Synthetic vaccine particles for durable cytolytic T lymphocyte responses and anti-tumor immunotherapy

por Ilyinskii, Petr O., Kovalev, Grigoriy I., O’Neil, Conlin P., Roy, Christopher J., Michaud, Alicia M., Drefs, Natalia M., Pechenkin, Mikhail A., Fu, Fen-ni, Johnston, Lloyd P. M., Ovchinnikov, Dmitry A., Kishimoto, Takashi Kei
Publicado 2018

ImmTOR nanoparticles enhance AAV transgene expression after initial and repeat dosing in a mouse model of methylmalonic acidemia

por Ilyinskii, Petr O., Michaud, Alicia M., Rizzo, Gina L., Roy, Christopher J., Leung, Sheldon S., Elkins, Stephanie L., Capela, Teresa, Chowdhury, Aparajita, Li, Lina, Chandler, Randy J., Manoli, Irini, Andres-Mateos, Eva, Johnston, Lloyd P.M., Vandenberghe, Luk H., Venditti, Charles P., Kishimoto, Takashi Kei
Publicado 2021

Adjuvant-carrying synthetic vaccine particles augment the immune response to encapsulated antigen and exhibit strong local immune activation without inducing systemic cytokine rele...

por Ilyinskii, Petr O., Roy, Christopher J., O’Neil, Conlin P., Browning, Erica A., Pittet, Lynnelle A., Altreuter, David H., Alexis, Frank, Tonti, Elena, Shi, Jinjun, Basto, Pamela A., Iannacone, Matteo, Radovic-Moreno, Aleksandar F., Langer, Robert S., Farokhzad, Omid C., von Andrian, Ulrich H., Johnston, Lloyd P.M., Kishimoto, Takashi Kei
Publicado 2014