Histone deacetylase inhibitors: potential targets responsible for their anti-cancer effect

por Dickinson, Michael, Johnstone, Ricky W., Prince, H. Miles
Publicado 2010

The anticancer effects of HDAC inhibitors require the immune system

por West, Alison C, Smyth, Mark J, Johnstone, Ricky W
Publicado 2014

The combination of histone deacetylase inhibitors with immune-stimulating antibodies has potent anti-cancer effects

por West, Alison C., Christiansen, Ailsa J., Smyth, Mark J., Johnstone, Ricky W.
Publicado 2012

Genome-wide functional genomic and transcriptomic analyses for genes regulating sensitivity to vorinostat

por Falkenberg, Katrina J, Gould, Cathryn M, Johnstone, Ricky W, Simpson, Kaylene J
Publicado 2014

Enhancing the antitumor effects of radiotherapy with combinations of immunostimulatory antibodies

por Verbrugge, Inge, Galli, Mara, Smyth, Mark J., Johnstone, Ricky W., Haynes, Nicole M.
Publicado 2012

Overview of Histone Deacetylase Inhibitors in Haematological Malignancies

por Bishton, Mark J., Johnstone, Ricky W., Dickinson, Michael, Harrison, Simon, Prince, H. Miles
Publicado 2010

Down-regulation of a pro-apoptotic pathway regulated by PCAF/ADA3 in early stage gastric cancer

por Brasacchio, Daniella, Busuttil, Rita A., Noori, Tahereh, Johnstone, Ricky W., Boussioutas, Alex, Trapani, Joseph A.
Publicado 2018

Whole genome CRISPR screening identifies TOP2B as a potential target for IMiD sensitization in multiple myeloma

por Costacurta, Matteo, Vervoort, Stephin J, Hogg, Simon J, Martin, Benjamin P, Johnstone, Ricky W, Shortt, Jake
Publicado 2020

Combining the differentiating effect of panobinostat with the apoptotic effect of arsenic trioxide leads to significant survival benefit in a model of t(8;21) acute myeloid leukemi...

por Salmon, Jessica M, Bots, Michael, Vidacs, Eva, Stanley, Kym L, Atadja, Peter, Zuber, Johannes, Johnstone, Ricky W
Publicado 2015

Correction to: Combining the differentiating effect of panobinostat with the apoptotic effect of arsenic trioxide leads to significant survival benefit in a model of t(8;21) acute...

por Salmon, Jessica M., Bots, Michael, Vidacs, Eva, Stanley, Kym L., Atadja, Peter, Zuber, Johannes, Johnstone, Ricky W.
Publicado 2020

Socrates: identification of genomic rearrangements in tumour genomes by re-aligning soft clipped reads

por Schröder, Jan, Hsu, Arthur, Boyle, Samantha E., Macintyre, Geoff, Cmero, Marek, Tothill, Richard W., Johnstone, Ricky W., Shackleton, Mark, Papenfuss, Anthony T.
Publicado 2014

Initiation of Apoptosis by Granzyme B Requires Direct Cleavage of Bid, but Not Direct Granzyme B–Mediated Caspase Activation

por Sutton, Vivien R., Davis, Joanne E., Cancilla, Michael, Johnstone, Ricky W., Ruefli, Astrid A., Sedelies, Karin, Browne, Kylie A., Trapani, Joseph A.
Publicado 2000

Stepwise progression of β-selection during T cell development involves histone deacetylation

por Chann, Anchi S, Charnley, Mirren, Newton, Lucas M, Newbold, Andrea, Wiede, Florian, Tiganis, Tony, Humbert, Patrick O, Johnstone, Ricky W, Russell, Sarah M
Publicado 2022

A role for multiple chimeric antigen receptor-expressing leukocytes in antigen-specific responses to cancer

por Yong, Carmen S.M., John, Liza B., Devaud, Christel, Prince, Miles H., Johnstone, Ricky W., Trapani, Joseph A., Darcy, Phillip K., Kershaw, Michael H.
Publicado 2016

JAK2 is dispensable for maintenance of JAK2 mutant B-cell acute lymphoblastic leukemias

por Kim, Sang-Kyu, Knight, Deborah A., Jones, Lisa R., Vervoort, Stephin, Ng, Ashley P., Seymour, John F., Bradner, James E., Waibel, Michaela, Kats, Lev, Johnstone, Ricky W.
Publicado 2018

Imprinted CDKN1C Is a Tumor Suppressor in Rhabdoid Tumor and Activated by Restoration of SMARCB1 and Histone Deacetylase Inhibitors

por Algar, Elizabeth M., Muscat, Andrea, Dagar, Vinod, Rickert, Christian, Chow, C. W., Biegel, Jaclyn A., Ekert, Paul G., Saffery, Richard, Craig, Jeff, Johnstone, Ricky W., Ashley, David M.
Publicado 2009

Lethal Giant Larvae 1 Tumour Suppressor Activity Is Not Conserved in Models of Mammalian T and B Cell Leukaemia

por Hawkins, Edwin D., Oliaro, Jane, Ramsbottom, Kelly M., Ting, Stephen B., Sacirbegovic, Faruk, Harvey, Michael, Kinwell, Tanja, Ghysdael, Jacques, Johnstone, Ricky W., Humbert, Patrick O., Russell, Sarah M.
Publicado 2014

Bcor loss perturbs myeloid differentiation and promotes leukaemogenesis

por Kelly, Madison J., So, Joan, Rogers, Amy J., Gregory, Gareth, Li, Jason, Zethoven, Magnus, Gearhart, Micah D., Bardwell, Vivian J., Johnstone, Ricky W., Vervoort, Stephin J., Kats, Lev M.
Publicado 2019

Functional Crosstalk between Type I and II Interferon through the Regulated Expression of STAT1

por Gough, Daniel J., Messina, Nicole L., Hii, Linda, Gould, Jodee A., Sabapathy, Kanaga, Robertson, Ashley P. S., Trapani, Joseph A., Levy, David E., Hertzog, Paul J., Clarke, Christopher J. P., Johnstone, Ricky W.
Publicado 2010

Distinct modulation of IFNγ-induced transcription by BET bromodomain and catalytic P300/CBP inhibition in breast cancer

por Hogg, Simon J., Motorna, Olga, Kearney, Conor J., Derrick, Emily B., House, Imran G., Todorovski, Izabela, Kelly, Madison J., Zethoven, Magnus, Bromberg, Kenneth D., Lai, Albert, Beavis, Paul A., Shortt, Jake, Johnstone, Ricky W., Vervoort, Stephin J.
Publicado 2022