Dry Powder and Nebulized Aerosol Inhalation of Pharmaceuticals Delivered to Mice Using a Nose-only Exposure System

por Phillips, Jonathan E., Zhang, Xuxia, Johnston, James A.
Publicado 2017

The DUB/USP17 deubiquitinating enzymes: A gene family within a tandemly repeated sequence, is also embedded within the copy number variable Beta-defensin cluster

por Burrows, James F, Scott, Christopher J, Johnston, James A
Publicado 2010

A Novel High-Throughput Technique for Identifying Monoclonal Antibodies Capable of Death Receptor Induced Apoptosis

por Kwok, Hang Fai, Gormley, Julie A., Scott, Christopher J., Johnston, James A., Olwill, Shane A.
Publicado 2009

A Role of Suppressor of Cytokine Signaling 3 (SOCS3/CIS3/SSI3) in CD28-mediated Interleukin 2 Production

por Matsumoto, Akira, Seki, Yoh-ichi, Watanabe, Ryosuke, Hayashi, Katsuhiko, Johnston, James A., Harada, Yohsuke, Abe, Ryo, Yoshimura, Akihiko, Kubo, Masato
Publicado 2003

The deubiquitinating enzyme USP17 is associated with nonsmall cell lung cancer (NSCLC) recurrence and metastasis

por McFarlane, Cheryl, McFarlane, Suzanne, Paul, Ian, Arthur, Kenneth, Scheaff, Michael, Kerr, Keith, Stevenson, Michael, Fennell, Dean A., Johnston, James A.
Publicado 2013

A conditional form of Bruton's tyrosine kinase is sufficient to activate multiple downstream signaling pathways via PLC Gamma 2 in B cells

por Tomlinson, Michael G, Woods, Douglas B, McMahon, Martin, Wahl, Matthew I, Witte, Owen N, Kurosaki, Tomohiro, Bolen, Joseph B, Johnston, James A
Publicado 2001

A nanoparticle vaccine that targets neoantigen peptides to lymphoid tissues elicits robust antitumor T cell responses

por Arbelaez, Carlos A., Estrada, Juan, Gessner, Melissa A., Glaus, Charles, Morales, Agnieszka B., Mohn, Deanna, Phee, Hyewon, Lipford, J. Russell, Johnston, James A.
Publicado 2020

Btk Regulates Macrophage Polarization in Response to Lipopolysaccharide

por Ní Gabhann, Joan, Hams, Emily, Smith, Siobhán, Wynne, Claire, Byrne, Jennifer C., Brennan, Kiva, Spence, Shaun, Kissenpfennig, Adrien, Johnston, James A., Fallon, Padraic G., Jefferies, Caroline A.
Publicado 2014

Antibody Targeting of Cathepsin S Inhibits Angiogenesis and Synergistically Enhances Anti-VEGF

por Ward, Claire, Kuehn, Diana, Burden, Roberta E., Gormley, Julie A., Jaquin, Thomas J., Gazdoiu, Mihaela, Small, Donna, Bicknell, Roy, Johnston, James A., Scott, Christopher J., Olwill, Shane A.
Publicado 2010

USP17 is required for clathrin mediated endocytosis of epidermal growth factor receptor

por Jaworski, Jakub, de la Vega, Michelle, Fletcher, Sarah J., McFarlane, Cheryl, Greene, Michelle K., Smyth, Andrew W., Van Schaeybroeck, Sandra, Johnston, James A., Scott, Christopher J., Rappoport, Joshua Z., Burrows, James F.
Publicado 2014

The deubiquitinating enzyme USP17 is essential for GTPase subcellular localization and cell motility

por de la Vega, Michelle, Kelvin, Alyson A., Dunican, Dara J., McFarlane, Cheryl, Burrows, James F., Jaworski, Jakub, Stevenson, Nigel J., Dib, Karim, Rappoport, Joshua Z., Scott, Christopher J., Long, Aideen, Johnston, James A.
Publicado 2011

