Wild Type Mesenchymal Cells Contribute to the Lung Pathology of Lymphangioleiomyomatosis

por Clements, Debbie, Dongre, Arundhati, Krymskaya, Vera P., Johnson, Simon R.
Publicado 2015

Extra-Cellular Matrix Proteins Induce Matrix Metalloproteinase-1 (MMP-1) Activity and Increase Airway Smooth Muscle Contraction in Asthma

por Rogers, Natasha K., Clements, Debbie, Dongre, Arundhati, Harrison, Tim W., Shaw, Dominic, Johnson, Simon R.
Publicado 2014

Evolution of lung pathology in lymphangioleiomyomatosis: associations with disease course and treatment response

por Miller, Suzanne, Stewart, Iain D, Clements, Debbie, Soomro, Irshad, Babaei‐Jadidi, Roya, Johnson, Simon R
Publicado 2020

Clinical utility of diagnostic guidelines and putative biomarkers in lymphangioleiomyomatosis

por Chang, William YC, Cane, Jennifer L, Blakey, John D, Kumaran, Maruti, Pointon, Kate S, Johnson, Simon R
Publicado 2012

Natural history of angiomyolipoma in lymphangioleiomyomatosis: implications for screening and surveillance

por Yeoh, Zhao W, Navaratnam, Vidya, Bhatt, Rupesh, McCafferty, Ian, Hubbard, Richard B, Johnson, Simon R
Publicado 2014

A theoretical model of inflammation- and mechanotransduction-driven asthmatic airway remodelling

por Hill, Michael R., Philp, Christopher J., Billington, Charlotte K., Tatler, Amanda L., Johnson, Simon R., O’Dea, Reuben D., Brook, Bindi S.
Publicado 2018

Elevated PLAUR is observed in the airway epithelium of asthma patients and blocking improves barrier integrity

por Portelli, Michael A., Bhaker, Sangita, Pang, Vincent, Bates, David O., Johnson, Simon R., Mazar, Andrew P., Shaw, Dominick, Brightling, Christopher, Sayers, Ian
Publicado 2023

Secretory leukocyte protease inhibitor gene deletion alters bleomycin-induced lung injury, but not development of pulmonary fibrosis

por Habgood, Anthony N, Tatler, Amanda L, Porte, Joanne, Wahl, Sharon M, Laurent, Geoffrey J, John, Alison E, Johnson, Simon R, Jenkins, Gisli
Publicado 2016

Air travel and incidence of pneumothorax in lymphangioleiomyomatosis

por Gonano, Cynthia, Pasquier, Jérôme, Daccord, Cécile, Johnson, Simon R., Harari, Sergio, Leclerc, Violette, Falconer, Lucy, Miano, Eleonora, Cordier, Jean-François, Cottin, Vincent, Lazor, Romain
Publicado 2018

Accelerated extracellular matrix turnover during exacerbations of COPD

por Sand, Jannie M. B., Knox, Alan J., Lange, Peter, Sun, Shu, Kristensen, Jacob H., Leeming, Diana J., Karsdal, Morten A., Bolton, Charlotte E., Johnson, Simon R.
Publicado 2015

Airway epithelial cell isolation techniques affect DNA methylation profiles with consequences for analysis of asthma related perturbations to DNA methylation

por Clifford, Rachel L., Patel, Jamie, MacIsaac, Julia L., McEwen, Lisa M., Johnson, Simon R., Shaw, Dominick, Knox, Alan J., Hackett, Tillie-Louise, Kobor, Michael S.
Publicado 2019

The vitamin D binding protein axis modifies disease severity in lymphangioleiomyomatosis

por Miller, Suzanne, Coveney, Clare, Johnson, Janice, Farmaki, Aliki-Eleni, Gupta, Nishant, Tobin, Martin D., Wain, Louise V., McCormack, Francis X., Boocock, David J., Johnson, Simon R.
Publicado 2018

The Role of Inflammation Resolution Speed in Airway Smooth Muscle Mass Accumulation in Asthma: Insight from a Theoretical Model

por Chernyavsky, Igor L., Croisier, Huguette, Chapman, Lloyd A. C., Kimpton, Laura S., Hiorns, Jonathan E., Brook, Bindi S., Jensen, Oliver E., Billington, Charlotte K., Hall, Ian P., Johnson, Simon R.
Publicado 2014

