The Human Fungal Pathogen Cryptococcus neoformans Escapes Macrophages by a Phagosome Emptying Mechanism That Is Inhibited by Arp2/3 Complex-Mediated Actin Polymerisation

por Johnston, Simon A., May, Robin C.
Publicado 2010

Immunity to Cryptococcus neoformans and C. gattii during cryptococcosis

por Gibson, Josie F., Johnston, Simon A.
Publicado 2015

PPAR-gamma Fun(gi) With Prostaglandin

por Evans, Robert J., Johnston, Simon A.
Publicado 2020

Cryptococcus neoformans Thermotolerance to Avian Body Temperature Is Sufficient For Extracellular Growth But Not Intracellular Survival In Macrophages

por Johnston, Simon A., Voelz, Kerstin, May, Robin C.
Publicado 2016

Nutritional Requirements and Their Importance for Virulence of Pathogenic Cryptococcus Species

por Watkins, Rhys A., King, Jason S., Johnston, Simon A.
Publicado 2017

Automated Analysis of Cryptococcal Macrophage Parasitism Using GFP-Tagged Cryptococci

por Voelz, Kerstin, Johnston, Simon A., Rutherford, Julian C., May, Robin C.
Publicado 2010

Cryptococcus neoformans Escape From Dictyostelium Amoeba by Both WASH-Mediated Constitutive Exocytosis and Vomocytosis

por Watkins, Rhys A., Andrews, Alexandre, Wynn, Charlotte, Barisch, Caroline, King, Jason S., Johnston, Simon A.
Publicado 2018

Arp2/3 complex activity in filopodia of spreading cells

por Johnston, Simon A, Bramble, Jonathan P, Yeung, Chun L, Mendes, Paula M, Machesky, Laura M
Publicado 2008

‘Division of labour’ in response to host oxidative burst drives a fatal Cryptococcus gattii outbreak

por Voelz, Kerstin, Johnston, Simon A., Smith, Leanne M., Hall, Rebecca A., Idnurm, Alexander, May, Robin C.
Publicado 2014

Microevolutionary traits and comparative population genomics of the emerging pathogenic fungus Cryptococcus gattii

por Farrer, Rhys A., Voelz, Kerstin, Henk, Daniel A., Johnston, Simon A., Fisher, Matthew C., May, Robin C., Cuomo, Christina A.
Publicado 2016

Inhibition of Classical and Alternative Modes of Respiration in Candida albicans Leads to Cell Wall Remodeling and Increased Macrophage Recognition

por Duvenage, Lucian, Walker, Louise A., Bojarczuk, Aleksandra, Johnston, Simon A., MacCallum, Donna M., Munro, Carol A., Gourlay, Campbell W.
Publicado 2019

Actin polymerization driven by WASH causes V-ATPase retrieval and vesicle neutralization before exocytosis

por Carnell, Michael, Zech, Tobias, Calaminus, Simon D., Ura, Seiji, Hagedorn, Monica, Johnston, Simon A., May, Robin C., Soldati, Thierry, Machesky, Laura M., Insall, Robert H.
Publicado 2011

CD4-Transgenic Zebrafish Reveal Tissue-Resident Th2- and Regulatory T Cell–like Populations and Diverse Mononuclear Phagocytes

por Dee, Christopher T., Nagaraju, Raghavendar T., Athanasiadis, Emmanouil I., Gray, Caroline, Fernandez del Ama, Laura, Johnston, Simon A., Secombes, Christopher J., Cvejic, Ana, Hurlstone, Adam F. L.
Publicado 2016

The autophagic response to Staphylococcus aureus provides an intracellular niche in neutrophils

por Prajsnar, Tomasz K., Serba, Justyna J., Dekker, Bernice M., Gibson, Josie F., Masud, Samrah, Fleming, Angeleen, Johnston, Simon A., Renshaw, Stephen A., Meijer, Annemarie H.
Publicado 2020

Inability to sustain intraphagolysosomal killing of Staphylococcus aureus predisposes to bacterial persistence in macrophages

por Jubrail, Jamil, Morris, Paul, Bewley, Martin A., Stoneham, Simon, Johnston, Simon A., Foster, Simon J., Peden, Andrew A., Read, Robert C., Marriott, Helen M., Dockrell, David H.
Publicado 2015

Blood vessel occlusion by Cryptococcus neoformans is a mechanism for haemorrhagic dissemination of infection

por Gibson, Josie F., Bojarczuk, Aleksandra, Evans, Robert J., Kamuyango, Alfred Alinafe, Hotham, Richard, Lagendijk, Anne K., Hogan, Benjamin M., Ingham, Philip W., Renshaw, Stephen A., Johnston, Simon A.
Publicado 2022

Altered Macrophage Polarization Induces Experimental Pulmonary Hypertension and Is Observed in Patients With Pulmonary Arterial Hypertension

por Zawia, Amira, Arnold, Nadine D., West, Laura, Pickworth, Josephine A., Turton, Helena, Iremonger, James, Braithwaite, Adam T., Cañedo, Jaime, Johnston, Simon A., Thompson, A.A. Roger, Miller, Gaynor, Lawrie, Allan
Publicado 2020

Cryptococcus neoformans Intracellular Proliferation and Capsule Size Determines Early Macrophage Control of Infection

por Bojarczuk, Aleksandra, Miller, Katie A., Hotham, Richard, Lewis, Amy, Ogryzko, Nikolay V., Kamuyango, Alfred A., Frost, Helen, Gibson, Rory H., Stillman, Eleanor, May, Robin C., Renshaw, Stephen A., Johnston, Simon A.
Publicado 2016

Tribbles 3 deficiency promotes atherosclerotic fibrous cap thickening and macrophage-mediated extracellular matrix remodelling

por Martinez-Campesino, Laura, Kocsy, Klaudia, Cañedo, Jaime, Johnston, Jessica M., Moss, Charlotte E., Johnston, Simon A., Hamby, Stephen, Goodall, Alison H., Redgrave, Jessica, Francis, Sheila E., Kiss-Toth, Endre, Wilson, Heather L.
Publicado 2022

Vomocytosis of live pathogens from macrophages is regulated by the atypical MAP kinase ERK5

por Gilbert, Andrew S., Seoane, Paula I., Sephton-Clark, Poppy, Bojarczuk, Aleksandra, Hotham, Richard, Giurisato, Emanuele, Sarhan, Adil R., Hillen, Amy, Velde, Greetje Vande, Gray, Nathanael S., Alessi, Dario R., Cunningham, Debbie L., Tournier, Cathy, Johnston, Simon A., May, Robin C.
Publicado 2017