Quantitative measurement of the requirement of diverse protein degradation pathways in MHC class I peptide presentation

por Mamrosh, Jennifer L., Sherman, David J., Cohen, Joseph R., Johnston, James A., Joubert, Marisa K., Li, Jing, Lipford, J. Russell, Lomenick, Brett, Moradian, Annie, Prabhu, Siddharth, Sweredoski, Michael J., Vander Lugt, Bryan, Verma, Rati, Deshaies, Raymond J.
Publicado 2023

Differing roles for short chain fatty acids and GPR43 agonism in the regulation of intestinal barrier function and immune responses

por D’Souza, Warren N., Douangpanya, Jason, Mu, Sharon, Jaeckel, Peter, Zhang, Ming, Maxwell, Joseph R., Rottman, James B., Labitzke, Katja, Willee, Angela, Beckmann, Holger, Wang, Yingcai, Li, Yang, Schwandner, Ralf, Johnston, James A., Towne, Jennifer E., Hsu, Hailing
Publicado 2017

SOCS2 regulates T helper type 2 differentiation and the generation of type 2 allergic responses

por Knosp, Camille A., Carroll, Helen P., Elliott, Joanne, Saunders, Sean P., Nel, Hendrik J., Amu, Sylvie, Pratt, Joanne C., Spence, Shaun, Doran, Emma, Cooke, Nicola, Jackson, Ruaidhri, Swift, Jonathan, Fitzgerald, Denise C., Heaney, Liam G., Fallon, Padraic G., Kissenpfennig, Adrien, Johnston, James A.
Publicado 2011

Antibody targeting of Cathepsin S induces antibody-dependent cellular cytotoxicity

por Kwok, Hang Fai, Buick, Richard J, Kuehn, Diana, Gormley, Julie A, Doherty, Declan, Jaquin, Thomas J, McClurg, Angela, Ward, Claire, Byrne, Teresa, Jaworski, Jacob, Leung, Ka Lai, Snoddy, Philip, McAnally, Christine, Burden, Roberta E, Gray, Breena, Lowry, Jenny, Sermadiras, Isabelle, Gruszka, Natalia, Courtenay-Luck, Nigel, Kissenpfennig, Adrien, Scott, Christopher J, Johnston, James A, Olwill, Shane A
Publicado 2011

Drug Repurposing: The Anthelmintics Niclosamide and Nitazoxanide Are Potent TMEM16A Antagonists That Fully Bronchodilate Airways

por Miner, Kent, Labitzke, Katja, Liu, Benxian, Wang, Paul, Henckels, Kathryn, Gaida, Kevin, Elliott, Robin, Chen, Jian Jeffrey, Liu, Longbin, Leith, Anh, Trueblood, Esther, Hensley, Kelly, Xia, Xing-Zhong, Homann, Oliver, Bennett, Brian, Fiorino, Mike, Whoriskey, John, Yu, Gang, Escobar, Sabine, Wong, Min, Born, Teresa L., Budelsky, Alison, Comeau, Mike, Smith, Dirk, Phillips, Jonathan, Johnston, James A., McGivern, Joseph G., Weikl, Kerstin, Powers, David, Kunzelmann, Karl, Mohn, Deanna, Hochheimer, Andreas, Sullivan, John K.
Publicado 2019

A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma

por Smith, Dirk, Helgason, Hannes, Sulem, Patrick, Bjornsdottir, Unnur Steina, Lim, Ai Ching, Sveinbjornsson, Gardar, Hasegawa, Haruki, Brown, Michael, Ketchem, Randal R., Gavala, Monica, Garrett, Logan, Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Sigurdsson, Asgeir, Magnusson, Olafur T., Eyjolfsson, Gudmundur I., Olafsson, Isleifur, Onundarson, Pall Torfi, Sigurdardottir, Olof, Gislason, David, Gislason, Thorarinn, Ludviksson, Bjorn Runar, Ludviksdottir, Dora, Boezen, H. Marike, Heinzmann, Andrea, Krueger, Marcus, Porsbjerg, Celeste, Ahluwalia, Tarunveer S., Waage, Johannes, Backer, Vibeke, Deichmann, Klaus A., Koppelman, Gerard H., Bønnelykke, Klaus, Bisgaard, Hans, Masson, Gisli, Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F., Johnston, James A., Jonsdottir, Ingileif, Stefansson, Kari
Publicado 2017