M(1)-selective muscarinic allosteric modulation enhances cognitive flexibility and effective salience in nonhuman primates

por Hassani, Seyed A., Neumann, Adam, Russell, Jason, Jones, Carrie K., Womelsdorf, Thilo
Publicado 2023

Partial mGlu(5) Negative Allosteric Modulator M-5MPEP Demonstrates Antidepressant-Like Effects on Sleep Without Affecting Cognition or Quantitative EEG

por Holter, Kimberly M., Lekander, Alex D., LaValley, Christina M., Bedingham, Elizabeth G., Pierce, Bethany E., Sands, L. Paul, Lindsley, Craig W., Jones, Carrie K., Gould, Robert W.
Publicado 2021

Muscarinic M(5) receptors modulate ethanol seeking in rats

por Berizzi, Alice E., Perry, Christina J., Shackleford, David M., Lindsley, Craig W., Jones, Carrie K., Chen, Nicola A., Sexton, Patrick M., Christopoulos, Arthur, Langmead, Christopher J., Lawrence, Andrew J.
Publicado 2018

Chemical Modulation of Mutant mGlu(1) Receptors Derived from Deleterious GRM1 Mutations Found in Schizophrenics

por Cho, Hyekyung P., Garcia-Barrantes, Pedro M., Brogan, John T., Hopkins, Corey R., Niswender, Colleen M., Rodriguez, Alice L., Venable, Daryl F., Morrison, Ryan D., Bubser, Michael, Daniels, J. Scott, Jones, Carrie K., Conn, P. Jeffrey, Lindsley, Craig W.
Publicado 2014

Discovery of (S)-2-Cyclopentyl-N-((1-isopropylpyrrolidin2-yl)-9-methyl-1-oxo-2,9-dihydro-1H-pyrrido[3,4-b]indole-4-carboxamide (VU0453379): A Novel, CNS Penetrant Glucagon-Like Pep...

por Morris, Lindsey C., Nance, Kellie D., Gentry, Patrick R., Days, Emily L., Weaver, C. David, Niswender, Colleen M., Thompson, Analisa D., Jones, Carrie K., Locuson, Chuck W., Morrison, Ryan D., Daniels, J. Scott, Niswender, Kevin D., Lindsley, Craig W.
Publicado 2014

Discovery of N-(5-Fluoropyridin-2-yl)-6-methyl-4-(pyrimidin-5-yloxy)picolinamide (VU0424238): A Novel Negative Allosteric Modulator of Metabotropic Glutamate Receptor Subtype 5 Sel...

por Felts, Andrew S., Rodriguez, Alice L., Blobaum, Anna L., Morrison, Ryan D., Bates, Brittney S., Thompson Gray, Analisa, Rook, Jerri M., Tantawy, Mohammed N., Byers, Frank W., Chang, Sichen, Venable, Daryl F., Luscombe, Vincent B., Tamagnan, Gilles D., Niswender, Colleen M., Daniels, J. Scott, Jones, Carrie K., Conn, P. Jeffrey, Lindsley, Craig W., Emmitte, Kyle A.
Publicado 2017

Selective Activation of M(4) Muscarinic Acetylcholine Receptors Reverses MK-801-Induced Behavioral Impairments and Enhances Associative Learning in Rodents

por Bubser, Michael, Bridges, Thomas M., Dencker, Ditte, Gould, Robert W., Grannan, Michael, Noetzel, Meredith J., Lamsal, Atin, Niswender, Colleen M., Daniels, J. Scott, Poslusney, Michael S., Melancon, Bruce J., Tarr, James C., Byers, Frank W., Wess, Jürgen, Duggan, Mark E., Dunlop, John, Wood, Michael W., Brandon, Nicholas J., Wood, Michael R., Lindsley, Craig W., Conn, P. Jeffrey, Jones, Carrie K.
Publicado 2014

Tetrahydronaphthyridine and Dihydronaphthyridinone Ethers As Positive Allosteric Modulators of the Metabotropic Glutamate Receptor 5 (mGlu(5))

por Turlington, Mark, Malosh, Chrysa, Jacobs, Jon, Manka, Jason T., Noetzel, Meredith J., Vinson, Paige N., Jadhav, Satyawan, Herman, Elizabeth J., Lavreysen, Hilde, Mackie, Claire, Bartolomé-Nebreda, José M., Conde-Ceide, Susana, Martín-Martín, M. Luz, Tong, Han Min, López, Silvia, MacDonald, Gregor J., Steckler, Thomas, Daniels, J. Scott, Weaver, C. David, Niswender, Colleen M., Jones, Carrie K., Conn, P. Jeffrey, Lindsley, Craig W., Stauffer, Shaun R.
Publicado 2014