The generation of HepG2 transmitochondrial cybrids to reveal the role of mitochondrial genotype in idiosyncratic drug-induced liver injury

por Ball, Amy Louise, Jolly, Carol E, Lennon, Mark G, Lyon, Jonathan J, Alfirevic, Ana, Chadwick, Amy E
Publicado 2023

The utility of a differentiated preclinical liver model, HepaRG cells, in investigating delayed toxicity via inhibition of mitochondrial-replication induced by fialuridine

por Jolly, Carol E., Douglas, Oisin, Kamalian, Laleh, Jenkins, Rosalind E., Beckett, Alison J., Penman, Sophie L., Williams, Dominic P., Monshouwer, Mario, Simic, Damir, Snoeys, Jan, Park, B. Kevin, Chadwick, Amy E.
Publicado 2020