ABPP-HT - High-Throughput Activity-Based Profiling of Deubiquitylating Enzyme Inhibitors in a Cellular Context

por Jones, Hannah B. L., Heilig, Raphael, Fischer, Roman, Kessler, Benedikt M., Pinto-Fernández, Adán
Publicado 2021

ABPP-HT*—Deep Meets Fast for Activity-Based Profiling of Deubiquitylating Enzymes Using Advanced DIA Mass Spectrometry Methods

por Jones, Hannah B. L., Heilig, Raphael, Davis, Simon, Fischer, Roman, Kessler, Benedikt M., Pinto-Fernández, Adán
Publicado 2022

Sensing Enzyme Activation Heat Capacity at the Single-Molecule Level Using Gold-Nanorod-Based Optical Whispering Gallery Modes

por Subramanian, Sivaraman, Jones, Hannah B.L., Frustaci, Simona, Winter, Samuel, van der Kamp, Marc W., Arcus, Vickery L., Pudney, Christopher R., Vollmer, Frank
Publicado 2021

Structural Premise of Selective Deubiquitinase USP30 Inhibition by Small-Molecule Benzosulfonamides

por O'Brien, Darragh P., Jones, Hannah B.L., Guenther, Franziska, Murphy, Emma J., England, Katherine S., Vendrell, Iolanda, Anderson, Malcolm, Brennan, Paul E., Davis, John B., Pinto-Fernández, Adán, Turnbull, Andrew P., Kessler, Benedikt M.
Publicado 2023

Chemical Mapping Exposes the Importance of Active Site Interactions in Governing the Temperature Dependence of Enzyme Turnover

por Winter, Samuel D., Jones, Hannah B. L., Răsădean, Dora M., Crean, Rory M., Danson, Michael J., Pantoş, G. Dan, Katona, Gergely, Prentice, Erica, Arcus, Vickery L., van der Kamp, Marc W., Pudney, Christopher R.
Publicado 2021

Monoclonal antibody stability can be usefully monitored using the excitation-energy-dependent fluorescence edge-shift

por Knight, Michael J., Woolley, Rachel E., Kwok, Anthony, Parsons, Stuart, Jones, Hannah B. L., Gulácsy, Christina E., Phaal, Polly, Kassaar, Omar, Dawkins, Kieran, Rodriguez, Elizabeth, Marques, Andreia, Bowsher, Leo, Wells, Stephen A., Watts, Andrew, vandenElsen, Jean M. H., Turner, Alison, O'Hara, John, Pudney, Christopher R.
Publicado 2020