Effects of Excipients on the Structure and Dynamics of Filgrastim Monitored by Thermal Unfolding Studies by CD and NMR Spectroscopy

por Ghasriani, Houman, Frahm, Grant E., Johnston, Michael J. W., Aubin, Yves
Publicado 2020

Evaluation of Microflow Digital Imaging Particle Analysis for Sub-Visible Particles Formulated with an Opaque Vaccine Adjuvant

por Frahm, Grant E., Pochopsky, Alex W. T., Clarke, Tessa M., Johnston, Michael J. W.
Publicado 2016

Determination of Supplier-to-Supplier and Lot-to-Lot Variability in Glycation of Recombinant Human Serum Albumin Expressed in Oryza sativa

por Frahm, Grant E., Smith, Daryl G. S., Kane, Anita, Lorbetskie, Barry, Cyr, Terry D., Girard, Michel, Johnston, Michael J. W.
Publicado 2014

Data set for mass spectrometric analysis of recombinant human serum albumin from various expression systems

por Smith, Daryl G.S., Frahm, Grant E., Kane, Anita, Lorbetskie, Barry, Girard, Michel, Johnston, Michael J.W., Cyr, Terry D.
Publicado 2015

Influence of bound dodecanoic acid on the reconstitution of albumin nanoparticles from a lyophilized state

por Luebbert, Christian C. E., Mansa, Rola, Rahman, Raisa, Jakubek, Zygmunt J., Frahm, Grant E., Zou, Shan, Johnston, Michael J. W.
Publicado 2021

Nanoparticle size and production efficiency are affected by the presence of fatty acids during albumin nanoparticle fabrication

por Luebbert, Christian C., Clarke, Tessa M., Pointet, Roberta, Frahm, Grant E., Tam, Sharon, Lorbetskie, Barry, Sauvé, Simon, Johnston, Michael J. W.
Publicado 2017

Strategies for the production of isotopically labelled Fab fragments of therapeutic antibodies in Komagataella phaffii (Pichia pastoris) and Escherichia coli for NMR studies

por Gagné, Donald, Sarker, Muzaddid, Gingras, Geneviève, Hodgson, Derek J., Frahm, Grant, Creskey, Marybeth, Lorbetskie, Barry, Bigelow, Stewart, Wang, Jun, Zhang, Xu, Johnston, Michael J. W., Lu, Huixin, Aubin, Yves
Publicado 2023

The Expression Kinetics and Immunogenicity of Lipid Nanoparticles Delivering Plasmid DNA and mRNA in Mice

por Zhang, Wanyue, Pfeifle, Annabelle, Lansdell, Casey, Frahm, Grant, Cecillon, Jonathon, Tamming, Levi, Gravel, Caroline, Gao, Jun, Thulasi Raman, Sathya N., Wang, Lisheng, Sauve, Simon, Rosu-Myles, Michael, Li, Xuguang, Johnston, Michael J. W.
Publicado 2023

A comprehensive proteomics profiling identifies NRP1 as a novel identity marker of human bone marrow mesenchymal stromal cell-derived small extracellular vesicles

por Munshi, Afnan, Mehic, Jelica, Creskey, Marybeth, Gobin, Jonathan, Gao, Jun, Rigg, Emma, Muradia, Gauri, Luebbert, Christian C., Westwood, Carole, Stalker, Andrew, Allan, David S., Johnston, Michael J. W., Cyr, Terry, Rosu-Myles, Michael, Lavoie, Jessie R.
Publicado 2019

Hollow-fiber bioreactor production of extracellular vesicles from human bone marrow mesenchymal stromal cells yields nanovesicles that mirrors the immuno-modulatory antigenic signa...

por Gobin, Jonathan, Muradia, Gauri, Mehic, Jelica, Westwood, Carole, Couvrette, Lauren, Stalker, Andrew, Bigelow, Stewart, Luebbert, Christian C., Bissonnette, Frédéric St-Denis, Johnston, Michael J. W., Sauvé, Simon, Tam, Roger Y., Wang, Lisheng, Rosu-Myles, Michael, Lavoie, Jessie R.
Publicado 2021

DNA lipid nanoparticle vaccine targeting outer surface protein C affords protection against homologous Borrelia burgdorferi needle challenge in mice

por Pfeifle, Annabelle, Thulasi Raman, Sathya N., Lansdell, Casey, Zhang, Wanyue, Tamming, Levi, Cecillon, Jonathon, Laryea, Emmanuel, Patel, Devina, Wu, Jianguo, Gravel, Caroline, Frahm, Grant, Gao, Jun, Chen, Wangxue, Chaconas, George, Sauve, Simon, Rosu-Myles, Michael, Wang, Lisheng, Johnston, Michael J. W., Li, Xuguang
Publicado 2023

Bivalent vaccines effectively protect mice against influenza A and respiratory syncytial viruses

por Raman, Sathya N. Thulasi, Zetner, Adrian, Hashem, Anwar M., Patel, Devina, Wu, Jianguo, Gravel, Caroline, Gao, Jun, Zhang, Wanyue, Pfeifle, Annabelle, Tamming, Levi, Parikh, Karan, Cao, Jingxin, Tam, Roger, Safronetz, David, Chen, Wangxue, Johnston, Michael J.W., Wang, Lisheng, Sauve, Simon, Rosu-Myles, Michael, Domselaar, Gary Van, Li, Xuguang
Publicado 2023

DNA Based Vaccine Expressing SARS-CoV-2 Spike-CD40L Fusion Protein Confers Protection Against Challenge in a Syrian Hamster Model

por Tamming, Levi A., Duque, Diana, Tran, Anh, Zhang, Wanyue, Pfeifle, Annabelle, Laryea, Emmanuel, Wu, Jianguo, Raman, Sathya N. Thulasi, Gravel, Caroline, Russell, Marsha S., Hashem, Anwar M., Alsulaiman, Reem M., Alhabbab, Rowa Y., Gao, Jun, Safronetz, David, Cao, Jingxin, Wang, Lisheng, Chen, Wangxue, Johnston, Michael J. W., Sauve, Simon, Rosu-Myles, Michael, Li, Xuguang
Publicado 2022