Development and application of a pediatric mechanistic kidney model

por Salem, Farzaneh, Small, Ben G., Johnson, Trevor N.
Publicado 2022

Physiologically Based Pharmacokinetics Modeling in the Neonatal Population—Current Advances, Challenges, and Opportunities

por Dinh, Jean, Johnson, Trevor N., Grimstein, Manuela, Lewis, Tamorah
Publicado 2023

Increasing application of pediatric physiologically based pharmacokinetic models across academic and industry organizations

por Johnson, Trevor N., Small, Ben G., Rowland Yeo, Karen
Publicado 2022

Physiologically Based Pharmacokinetic Modelling to Predict Imatinib Exposures in Cancer Patients with Renal Dysfunction: A Case Study

por Rowland Yeo, Karen, Hatley, Oliver, Small, Ben G., Johnson, Trevor N.
Publicado 2023

A best practice framework for applying physiologically‐based pharmacokinetic modeling to pediatric drug development

por Johnson, Trevor N., Small, Ben G., Berglund, Eva Gil, Rowland Yeo, Karen
Publicado 2021

Using a Vancomycin PBPK Model in Special Populations to Elucidate Case‐Based Clinical PK Observations

por Emoto, Chie, Johnson, Trevor N., McPhail, Brooks T., Vinks, Alexander A., Fukuda, Tsuyoshi
Publicado 2018

PBPK Model of Morphine Incorporating Developmental Changes in Hepatic OCT1 and UGT2B7 Proteins to Explain the Variability in Clearances in Neonates and Small Infants

por Emoto, Chie, Johnson, Trevor N., Neuhoff, Sibylle, Hahn, David, Vinks, Alexander A., Fukuda, Tsuyoshi
Publicado 2018

Does “Birth” as an Event Impact Maturation Trajectory of Renal Clearance via Glomerular Filtration? Reexamining Data in Preterm and Full‐Term Neonates by Avoiding the Creatinine Bi...

por Salem, Farzaneh, Johnson, Trevor N., Hodgkinson, Arran B. J., Ogungbenro, Kayode, Rostami‐Hodjegan, Amin
Publicado 2020

Does age affect gastric emptying time? A model‐based meta‐analysis of data from premature neonates through to adults

por Bonner, Jennifer J., Vajjah, Pavan, Abduljalil, Khaled, Jamei, Masoud, Rostami‐Hodjegan, Amin, Tucker, Geoffrey T., Johnson, Trevor N.
Publicado 2015

A Theoretical Physiologically‐Based Pharmacokinetic Approach to Ascertain Covariates Explaining the Large Interpatient Variability in Tacrolimus Disposition

por Emoto, Chie, Johnson, Trevor N., Hahn, David, Christians, Uwe, Alloway, Rita R., Vinks, Alexander A., Fukuda, Tsuyoshi
Publicado 2019

The Short Grit Scale (GRIT-S) Does Not Relate to Acute Muscular Endurance Performance

por Haischer, Michael H., Cooke, Daniel M., Carzoli, Joseph P., Johnson, Trevor K., Shipherd, Amber M., Zourdos, Michael C.
Publicado 2021

Aurora B couples chromosome alignment with anaphase by targeting BubR1, Mad2, and Cenp-E to kinetochores

por Ditchfield, Claire, Johnson, Victoria L., Tighe, Anthony, Ellston, Rebecca, Haworth, Carolyn, Johnson, Trevor, Mortlock, Andrew, Keen, Nicholas, Taylor, Stephen S.
Publicado 2003

Development of a physiologically based pharmacokinetic model of actinomycin D in children with cancer

por Walsh, Christopher, Bonner, Jennifer J., Johnson, Trevor N., Neuhoff, Sibylle, Ghazaly, Essam A., Gribben, John G., Boddy, Alan V., Veal, Gareth J.
Publicado 2016

Insights in the maturational processes influencing hydrocortisone pharmacokinetics in congenital adrenal hyperplasia patients using a middle-out approach

por Michelet, Robin, Bindellini, Davide, Melin, Johanna, Neumann, Uta, Blankenstein, Oliver, Huisinga, Wilhelm, Johnson, Trevor N., Whitaker, Martin J., Ross, Richard, Kloft, Charlotte
Publicado 2023

Can Population Modelling Principles be Used to Identify Key PBPK Parameters for Paediatric Clearance Predictions? An Innovative Application of Optimal Design Theory

por Calvier, Elisa A. M., Nguyen, Thu Thuy, Johnson, Trevor N., Rostami-Hodjegan, Amin, Tibboel, Dick, Krekels, Elke H. J., Knibbe, Catherijne A. J.
Publicado 2018

Hippocampal Growth Factor and Myokine Cathepsin B Expression following Aerobic and Resistance Training in 3xTg-AD Mice

por Pena, Gabriel S., Paez, Hector G., Johnson, Trevor K., Halle, Jessica L., Carzoli, Joseph P., Visavadiya, Nishant P., Zourdos, Michael C., Whitehurst, Michael A., Khamoui, Andy V.
Publicado 2020

Are body surface area based estimates of liver volume applicable to children with overweight or obesity? An in vivo validation study

por Hosey‐Cojocari, Chelsea, Chan, Sherwin S., Friesen, Chance S., Robinson, Amie, Williams, Veronica, Swanson, Erica, O’Toole, Daniel, Radford, Jansynn, Mardis, Neil, Johnson, Trevor N., Leeder, J. Steven, Shakhnovich, Valentina
Publicado 2021

Chloroquine Dosing Recommendations for Pediatric COVID‐19 Supported by Modeling and Simulation

por Verscheijden, Laurens F. M., van der Zanden, Tjitske M., van Bussel, Lianne P. M., de Hoop‐Sommen, Marika, Russel, Frans G. M., Johnson, Trevor N., de Wildt, Saskia N.
Publicado 2020

RPE vs. Percentage 1RM Loading in Periodized Programs Matched for Sets and Repetitions

por Helms, Eric R., Byrnes, Ryan K., Cooke, Daniel M., Haischer, Michael H., Carzoli, Joseph P., Johnson, Trevor K., Cross, Matthew R., Cronin, John B., Storey, Adam G., Zourdos, Michael C.
Publicado 2018

Pediatric Pharmacokinetics and Dose Predictions: A Report of a Satellite Meeting to the 10th Juvenile Toxicity Symposium

por van Groen, Bianca D., Pilla Reddy, Venkatesh, Badée, Justine, Olivares‐Morales, Andrés, Johnson, Trevor N., Nicolaï, Johan, Annaert, Pieter, Smits, Anne, de Wildt, Saskia N., Knibbe, Catherijne A. J., de Zwart, Loeckie
Publicado 2020