regulatory mechanisms governing stem and progenitor cell transitions

por Johnson, Kirby D., Kong, Guangyao, Gao, Xin, Chang, Yuan-I, Hewitt, Kyle J., Sanalkumar, Rajendran, Prathibha, Rajalekshmi, Ranheim, Erik A., Dewey, Colin N., Zhang, Jing, Bresnick, Emery H.
Publicado 2015

Constructing and deconstructing GATA2-regulated cell fate programs to establish developmental trajectories

por Johnson, Kirby D., Conn, Daniel J., Shishkova, Evgenia, Katsumura, Koichi R., Liu, Peng, Shen, Siqi, Ranheim, Erik A., Kraus, Sean G., Wang, Weixin, Calvo, Katherine R., Hsu, Amy P., Holland, Steven M., Coon, Joshua J., Keles, Sunduz, Bresnick, Emery H.
Publicado 2020

Pathogenic human variant that dislocates GATA2 zinc fingers disrupts hematopoietic gene expression and signaling networks

por Jung, Mabel Minji, Shen, Siqi, Botten, Giovanni A., Olender, Thomas, Katsumura, Koichi R., Johnson, Kirby D., Soukup, Alexandra A., Liu, Peng, Zhang, Qingzhou, Jensvold, Zena D., Lewis, Peter W., Beagrie, Robert A., Low, Jason K.K., Yang, Lihua, Mackay, Joel P., Godley, Lucy A., Brand, Marjorie, Xu, Jian, Keles, Sunduz, Bresnick, Emery H.
Publicado 2023