Accelerated (19)F·MRI Detection of Matrix Metalloproteinase-2/-9 through Responsive Deactivation of Paramagnetic Relaxation Enhancement

por Faas, Henryk M., Krupa, James L., Taylor, Alexander J., Zamberlan, Francesco, Philp, Christopher J., Williams, Huw E. L., Johnson, Simon R., Pavlovskaya, Galina E., Thomas, Neil R., Meersmann, Thomas
Publicado 2019

COVID-19 in Lymphangioleiomyomatosis: An International Study of Outcomes and Impact of Mechanistic Target of Rapamycin Inhibition

por Baldi, Bruno Guedes, Radzikowska, Elzbieta, Cottin, Vincent, Dilling, Daniel F., Ataya, Ali, Carvalho, Carlos Roberto Ribeiro, Harari, Sergio, Koslow, Matthew, Grutters, Jan C., Inoue, Yoshikazu, Gupta, Nishant, Johnson, Simon R.
Publicado 2022

Cardiovascular and inflammatory effects of simvastatin therapy in patients with COPD: a randomized controlled trial

por John, Michelle E, Cockcroft, John R, McKeever, Tricia M, Coward, William R, Shale, Dennis J, Johnson, Simon R, Thornton, Jim G, Harrison, Timothy W, Knox, Alan J, Bolton, Charlotte E
Publicado 2015

Lysyl oxidase like 2 is increased in asthma and contributes to asthmatic airway remodelling

por Ramis, Jopeth, Middlewick, Robert, Pappalardo, Francesco, Cairns, Jennifer T., Stewart, Iain D., John, Alison E., Naveed, Shams-Un-Nisa, Krishnan, Ramaswamy, Miller, Suzanne, Shaw, Dominick E., Brightling, Christopher E., Buttery, Lee, Rose, Felicity, Jenkins, Gisli, Johnson, Simon R., Tatler, Amanda L.
Publicado 2022

Association of MMP - 12 polymorphisms with severe and very severe COPD: A case control study of MMPs - 1, 9 and 12 in a European population

por Haq, Imran, Chappell, Sally, Johnson, Simon R, Lotya, Juzer, Daly, Leslie, Morgan, Kevin, Guetta-Baranes, Tamar, Roca, Josep, Rabinovich, Roberto, Millar, Ann B, Donnelly, Seamas C, Keatings, Vera, MacNee, William, Stolk, Jan, Hiemstra, Pieter S, Miniati, Massimo, Monti, Simonetta, O'Connor, Clare M, Kalsheker, Noor
Publicado 2010

A lung targeted miR-29 mimic as a therapy for pulmonary fibrosis

por Chioccioli, Maurizio, Roy, Subhadeep, Newell, Rachel, Pestano, Linda, Dickinson, Brent, Rigby, Kevin, Herazo-Maya, Jose, Jenkins, Gisli, Ian, Steward, Saini, Gauri, Johnson, Simon R., Braybrooke, Rebecca, Yu, Guying, Sauler, Maor, Ahangari, Farida, Ding, Shuizi, DeIuliis, Joseph, Aurelien, Nachelle, Montgomery, Rusty L., Kaminski, Naftali
Publicado 2022

Tuberous Sclerosis Complex (TSC): Expert Recommendations for Provision of Coordinated Care

por Annear, Nicholas M. P., Appleton, Richard E., Bassi, Zahabiyah, Bhatt, Rupesh, Bolton, Patrick F., Crawford, Pamela, Crowe, Alex, Tossi, Maureen, Elmslie, Frances, Finlay, Eric, Gale, Daniel P., Henderson, Alex, Jones, Elizabeth A., Johnson, Simon R., Joss, Shelagh, Kerecuk, Larissa, Lipkin, Graham, Morrison, Patrick J., O'Callaghan, Finbar J., Cadwgan, Jill, Ong, Albert C. M., Sampson, Julian R., Shepherd, Charles, Kingswood, J. Chris
Publicado 2019